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[evaluation of the indirect immunofluorescence test for the diagnosis of bancroftian filariasis using microfilariae w. bancrofti as the antigen, in recife-pe, brazil].the authors analysed the indirect immunofluorescence assay, for the diagnosis of bancroftian filariasis using papain treated w. bancrofti microfilariae as antigen, widely used in recife-brazil. sera from 50 patients with several clinical forms of the disease including asymptomatic carriers, tropical pulmonary eosinophilia, elephantiasis, filarial fever and chyluria were analysed. for the control group, 50 individuals were selected, living at least 5 years in endemic area, with neither previous d ...19911844968
filariasis programme--recife--brazil. 19872908187
comparative efficacy of three different diethylcarbamazine regimens in lymphatic filariasis.to assess the efficacy of diethylcarbamazine (dec) in clearing wuchereria bancrofti microfilariae (mf) from the circulation, we conducted a single blind hospital-based therapeutic trial of 3 dec regimens. all patients were assessed by filtration of 1 ml of venous blood taken before and 1, 3, 6 and 12 months after dec administration. the efficacy of a 12 d course of 6 mg/kg dec once daily was identical to that of a similar course with 2 mg/kg given 3 times daily, indicating that split-dose treatm ...19957660449
amicrofilaraemic carriers of adult wuchereria bancrofti.to determine the extent to which wuchereria bancrofti infections can be detected in asymptomatic amicrofilaraemic men in greater recife, brazil, we studied 100 asymptomatic men who were long-term residents (> or = 15 years) of this filariasis-endemic area and who were amicrofilaraemic in 60 microl of capillary blood collected at night. increasing amounts (1, 5, and 10 ml) of venous blood were collected in consecutive weeks, filtered, and examined for microfilariae; 27 men were eventually found t ...19968758079
[history of lymphatic filariasis in pernambuco. i. epidemiologic and control aspects].this paper is a review of lymphatic bancroftian filariasis in the state of pernambuco. brazil. it shows that reports have existed since the 1st decade of the century. knowledge of the disease in several areas during different periods makes a retrospective analyses very interesting, particularly in great recife. it is in the city that the epidemiological and control aspects of the diseases are examinations in details.19969011889
epidemiological study of bancroftian filariasis in recife, northeastern brazil.wuchereria bancrofti in pernambuco was first documented in 1952 (azevedo & dobbin 1952), and since then it has been reported in surveys carried out in selected areas of recife. several surveys were carried out from 1981 to 1991 by sucam. in the 1985 sucam's report the disease is considered under control. the cpqam filariasis research program was established in 1985 and a filarial survey was carried out in the town of olinda, greater recife. in order to verify the real epidemiological situation, ...19969070407
[tropical filarial pulmonary eosinophilia and its differential diagnosis].the authors present a comprehensive review of tropical pulmonary eosinophilia (tpe) of filarial etiology and describe its differential diagnosis with similar syndromes. epidemiological, clinical, diagnostic, therapeutic and phisiopathological aspects are considered, with an emphasis on new advances in our knowledge of lymphatic filariasis and their implication for improved understanding of tpe and similar syndromes. a tpe-like syndrome, which is caused by intestinal helminth infections, occurs i ...19989659744
[bancroftian filariasis in brazil].the past and present distribution of bancroftian filariasis in brazil is reviewed. parasitological and entomological surveys were conducted between 1951 and 1958, the autochthonous transmission of wuchereria bancrofti having been found only in 11 places in the country as follows, with the corresponding prevalences; ponta grossa (sc), 14.5% belém (pa), 9.8%; barra de laguna (sc), 9.4%; recife (pe), 6.9%; castro alves (ba), 5.9%; florianópolis (sc), 1.4%; são luis (ma), 0.6%; salvador (ba), 0.4%; ...19989699353
[views on the municipalization of lymphatic filariasis control in greater metropolitan recife].lymphatic filariasis is caused by the nematodes brugia malayi, brugia timori, and wuchereria bancrofti. the disease occurs in developing countries and is more frequent in urban areas. an estimated 4 billion people live in at-risk areas. in brazil the endemic is caused by w. bancrofti and was first documented in 1878. it was first detected in recife in 1952. currently, recife and belém are the only cities in brazil where the endemic is considered a public health problem. the objectives of this st ...199910203460
screening of army soldiers for wuchereria bancrofti infection in the metropolitan recife region, brazil: implications for epidemiological surveillance.between 1989 and 1995, blood surveys were performed for wuchereria bancrofti infection in several barracks of the brazilian army in the metropolitan recife region. for initial screening, 60 microliters of capillary blood were examined for microfilaria. all men who tested positive had microfilaria quantified by filtration of venous blood through a polycarbonate membrane. of 23,773 men screened, 585 (2.5%) had microfilaria (mf). microfilarial density ranged from < 1-8706 mf/ml of blood. thirteen i ...199910470342
children and adolescents infected with wuchereria bancrofti in greater recife, brazil: a randomized, year-long clinical trial of single treatments with diethylcarbamazine or diethylcarbamazine-albendazole.in filariasis-endemic areas beyond sub-saharan africa, the world health organization's recommended strategy for interrupting transmission of the causative parasites is annual, single-dose, mass treatment with a combination of diethylcarbamazine (dec; given at 6 mg/kg) and albendazole (alb; given at 400 mg) for 4-6 years (the minimum estimated life-span of the adult parasites). in an open, hospital-based, randomized and controlled trial, with a blinded evaluation of outcome, 82 children and adole ...200717550648
diagnosis of wuchereria bancrofti infection by the polymerase chain reaction using urine and day blood samples from amicrofilaraemic patients.a sensitive and specific polymerase chain reaction (pcr) based on a highly repeated deoxyribonucleic acid (dna) sequence (188 bp; sspi repeat) was tested for the detection of wuchereria bancrofti dna in blood and urine samples collected during the day from individuals in coque, recife, brazil, an endemic area for w. bancrofti. all microfilaraemic individuals were also positive by pcr, irrespective of the samples used. the pcr system was capable of detecting w. bancrofti dna in amicrofilaraemic i ...19989861400
ultrasonographic detection of living adult wuchereria bancrofti using a 3.5-mhz transducer.adult wuchereria bancrofti can be readily detected by ultrasound in the lymphatic vessels of the spermatic cord with a 7.5-mhz transducer, but most ultrasound machines in developing countries are equipped with 3.5-mhz transducers. to assess the potential for ultrasound as a tool for diagnosis and epidemiologic assessment in lymphatic filariasis, we compared the performance of 3.5-mhz and 7.5-mhz transducers in 61 men in recife, brazil. all men had three ultrasound examinations using a 3.5 mhz tr ...19989749633
risk factors for the occurrence of bancroftian filariasis infection in children living in endemic areas of northeast of brazil.the objective of this study was to identify biological and social risk factors for the occurrence of microfilaraemia in a population of 1464 children of both sexes aged 5-14 years, living in two highly endemic areas of recife a city in the northeast of brazil. a survey was performed from december 1990 to july 1991 and the microfilaraemia was examined by the thick-drop technique using 45 microliters of peripheral blood. information was obtained about use of bednet, length of time living in area a ...19989604596
detection of living adult wuchereria bancrofti in a patient with tropical pulmonary eosinophilia.tropical pulmonary eosinophilia (tpe) is a relatively unusual and diagnostically challenging manifestation of infection with wuchereria bancrofti. the pathogenesis of tpe remains unclear, although immune hyperresponsiveness to the microfilarial stage of the parasite is thought to play an essential role. microfilariae are almost never detected in the peripheral blood of persons with tpe and living adult worms have not been reported. thus, no parasitologic marker has existed with which to assess t ...19969181082
occurrence of living adult wuchereria bancrofti in the scrotal area of men with microfilaraemia.to determine the frequency with which living adult wuchereria bancrofti can be detected by ultrasound in the scrotal area of men with filarial infection, we used a 7.5 mhz transducer to perform weekly ultrasound examinations on 100 microfilaraemic men (18-34 years old) from greater recife, brazil. the peculiar pattern of movement that characterizes the adult worm image on ultrasound (the filaria dance sign) was detected in the lymphatic vessels of the spermatic cord in 80 men (bilaterally in 29 ...19968730313
ultrasonographic evidence of abnormal lymphatic vessels in young men with adult wuchereria bancrofti infection in the scrotal area.we determined the prevalence and magnitude of dilatation of the lymphatic vessels of the spermatic cord in men infected with wuchereria bancrofti, which is known major cause of hydrocele in the tropics.19968683691
studies on the periodicity and intravascular distribution of wuchereria bancrofti microfilariae in paired samples of capillary and venous blood from recife, brazil.we examined the periodicity and intravascular distribution of wuchereria bancrofti microfilariae (mf) and determined the effect of these parasite properties on the accuracy of blood filming and filtration methods for diagnosis of bancroftian filariasis in the endemic area of recife, brazil. microfilariae in both venous and capillary blood exhibited a nocturnal periodicity pattern with a relatively high amplitude. overall, capillary blood contained approximately 1.25 times the number of mf presen ...19968665395
ivermectin treatment of bancroftian filariasis in recife, brazil.to determine the effectiveness of single oral dosages of ivermectin ranging between 20 and 200 micrograms/kg and to make detailed observations of both the kinetics of parasite killing and the adverse reactions induced by treatment, the present double-blind study on ivermectin treatment of lymphatic filariasis caused by wuchereria bancrofti was undertaken with 43 microfilaremic patients in recife, brazil. follow-up at one year indicated equivalent efficacy for the 20-, 100-, and 200-micrograms/kg ...19948147492
bancroftian filariasis in two urban areas of recife, brazil: pre-control observations on infection and disease.bancroftian filariasis is a major public health problem in the city of recife in north-eastern brazil. in some of its urban areas microfilaraemia prevalence reaches 14%. this study describes epidemiological characteristics, infection and disease, in 2 urban areas, coque and mustardinha, before control measures were applied. the parasitological survey was performed by a 'door-to-door' census covering 5563 subjects, aged between 5 and 65 years. microfilaraemia was detected by the thick drop techni ...19957570866
wuchereria bancrofti microfilarial density of autochthonous cases and natural culex infectivity rates in northeast brazil.autochthonous wuchereria bancrofti microfilaraemic cases from three neighbouring cities of northeast brazil (recife, jaboatao and olinda) were selected from thick smear or filtration positive individuals and classified by their microfilarial (mf) densities through polycarbonate membrane blood filtration. individuals were subdivided into two groups: autochthonous cases without any previous specific drug administrations (group a) and those with one or more previous dec treatments (group b). in rec ...19921597880
susceptibility status of culex quinquefasciatus (diptera: culicidae) populations to the chemical insecticide temephos in pernambuco, brazil.culex quinquefasciatus is the vector of many agents of human diseases, including wuchereria bancrofti, the parasite that causes bancroftian filariasis, an endemic disease in pernambuco state, brazil. although temephos is not currently used to control c. quinquefasciatus, the species might be under a selection process from incidental exposure to this compound. this study aimed to evaluate the susceptibility status of c. quinquefasciatus to temephos, using bioassays, and to investigate its putativ ...201323576326
occurrence of immature forms of culicids (insecta: diptera) in the northeastern region of brazil.the culicidae family is represented by approximately 3,610 species, among which many are involved in transmission of pathogens and parasites, thus presenting great medical-veterinary importance. in brazil, the state of pernambuco is considered an endemic area for many diseases vectored by mosquitoes, such as human and canine filariasis, caused by wuchereria bancrofti and dirofilaria immitis, respectively. the aim of this study was to evaluate the occurrence of immature forms of culicids, over an ...201425054499
intrascrotal nodules in adult men as a marker for filarial granuloma in a bancroftian filariasis-endemic area.a retrospective study was undertaken in recife, brazil to evaluate the specificity of intrascrotal nodules detected by physical examination as a marker of dead or degenerating adult wuchereria bancrofti worms (filarial granuloma). a total of 372 nodules from 340 adult male patients (mean age 23.1 years) were studied. of those, 253 (68%) nodules were from 226 patients treated with antifilarial drugs (group 1) and 119 (32%) nodules were considered non-drug related and were obtained from 114 patien ...200919635891
sex ratio of wuchereria bancrofti in surgical specimens from an endemic area of brazil.the sex ratio of adult wuchereria bancrofti from 172 histologically diagnosed cases of lymphatic filariasis, all from an endemic area of recife, in north-eastern brazil, was investigated. of 172 tissue specimens examined, 74 (43%) were lymph nodes and 98 (57%) lymphatic-vessel segments. the morphology of the worms was generally disrupted, in some cases to the point where the worms were almost completely absorbed by the granulomatous inflammatory response. parasite gender was clearly determined i ...200818348777
sensitivity of the immunochromatographic card test relative to detection of adult wuchereria bancrofti worms by ultrasound.the diagnosis of active infection in bancroftian filariasis continues to pose an important and continuously evolving challenge to filariasis-endemic countries and to health personnel. sensitivity of the immunochromatographic card test (ict) relative to detection of adult wuchereria bancrofti worms by ultrasound was evaluated in a retrospective study conducted in the center for teaching, research and tertiary referral hospital for bancroftian filariasis (federal university of pernambuco) in recif ...200818187781
does longevity of adult wuchereria bancrofti increase with decreasing intensity of parasite transmission? insights from clinical observations.to interrupt transmission of wuchereria bancrofti, a parasite that causes lymphatic filariasis, mass treatment of at-risk populations with antifilarial drugs is recommended for 4-6 years, the minimum estimated adult worm lifespan. factors associated with adult worm longevity are unknown. in recife, brazil, we conducted a retrospective cohort study of 57 men whose adult w. bancrofti were not sensitive to diethylcarbamazine and who were followed with semi-annual physical examinations (to detect in ...200516165175
human toxocariasis: frequency of anti-toxocara antibodies in children and adolescents from an outpatient clinic for lymphatic filariasis in recife, northeast brazil.in a transversal study on a sample of 386 children and adolescents from an outpatient clinic for filariasis in recife, northeast brazil, the frequency of anti-toxocara antibodies and its relation to age, gender, number of peripheral eosinophils, wuchereria bancrofti microfilariae and intestinal helminths was determined. the total anti-toxocara igg antibody frequency was 39.4%, by elisa technique. the difference in frequency between males (40.1%) and females (37.6%) was not statistically signific ...200415141276
[the occurrence and distribution of lymphatic filariasis in greater metropolitan recife: the case of an endemic area in jaboatão dos guararapes, pernambuco, brazil].this article analyzes the results of an epidemiological survey on the occurrence and distribution of lymphatic filariasis in cavaleiro, a district in the city of jaboatão dos guararapes in greater metropolitan recife, pernambuco state, brazil. the district was divided into 12 areas, and a cross-sectional technique was used to examine 9,520 individuals, of whom 2.2% were found to be infected. there were positive cases in 11 of the areas. the prevalence rate ranged from 0% to 5.15%. the majority ( ...200314666231
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