| towards eliminating lymphatic filariasis in papua new guinea: impact of annual single-dose mass treatment on transmission of wuchereria bancrofti in east sepik province. | the impact of annual single-dose community-wide treatment on the transmission of wuchereria bancrofti was investigated in 5 villages in the east sepik province where pretreatment prevalence of microfilaraemia ranged from 34% to 73%. anopheles punctulatus and an. koliensis were the only carriers of the parasite. 3 villages received diethylcarbamazine citrate (dec) in combination with ivermectin (ivr) and 2 received dec alone. the rate and intensity of microfilaraemia were both reduced in all 5 vi ... | 2000 | 11939298 |
| the effect of pregnancy on wuchereria bancrofti microfilarial load in humans. | as part of a drug trial against bancroftian filariasis in the east sepik province of papua new guinea we measured the pre-treatment microfilarial densities of 2219 individuals. mean levels generally increased with age in both sexes, with a tendency to plateau at the highest ages. however, there was a reduction among women of approximately reproductive age. allowing for the tendency for aggregation to decrease with age, this reduction was statistically significant. however, a comparison of pregna ... | 1999 | 10466122 |
| transmission dynamics of wuchereria bancrofti in east sepik province, papua new guinea. | bancroftian filariasis is endemic in many areas of papua new guinea. this study describes the entomologic indices of transmission near dreikikir in east sepik province, papua new guinea. a total of 1,735 culicine mosquitoes, including culex and mansonia species, were dissected, but none were infected with filarial larvae. in contrast, anopheles punctulatus and an. koliensis were found to be potential vectors: 7.3% of anopheles were infected and the mean number of first- to third-stage larvae per ... | 1996 | 8686774 |
| filarial vector studies in a diethylcarbamazine-treated and in untreated villages in papua new guinea. | entomological studies were undertaken in three villages in the east sepik province of papua new guinea. the inhabitants of one village, nanaha, had been treated with diethylcarbamazine (dec) to reduce the prevalence and density of microfilaraemia of wuchereria bancrofti. no intervention was undertaken in the other two villages, yauatong and musenau, in which bancroftian filariasis was present but with markedly different human prevalence rates and mean parasite densities. in yauatong, infection r ... | 1995 | 8544229 |
| parasitologic and clinical features of bancroftian filariasis in a community in east sepik province, papua new guinea. | bancroftian filariasis has been reported in several areas of papua new guinea. the epidemiologic features and natural history of wuchereria bancrofti infection in this geographic region, however, have not been well-defined. the objective of this study was to assess the parasitological and clinical features of bancroftian filariasis in a community in east sepik province, papua new guinea. in a village of 99 individuals, the overall prevalence of microfilaremia was 68%. the microfilarial carrier r ... | 1984 | 6391222 |
| age specific patterns of change in the dynamics of wuchereria bancrofti infection in papua new guinea. | results of a longitudinal study of the age-specific dynamics of wuchereria bancrofti infection in a community of east sepik province, papua new guinea (png) are described. microfilarial (mf) density and serum levels of w. bancrofti phosphorylcholine-containing antigen (pc-ag) in individuals were used as indirect measures of adult worm burden. these parasitological data were collected from 126 subjects greater than 4 years of age at two time points, 12 months apart, prior to the administration of ... | 1991 | 2063955 |