Publications

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altitude and the risk of bites from mosquitoes infected with malaria and filariasis among the mianmin people of papua new guinea.the mianmin are a mobile population occupying a remote lower montane area at 100-1200 m altitude in the north-western interior of papua new guinea (png). major medical problems include malaria and bancroftian filariasis. an entomological survey conducted along an altitudinal transect from 170 to 1000m identified anopheles koliensis as the predominant malaria vector below 650 m, with a. punctulatus dominating at the higher elevations. proportions of mosquitoes with malaria circumsporozoite antige ...19979093615
a study of the cd4: cd8 ratio in peripheral t lymphocytes of rural papua new guineans: a reduced ratio assessed with regard to infectious agents.the cd4:cd8 ratio in peripheral t lymphocytes was determined in 123 papua new guineans aged over 5 years from rumginae, a rural area of the western province. 18 people had a ratio less than 1.0. no antibody response to human immunodeficiency virus 1 (hiv 1) was found within the group. hepatitis b surface antigen was more commonly associated with a cd4:cd8 ratio less than 1.0 than were microfilaraemia or a positive mantoux test. hepatitis b infection may be one of the causes of the cd4:cd8 ratio ...19938059546
diethylcarbamazine in the control of bancroftian filariasis in the ok tedi area of papua new guinea: phase 2--annual single-dose treatment.the phase 1 semiannual single-dose 6 mg/kg diethylcarbamazine (dec) treatment program demonstrated a significant reduction for wuchereria bancrofti in the ok tedi area of western province, papua new guinea. the rate of detectable microfilaraemia was effectively reduced from 39% to 11% and mean microfilarial (mf) densities from 79mf/20 microliters to 19mf/20 microliters. the phase 2 annual single-dose treatment of 6mg/kg dec not only maintained the gains made during phase 1 but reduced the microf ...19947771117
malaria and filariasis in the ok tedi region of the star mountains, papua new guinea.malaria and filariasis surveys were carried out as part of a broader general health survey between december, 1982 and may, 1983 in the ok tedi region of the star mountains, western province. malaria, tropical splenomegaly syndrome (tss) and anaemia were identified as significant health problems. malaria slide positivity rates of 64.9% in children 2 to 9 years of age and 19.5% in adults 15 years and older indicate high levels of stable malaria transmission. infections with plasmodium falciparum w ...19836593955
serological evaluation of the macrofilaricidal effects of diethylcarbamazine treatment in bancroftian filariasis.an mr 200,000 phosphorylcholine-containing antigen (pc-ag) of predominantly adult worm origin was found in the sera of humans infected with wuchereria bancrofti. this paper describes results of a longitudinal study of changes in levels of pc-ag in response to diethylcarbamazine (dec) therapy as measured by two-site immunoradiometric assay (irma) and western blotting. one hundred thirty-two residents of a bancroftian filariasis-endemic area of papua new guinea (png) were treated with a 72 mg/kg d ...19912063956
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