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a clinico-epidemiological perspective of lymphatic filariasis in satyabadi block of puri district, orissa.lymphatic filariasis is a major public health problem in the coastal district of orissa. however, no systematic studies have been done to document the prevalence of microfilaraemia/disease in different regions of the state. therefore, the present cross sectional study was undertaken during 1996-97 to obtain information on the clinical and epidemiological status of the disease in satyabadi block area of puri district, known to be endemic for filariasis.200111785453
a long-term follow-up of asymptomatic amicrofilaraemic individuals living in a filaria-endemic region of orissa, india: infection and disease status.a group of asymptomatic amicrofilaraemic individuals (endemic normals) aged > 12 years was identified in 2 filaria-endemic villages of orissa, india in 1990 (bajapur village, n = 40) and in 1994 (olosingh village, n = 47). they were re-examined for microfilaraemia and disease status in the year 2000 after a 10-year and a 6-year period. studies conducted at both villages yielded a similar pattern in the development of disease. above 85% of the females remained normal, compared to 54% of males. re ...200111579885
occurrence of asymptomatic microscopic haematuria in a filarial endemic area of orissa, india.to determine the frequency of occurrence of asymptomatic microscopic haematuria in filarial endemic area of orissa, where the mf rate and disease rate were observed to be 14.8% and 37.2% respectively, clinical examination, night blood smear examination, morning midstream urine examination were conducted on 697 persons-randomly selected from all age groups in 8 villages of puri tehsil. out of them, 15.6% were found to have asymptomatic haematuria (grade i-14.7%, grade ii-0.6%, grade-iii 0.3%). th ...200011198403
bancroftian filariasis: prevalence of antigenaemia and endemic normals in orissa, india. 200011132379
transmission dynamics of filariasis in khurdha district of orissa, india.a three year longitudinal study was carried out to quantify the different parameters of filarial transmission in an endemic area of orissa state, india. parasitological surveys revealed mean microfilaria rate, microfilaria density and median microfilaria density (mfd-50) to be 9.41, 19.23 and 7.33, respectively. the per man hour density of the vector, culex quinquefasciatus varied from 24.2 to 66.0 with a peak in january. infection rate varied from 0.9 to 27.5%, while infectivity rate ranged bet ...19989740288
lymphatic filariasis and malaria: concomitant parasitism in orissa, india.concomitant parasitism with plasmodium spp. and wuchereria bancrofti was examined in orissa, india, to study the influence of one parasite infection on the other in human communities. a survey of 1815 nocturnal blood films in 11 villages indicated an overall prevalence of 9.6% for malaria and 8.5% for microfilaraemia. only 0.3% of the population harboured both parasites. analysis of the expected and observed distribution of cases of dual infection in each village did not indicate any significant ...19989692139
naturally acquired concomitant infections of bancroftian filariasis and human plasmodia in orissa.blood smears collected from fever cases for detection of malaria parasites during daytime showed concomitant infections of wuchereria bancrofti from 1989 to 1991 in bisra phc of district sundargarh, orissa. of the total 51,448 blood smears examined, 18,444 (35.84%) were positive for malaria parasites which comprised 3401 (18.44%) plasmodium vivax, 14,524 (78.75%) p. falciparum, 156 (0.84%) p. malariae and 363 (1.97%) mixed plasmodial infections. only 240 (0.46%) cases were positive for w. bancro ...19958549837
clinical filarial disease in two ethnic endemic communities of orissa, india.to evaluate the possible role of ethnicity in susceptibility to filarial infection, a comparative study of the prevalence of filarial infection was initiated in an endemic village inhabited by two ethnic populations of mainlanders and tribals. an age and sex matched sampled population of 591 mainlanders and 106 tribals was studied by detailed clinical and parasitological (60 mm3 blood) examinations. sera collected from both population groups (26 each) matched for clinical stage of infection were ...19938411307
ivermectin in the treatment of bancroftian filarial infection in orissa, india.ivermectin treatment was evaluated for its efficacy and side reactions in sixty patients of orissa with bancroftian filarial infection and microfilaremia. ivermectin was administered as a single oral dose at four dosage levels (20, 50, 100 and 200 micrograms/kg), and both microfilarial clearance and associated side reactions were monitored in a double blind fashion. blood microfilariae were cleared in all patients at all dosages within 1 to 14 days. in most patients microfilariae reappeared by t ...19938362313
prevalence of lymphatic nodule in a bancroftian endemic population.prevalence and clinical manifestation of lymphatic nodule in natural course of bancroftian filariasis was evaluated in a representative population of 2837 of a defined endemic community of orissa. detailed clinical and parasitological examination of study subjects revealed high disease (35.6%) and mf rate (15.8%) and mean microfilariae density (gm: 15.3 +/- 5.1 per 60 mm3 of blood) in the community. lymphatic filarial nodule was manifested in 216 (7.6%) subjects in different spectrum of filarial ...19937903138
disappearance of some brugia malayi foci from madhya pradesh, orissa and tamil nadu and co-existence of malayan and bancroftian filariasis in some pockets. 19807033355
bancroftian filariasis in two selected rural communities in puri district: orissa--a comparative study of filariometric data. 19846386963
epidemiological study on lymphatic filariasis in an endemic zone of orissa. 19863309037
detection of a new focus of brugia malayi infection in orissa.526 people were surveyed in a village called chudamani, in balasore district of orissa, for detection of asymptomatic microfilaria (mf) carriers. of these 36 (6.8 per cent) were cases found to harbour mf; 19 cases had brugia malayi, 4 wuchereria bancrofti and 5 cases had mixed infection. in 8 cases, species could not be ascertained. for the first time after 1955, a focus of b. malayi has been detected in orissa.19892681391
prevalence of wuchereria bancrofti infection in some coastal villages of ganjam, orissa.the endemicity of filariasis was assessed in 42 villages of coastal keluapalli phc in ganjam district of orissa. prevalence was found to vary greatly between extreme coastal and subcoastal villages. the infection was non existent in 12 coastal villages. age and sexwise distribution of filariasis cases have been analysed and presented.19901983014
high prevalence of wuchereria bancrofti infection as detected by immunochromatographic card testing in five districts of orissa, india, previously considered to be non-endemic.india accounts for over one-third of the world's burden of lymphatic filariasis (lf). although most coastal districts of orissa state (eastern india) are lf-endemic, the western districts of orissa are considered non-endemic. during a large-scale insecticide-treated bed net/microfinance trial, we tested one randomly selected adult (age 15-60 years) for lf from a random sample of microfinance-member households in five districts of western orissa, using immunochromatographic card testing (ict). ov ...201021122883
lymphatic filariasis in children: age dependent prevalence in an area of india endemic for wuchereria bancrofti infection.lymphatic filariasis has been considered as a disease of adults and most epidemiological surveys have excluded children. the prevalence of infection and clinical manifestations of the disease among children in the age group of 1-15 years was determined in a wuchereria bancrofti endemic area. the 1383 children from the rural villages of a coastal district (khurda), state of orissa, india, were studied. the finger prick blood (50ìl) samples were collected between 20:30 and 23:30 hours for parasito ...201020562812
molecular characterization of a truncated antigen (wb14) of sxp-1 of wuchereria bancrofti from four endemic regions in india.wb14 of wuchereria bancrofti, an orthologue of brugia malayi sxp-1 and w. bancrofti sxp-1, was amplified from genomic dna of w. bancrofti microfilaria collected from four distant geographical locations in india viz., vellore, bhubaneshwar, pondicherry and sevagram. the gene was sub-cloned in a prokaryotic vector prset and expressed in escherichia coli as a truncated protein (approximately 23kda). the nucleotide sequence of the gene is 98% similar to that of wbsxp-1 and is found to be intron-less ...201020138869
epidemiological, clinical and entomological observations on lymphatic filariasis in urban puri, orissa. 200819301704
antigenemia in young children living in wuchereria bancrofti-endemic areas of orissa, india.the prevalence of filarial antigenemia (an indicator of adult worm burden) among 610 children, aged 3-15 years, was determined in three endemic villages of khurda district, orissa, india, during 2005. prevalence of antigenemia, detected using og4c3 circulating filarial antigen elisa, was 32.6% compared with 10% microfilaraemia. although the prevalence of antigenemia increased marginally with increase in age, no significant difference was observed among the children of different age groups (28.3% ...200918809193
precontrol observations on lymphatic filariasis & geo-helminthiases in two coastal districts of rural orrisa.lymphatic filariasis (lf) is a major public health problem in india, accounting for 40 per cent of the global burden. the world health organization has launched a global programme to eliminate lf by 2020 and india is a signatory to it. orissa, an eastern indian state has long been known to be endemic for lf. prior to implementation of mass drug administration programme it is important to collect baseline data on filariasis and geo-helminthiases in the state. the present cross-sectional survey wa ...200516456251
epidemiology of episodic adenolymphangitis: a longitudinal prospective surveillance among a rural community endemic for bancroftian filariasis in coastal orissa, india.the epidemiological knowledge on acute condition of lymphatic filariasis is essential to understand the burden and issues on management of the disease.200515904537
age-dependent prevalence of asymptomatic amicrofilaraemic individuals in a wuchereria bancrofti-endemic region of india.the age-related prevalence of asymptomatic amicrofilaraemics, apparently uninfected individuals, was determined in a wuchereria bancrofti-endemic region of orissa, india during 2001. the prevalence of these uninfected individuals was highest in the younger age groups (aged < or = 15 years), decreased rapidly in those aged > 15 to 40 years, and then stabilized in those aged > 40 years.200315228245
parasite antigenaemia and igg4 antibodies to a filarial protease in an endemic human population in india.levels of circulating filarial antigen (og4c3) and igg4 antibodies to a filarial protease were determined in subjects of wuchereria bancrofti exposed sera from orissa, india. in addition to all individuals with antigenaemia (microfilaraemia), igg4 antibodies were also detected in some individuals without antigenaemia. a 2-year longitudinal follow-up indicated that igg4 seropositivity in asymptomatic amicrofilaraemics could be a risk factor for acquiring infection (antigenaemia).200314627443
antigenemia at 10 years after diethylcarbamazine treatment of asymptomatic microfilaraemic individuals: marginal conversion to infection-free state.a group of asymptomatic microfilaraemic individuals (n = 44, 29 males, 15 females) living in a wuchereria bancrofti endemic region of orissa, india, was treated with a standard regimen of diethylcarbamazine (12 days, 6 mg/kg) in 1990. the incidence of microfilaraemia and antigenemia (og4c3) was determined after a gap of 10 years in 2000. nineteen individuals reacquired microfilariae (43.2%, 11 males, eight females), five males developed hydrocele, two females became acute filarial patients and 1 ...200211874566
a randomized controlled trial of increased dose and frequency of albendazole with standard dose dec for treatment of wuchereria bancrofti microfilaremics in odisha, india.although current programmes to eliminate lymphatic filariasis have made significant progress it may be necessary to use different approaches to achieve the global goal, especially where compliance has been poor and 'hot spots' of continued infection exist. in the absence of alternative drugs, the use of higher or more frequent dosing with the existing drugs needs to be explored. we examined the effect of higher and/or more frequent dosing with albendazole with a fixed 300 mg dose of diethylcarba ...201525781977
bancroftian filariasis: a 13-year follow-up study of asymptomatic microfilariae carriers and endemic normals in orissa, india.the natural history of human filarial infections leading to development of disease has been a subject of intense debate. the models proposed so far have largely been based on cross-sectional data on microfilariae (mf) and disease prevalence in filariasis endemic areas. in an attempt to study the parasitological and clinical consequences of filarial infection in beldal (orissa, india), an area endemic for bancroftian filariasis, cohorts of 59 asymptomatic mf carriers (as) and 187 asymptomatic and ...200211862995
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