Publications

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a study of the age-composition of natural populations of culex pipiens fatigans wiedemann in relation to the transmission of filariasis due to wuchereria bancrofti (cobbold) in ceylon.filariasis due to wuchereria bancrofti is becoming an increasingly important problem in many countries of southern and south-eastern asia. from 1962 to 1964, a study was made of the vector of this disease, culex pipiens fatigans, in two districts of colombo, ceylon, one with vector control by larviciding and one without. catches were made of the house-resting, biting and ovipositing populations, and the stages of ovarian development, parity and infection were determined by examination of the ext ...19675300045
efficacy of a limb-care regime in preventing acute adenolymphangitis in patients with lymphoedema caused by bancroftian filariasis, in colombo, sri lanka.the efficacy of a programme of community home-based care (chbc) for lymphoedematous limbs was evaluated among 163 lymphoedema patients attending two filariasis clinics in colombo. each patient was interviewed and examined and his or her lymphoedema was graded during a baseline assessment, before the chbc programme, and again, during a post-intervention assessment, after the patient had been in the programme for 1 year. the number of patients having entry lesions was 24% lower at the post-interve ...200717716431
epidemiology of bancroftian filariasis in three suburban areas of matara, sri lanka.the epidemiological parameters of bancroftian filariasis were investigated in three suburbs of matara, within the south-western coastal belt of sri lanka where the disease is endemic. the overall prevalence of microfilaraemia and the geometric mean density of the microfilaraemias observed were 4.4% and 20.6 microfilariae/60 microl fingerprick blood, respectively. prevalence was significantly lower in the female subjects than in the male, and in males aged < 20 years than in older males. overall, ...200111339886
"primary" pulmonary hypertension, eosinophilia, and filariasis in ceylon.;primary' pulmonary hypertension, which is rare in western countries, was found to be relatively common in ceylon. the clinical and haemodynamic features were studied. there were two distinct types of the disease, malignant and benign. patients with the malignant form of the disease had a rapidly progressive illness of short duration and an invariably fatal outcome. those with the benign form gave a long history and, in spite of severe pulmonary hypertension, were only slightly disabled. they se ...19705433314
loss of filarial larvae in a natural mosquito population.analysis of log normal parasite densities of wuchereria bancrofti in the mosquito culex pipiens fatigans collected in the suburbs of colombo, sri lanka, has shown a decreasing parasite load with age of infection. the median density of microfilarial intake in the natural population was 10.3, but this had decreased to 2.6 by the infective stage. of the total microfilariae ingested, 51.9% were found in the thorax 12--17 hours after infection of the mosquitoes in the laboratory. further decrease in ...1978367299
evaluation of the ict whole-blood antigen card test to detect infection due to wuchereria bancrofti in sri lanka.the sensitivity, specificity and cost effectiveness of an immunochromatographic card test (ict, amrad) for the diagnosis of bancroftian filariasis were estimated against 2 standard parasitological techniques: thick blood film (tbf) and nuclepore membrane filtration (nmf). individuals were selected from endemic localities in the western province (n = 213) and from the non-endemic central province (n = 29) of sri lanka. blood was collected between 21:00 and midnight. sixty microlitre of non-hepari ...200211925995
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