| a longitudinal study of bancroftian filariasis in the nile delta of egypt: baseline data and one-year follow-up. | we initiated a longitudinal study of bancroftian filariasis to improve understanding of dynamics and risk factors for infection in villages near cairo, egypt. baseline prevalence rates for microfilaremia and filarial antigenemia for 1,853 subjects more than 9 years of age were 7.7% and 11.2%, respectively. microfilaria counts, antigen levels, and microfilaremia incidence over a 1-year period were all significantly lower in older people. these findings suggest that humans develop partial immunity ... | 1999 | 10432056 |
| efficient assessment of filariasis endemicity by screening for filarial antigenaemia in a sentinel population. | we have previously reported that a monoclonal antibody-based antigen detection assay (ad12) is sensitive and specific for bancroftian filariasis in egypt. the purpose of the present study was to demonstrate the use of this assay in a sentinel population as a means of efficiently screening for filariasis endemicity. antigen testing was performed with finger-prick blood collected during the day from 743 schoolchildren (ages 11-16 years). the school draws students from 5 villages in qalubia governo ... | 1994 | 8153997 |
| evaluation of a monoclonal-antibody based antigen assay for diagnosis of wuchereria bancrofti infection in egypt. | conventional methods for diagnosis of wuchereria bancrofti infection are insensitive and often impractical because of the need for night blood collections. a sensitive and specific antigen detection assay has been developed for w. bancrofti, which is based on a monoclonal antibody (ad12) that binds to a repeated epitope on a 200 kda adult worm excretion product present in sera from infected humans. the only formal evaluation of this assay to date was performed with sera from india. in the presen ... | 1991 | 1858970 |