evaluation of the micro enzyme-linked immunosorbent assay (elisa) for antibodies in american visceral leishmaniasis: antigen selection for detection of infection-specific responses. | this study was designed to evaluate the elisa for diagnosis of american visceral leishmaniasis (avl) using antigen prepared from different leishmania isolates and from a strain of trypanosoma cruzi. two leishmania donovani chagasi isolates from bahia and maranhão (both states of northern brazil), one l. donovani from sudan, one l. mexicana amazonensis isolate, and one t. cruzi isolate were used. a total of 375 sera were tested, including 119 from avl patients, 96 from nonleishmaniasis hospitaliz ... | 1986 | 3080918 |
leishmaniasis in brazil. xxii: characterization of leishmania from man, dogs and the sandfly lutzomyia longipalpis (lutz & neiva, 1912) isolated during an outbreak of visceral leishmaniasis in santarém, pará state. | during epidemiological studies on an outbreak of visceral leishmaniasis in santarém, pará state, north brazil, isolates of leishmania from two children, three dogs and six naturally infected specimens of the sandfly lutzomyia longipalpis were compared, biochemically, by starch-gel enzyme electrophoresis. they have proved to be indistinguishable from each other, and from a reference strain of leishmania chagasi cunha & chagas, 1937 from a case of human visceral leishmaniasis from bahia state, nor ... | 1986 | 3726975 |
leishmaniasis in brazil. xxi. visceral leishmaniasis in the amazon region and further observations on the role of lutzomyia longipalpis (lutz & neiva, 1912) as the vector. | further evidence is presented incriminating the sandfly lutzomyia longipalpis as the vector of leishmania chagasi, the causative agent of american visceral leishmaniasis, in the amazon region of brazil. during an outbreak of the disease in santarém, pará state, this insect was shown to be the only species of sandfly consistently present in and around the patient's homes, where it often occurred in very large numbers. of 491 specimens dissected, 35 (7.14%) proved to be infected, and isolates of l ... | 1985 | 4002291 |
leishmaniasis in brazil: xviii. further evidence incriminating the fox cerdocyon thous (l) as a reservoir of amazonian visceral leishmaniasis. | major endemic areas of visceral leishmaniasis in brazil are located in the drier, poorly forested regions, principally in the northeastern states such as ceará and bahia. cases of the human disease in the amazon region are rare, very sporadic, and seldom present opportunities for epidemiological study. following the report of a fatal case near salvaterra, the island of marajó, pará state, a preliminary investigation has resulted in the isolation of a parasite regarded as leishmania donovani chag ... | 1982 | 7164150 |
familial aggregation of leishmania chagasi infection in northeastern brazil. | a sample of 1,604 individuals belonging to 243 nuclear families from an endemic area of visceral leishmaniasis (jacobina, bahia state, brazil) was studied to disclose the intrafamilial pattern of infection. significant father to offspring, mother to offspring, and sibling to sibling associations, in contrast a with nonsignificant father to mother association, clearly indicate a familial aggregation of the infection, with a strong suggestion of at least partial genetic involvement. | 1995 | 7741179 |
a cross-sectional serodiagnostic survey of canine leishmaniasis due to leishmania chagasi. | jequie, a community of about 144,500 inhabitants located in the state of bahia, brazil, is endemic for both visceral and cutaneous leishmaniases. in the present epidemiologic study, the urban and inhabited periurban areas of the town were divided into 140 clusters of 0.25 km2 each. the seroprevalence of canine leishmania antibodies was investigated using an enzyme-linked immunosorbent assay as a screening test since its sensitivity was significantly higher than that of an indirect immunofluoresc ... | 1996 | 8702020 |
ecological interactions of visceral leishmaniasis in the state of bahia, brazil. | the laboratory and field observations summarized in this paper on visceral leishmaniasis ecology in the state of bahia, brazil are based on the author's observations over the past 35 years in a number of state's foci, public health records and literature citations. the disease is endemic with epidemic outbreaks occurring every ten years and its geographical distribution is expanding rapidly in the last years. leishmania chagasi is the main ethiologic agent of the visceral leishmaniasis but le. a ... | 1996 | 9283643 |
ecological niche modeling for visceral leishmaniasis in the state of bahia, brazil, using genetic algorithm for rule-set prediction and growing degree day-water budget analysis. | two predictive models were developed within a geographic information system using genetic algorithm rule-set prediction (garp) and the growing degree day (gdd)-water budget (wb) concept to predict the distribution and potential risk of visceral leishmaniasis (vl) in the state of bahia, brazil. the objective was to define the environmental suitability of the disease as well as to obtain a deeper understanding of the eco-epidemiology of vl by associating environmental and climatic variables with d ... | 2006 | 18686237 |
serological survey of leishmania infection in blood donors in salvador, northeastern brazil. | visceral leishmaniasis is endemic to brazil, where it is caused by leishmania infantum (syn. leishmania chagasi). following parasite inoculation, individuals may experience asymptomatic infection, raising the possibility of parasite transmission through the transfusion of contaminated blood products. in the present work, we evaluated the prevalence of asymptomatic leishmania infection among blood donors in salvador, northeastern brazil. | 2014 | 25073468 |