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distribution of phlebotomine sand flies (diptera: psychodidae) in the state of rio grande do norte, brazil.visceral and cutaneous leishmaniasis are major endemic diseases in northeast brazil. the objective of the current study was to determine the species and geographic distribution of potential sand fly vectors of leishmania in the state of rio grande do norte. sand flies were captured using cdc light traps in 30 municipalities distributed throughout the 8 geographic zones of the state. twelve lutzomyia species were identified. lutzomyia longipalpis lutz & neiva was the most prevalent and accounted ...200015218921
an emerging peri-urban pattern of infection with leishmania chagasi, the protozoan causing visceral leishmaniasis in northeast brazil.peri-urban visceral leishmaniasis (vl) caused by leishmania chagasi is emerging in a new epidemiologic pattern in brazilian cities. we studied peri-urban vl in endemic neighborhoods surrounding natal, brazil, identified through hospitalized individuals with vl. clinical and environmental information obtained for 1106 members of 216 families living in endemic neighborhoods enabled us to identify 4 groups: vl: individuals with current or prior symptomatic visceral leishmaniasis (n = 135); dth+: in ...200415307565
genetic predisposition to self-curing infection with the protozoan leishmania chagasi: a genomewide scan.the protozoan leishmania chagasi can cause disseminated, fatal visceral leishmaniasis (vl) or asymptomatic infection in humans. we hypothesized that host genetic factors contribute to this variable response to infection. a family study was performed in neighborhoods of endemicity for l. chagasi near natal in northeastern brazil. study subjects were assessed for the presence of vl or asymptomatic infection, which was defined by a positive delayed-type hypersensitivity (dth) skin test response to ...200717955446
vertical stratification and development aspects of phlebotomine sand flies (diptera: psychodidae) in an area of atlantic forest tree species in a metropolitan region in northeastern brazil.in the state of rio grande do norte in northeast brazil, cases of visceral leishmaniasis (vl) occur mainly in the periurban areas of the city of natal. lutzomyia longipalpis lutz & neiva 1912 (diptera: psychodidae), a vector of leishmania chagasi (protozoa: trypanosomatidae) to humans, is found throughout the state. flora and fauna influence the distribution of sand fly species, whose horizontal or vertical stratification can be used as a parameter for identifying potential vectors, considering ...200718260526
genetic admixture in brazilians exposed to infection with leishmania chagasi.visceral leishmaniasis (vl) in northeast brazil is a disease caused by infection with the protozoan leishmania chagasi. infection leads to variable clinical outcomes ranging from asymptomatic infection to potentially fatal disease. prior studies suggest the genetic background of the host contributes to the development of different outcomes after infection, although it is not known if ancestral background itself influences outcomes. vl is endemic in peri-urban areas around the city of natal in no ...200919397557
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