| surveillance of lyme disease in the united states, 1982. | lyme disease is a tick-borne illness that has been reported from three regions in the united states--the northeast, midwest, and west--which correspond to the distribution of the recognized vectors of the disease, ixodes dammini and ixodes pacificus. in 1982, a surveillance system designed to define the morbidity and geographic distribution for lyme disease by using a clinical case definition received information on 491 definite cases and 38 probable cases. of the definite cases, 489 were acquir ... | 1985 | 3998509 |
| serological responses in lyme disease: the influence of sex, age, and environment. | in the laboratory, the serodiagnosis of lyme disease is a difficult decision, especially in early disease. the variability in the immune response to the borrelia burgdorferi spirochete and the lack of specificity and sensitivity of commercial assays for the detection of antibodies in early disease have contributed to the difficulty of serodiagnosis. this study examines the serological data of over 20,000 serum specimens submitted for enzyme linked immunosorbent assay (elisa) and/or western blot ... | 1993 | 8323257 |
| canine exposure to borrelia burgdorferi and prevalence of ixodes dammini (acari: ixodidae) on deer as a measure of lyme disease risk in the northeastern united states. | surveillance programs that identify areas where both the vector (ixodes dammini) and etiologic agent (borrelia burgdorferi) are present may identify the risk of lyme disease and its spread earlier and more accurately than do programs relying on any single method, particularly human case reports. hunter-killed deer (n = 1,204) from 22 counties in maryland, massachusetts, new hampshire, new york, and pennsylvania were examined in fall 1989 and all ectoparasites were identified. the following sprin ... | 1993 | 8433324 |
| hemocytic rickettsia-like organisms in ticks: serologic reactivity with antisera to ehrlichiae and detection of dna of agent of human granulocytic ehrlichiosis by pcr. | ixodid ticks were collected from connecticut, massachusetts, missouri, pennsylvania, rhode island, and british columbia (canada) during 1991 to 1994 to determine the prevalence of infection with hemocytic (blood cell), rickettsia-like organisms. hemolymph obtained from these ticks was analyzed by direct and indirect fluorescent antibody (fa) staining methods with dog, horse, or human sera containing antibodies to ehrlichia canis, ehrlichia equi, or rickettsia rickettsii. of the 693 nymphal and a ... | 1995 | 8567911 |
| molecular characterization of anaplasma phagocytophilum and borrelia burgdorferi in ixodes scapularis ticks from pennsylvania. | ixodes scapularis ticks were collected in 2000 and 2001 from two areas in pennsylvania and tested for the presence of anaplasma phagocytophilum and borrelia burgdorferi by pcr and dna sequencing. of the ticks collected from northwestern and southeastern pennsylvania, 162 of 263 (61.6%) and 25 of 191 (13.1%), respectively, were found to be positive for b. burgdorferi. dna sequencing showed >99% identity with b. burgdorferi strains b31 and jd1. pcr testing for a. phagocytophilum revealed that 5 of ... | 2003 | 12682147 |
| characterization of anaplasma phagocytophila and borrelia burgdorferi genotypes in ixodes scapularis ticks from pennsylvania. | | 2003 | 12860614 |
| new ruminant hosts and wider geographic range identified for babesia odocoilei (emerson and wright 1970). | babesia odocoilei was found to infect two previously unknown host species, desert bighorn sheep (ovis canadensis nelsoni) and musk oxen (ovibos moschatus), both of which are members of the family bovidae. previously, b. odocoilei has been reported in only cervidae hosts. new geographic regions where b. odocoilei infections have not been reported previously include pennsylvania and new york, where fatal babesiosis has occurred in reindeer (rangifer tarandus tarandus); new hampshire, where elk (ce ... | 2005 | 16456156 |
| infection and co-infection rates of anaplasma phagocytophilum variants, babesia spp., borrelia burgdorferi, and the rickettsial endosymbiont in ixodes scapularis (acari: ixodidae) from sites in indiana, maine, pennsylvania, and wisconsin. | in total, 394 questing adult blacklegged ticks, ixodes scapularis say (acari: ixodidae), collected at four sites were analyzed by polymerase chain reaction (pcr) for five microbial species: anaplasma phagocytophilum, babesia microti, babesia odocoilei, borrelia burgdorferi, and the rickettsial i. scapularis endosymbiont. identities of genetic variants of a. phagocytophilum were determined by sequencing a portion of the 16s dna. in 55% of infected ticks (193/351), a single agent was detected. in ... | 2008 | 18402145 |
| surveillance for lyme disease--united states, 1992-2006. | lyme disease is a multisystem disease that occurs in north america, europe, and asia. in the united states, the etiologic agent is borrelia burgdorferi sensu stricto, a spirochete transmitted to humans by infected ixodes scapularis and i. pacificus ticks. the majority of patients with lyme disease develop a characteristic rash, erythema migrans (em), accompanied by symptoms of fever, malaise, fatigue, headache, myalgia, or arthralgia. other manifestations of infection can include arthritis, card ... | 2008 | 18830214 |