| surveillance for lyme disease--united states, 1992-2006. | lyme disease is a multisystem disease that occurs in north america, europe, and asia. in the united states, the etiologic agent is borrelia burgdorferi sensu stricto, a spirochete transmitted to humans by infected ixodes scapularis and i. pacificus ticks. the majority of patients with lyme disease develop a characteristic rash, erythema migrans (em), accompanied by symptoms of fever, malaise, fatigue, headache, myalgia, or arthralgia. other manifestations of infection can include arthritis, card ... | 2008 | 18830214 |
| borrelia burgdorferi and the causative agent of human granulocytic ehrlichiosis in deer ticks, delaware. | during the 1998 hunting season in delaware, 1,480 ticks were collected from 252 white- tailed deer; 98% were ixodes scapularis, a significant increase from the 85% reported in 1988. ticks were tested for borrelia burgdorferi and the causative agent of human granulocytic ehrlichiosis. infection rates remained stable in new castle and kent counties, but increased from <1% to 8% in sussex county. | 2000 | 10905979 |
| serological responses in lyme disease: the influence of sex, age, and environment. | in the laboratory, the serodiagnosis of lyme disease is a difficult decision, especially in early disease. the variability in the immune response to the borrelia burgdorferi spirochete and the lack of specificity and sensitivity of commercial assays for the detection of antibodies in early disease have contributed to the difficulty of serodiagnosis. this study examines the serological data of over 20,000 serum specimens submitted for enzyme linked immunosorbent assay (elisa) and/or western blot ... | 1993 | 8323257 |