| new delhi metallo-ss-lactamase-1: local acquisition in ontario, canada, and challenges in detection. | new delhi metallo-ß-lactamase-1 (ndm-1) is a recently identified metallo-ß-lactamase that confers resistance to carbapenems and all other ß-lactam antibiotics, with the exception of aztreonam. ndm-1 is also associated with resistance to many other classes of antibiotics. the enzyme was first identified in organisms isolated from a patient in sweden who had previously received medical treatment in india, but it is now recognized as endemic throughout india and pakistan and has spread worldwide. t ... | 2011 | 21624908 |
| new delhi metallo-beta-lactamase, ontario, canada. | | 2011 | 21291614 |
| detection of plasmid-mediated kpc-producing klebsiella pneumoniae in ottawa, canada: evidence of intrahospital transmission. | klebsiella pneumoniae isolates from three patients admitted to the ottawa hospital, a 1,040-bed teaching hospital, were found to contain the plasmid-borne k. pneumoniae carbapenemase (kpc)-producing bla gene (bla(kpc)). there was evidence of person-to-person transmission for two patients. screening of 186 clinical isolates revealed no additional bla(kpc)-containing isolates. | 2009 | 19357206 |
| transferable antibiotic resistance in e. coli and klebsiella pneumoniae. | twenty-three of 43 e. coli and 25 of 39 klebsiella isolates, resistant to two or more antibiotics, transferred one or more resistance genes to a recipient e. coli k(12) culture. resistances transferred most frequently by both species were those to kanamycin and neomycin. e. coli cultures transferred resistance to tetracycline, chloramphenicol, ampicillin and carbenicillin, whereas klebsiella isolates transferred resistance to the first two of these antibiotics. extrapolation of these results to ... | 1973 | 4583432 |
| plasmid comparison and molecular analysis of klebsiella pneumoniae harbouring bla(kpc) from new york city and toronto. | this study examined klebsiella pneumoniae clinical isolates and their bla(kpc) plasmids to determine potential relatedness of the isolates and their plasmids harbouring carbapenem resistance mechanisms. | 2011 | 21406433 |
| endogenous klebsiella endophthalmitis in a vietnamese immigrant. | | 2009 | 19687101 |
| outbreak of carbapenem-resistant enterobacteriaceae containing blandm-1, ontario, canada. | new delhi metallo-ß-lactamase (ndm) has emerged worldwide in clinically relevant gram-negative bacteria. we report an outbreak of ndm-producing klebsiella pneumoniae in patients with no prior travel history to endemic regions. | 2012 | 22997214 |
| molecular characterization of klebsiella pneumoniae carbapenemase (kpc)-producing enterobacteriaceae in ontario, canada, 2008-2011. | due to the lack of detailed reports of klebsiella pneumoniae carbapenemase (kpc)-producing enterobacteria in ontario, canada, we perform a molecular characterization of kpc-producing enterobacteriaceae submitted to the provincial reference laboratory from 2008 to 2011. susceptibility profiles were accessed by e-test. molecular types of isolates were determined by pulse-field gel electrophoresis (pfge) and multilocus sequence typing. screening of ß-lactamase genes was performed by multiplex pcr a ... | 2014 | 25549365 |