| the oh-/h+ concept of acid-base balance: historical development. | | 1978 | 27858 |
| abstracts. renal association, london, england, october 1977 and february 1978. | | 1978 | 31509 |
| open ward versus rabbit warren. | | 1978 | 249517 |
| heberden oration 1978. recent studies on the control of joint damage: the contribution of the strangeways research laboratory. | | 1979 | 485574 |
| medical staff conference: recent chapters in the factor viii saga--perils of a protein. fifth annual paul m. aggeler memorial lecture. | | 1975 | 1079388 |
| survey of prothrombin time in national external quality assessment scheme exercises (1980-87). | national external quality assessment scheme surveys on the prothrombin time test carried out in hospitals in the united kingdom have been performed at regular intervals since 1972. performance has been assessed by comparing observed variability between hospitals with that predicted by a statistical model. the model was based on results from 53 survey plasmas issued between 1980 and 1987. these showed a linear correlation between logarithms of mean and standard deviation of reported ratios. preci ... | 1988 | 3366918 |
| a reappraisal of the role of mosquitoes in the transmission of myxomatosis in britain. | field experiments were made in southern england to re-examine the possibility that mosquitoes in britain might feed on wild rabbits and hence be vectors of myxomatosis. mosquitoes of several species were attracted to rabbits enclosed in cylindrical traps and in a trap in which the animal was placed in a wire mesh cage. substantial numbers of mosquitoes were also caught biting, or attempting to bite, tethered rabbits which were not in cages or traps. evidence that mosquitoes fed on wild rabbits u ... | 1971 | 4401995 |
| a. e. barclay and angiographic research in oxford. | | 1988 | 3064857 |
| a survey of rhizobia in farm soils at wye college, kent. | | 1972 | 4623604 |
| possible windborne spread of myxomatosis to england in 1953. | an analysis of the meterological conditions showed that the first outbreaks of myxomatosis in s.e. england in 1953 could have resulted from wind carriage of insects infected with myxoma virus from northern france. south-easterly winds on the night 11-12 august would have carried the insects 120-160 km from the départements of nord, pas de calais and somme across the english channel to near edenbridge, kent. the flight would have taken 6.5-8.5 h at wind speeds of 15-22 km h-1. on the night 11-12 ... | 1987 | 2881798 |
| myxomatosis in farmland rabbit populations in england and wales. | the overall pattern and consequences of myxomatosis in wild rabbit populations were studied at three farmland sites in lowland southern england and upland central wales between 1971 and 1978. when results from all years were combined, the disease showed a clear two-peaked annual cycle, with a main autumn peak between august and january, and a subsidiary spring peak during february to april. rabbit fleas, the main vectors of myxomatosis in britain, were present on full-grown rabbits in sufficient ... | 1989 | 2806418 |
| m. xenopei: a bacteriological study of m. xenopei including case reports of danish patients. | | 1967 | 4860136 |
| classification of mycobacterium avium and related opportunist mycobacteria met in england and wales. | | 1967 | 4864326 |
| characterization of cross-reacting serotypes of campylobacter jejuni. | some strains of campylobacter jejuni react with more than one reference antiserum from the serotyping scheme based on heat-stable lipopolysaccharide antigens. to investigate the molecular basis of these cross-reactions, lipopolysaccharides from the reference strains for serotypes 4, 13, 16, 43, and 50 and isolates recovered during two different outbreaks of c. jejuni enteritis were analyzed by passive haemagglutination and sodium dodecyl sulphate-polyacrylamide gel electrophoresis coupled with s ... | 1989 | 2472859 |
| about boxing: review of historical and medical aspects. | | 1970 | 4995464 |
| possible host specificity of cheyletiella mites. | | 1972 | 5049999 |
| scrapie-like encephalopathy in a greater kudu (tragelaphus strepsiceros) which had not been fed ruminant-derived protein. | a 19-month-old greater kudu (tragelaphus strepsiceros), whose dam had died 15 months earlier with spongiform encephalopathy, required euthanasia after developing severe ataxia and depression with an apparently sudden onset. no macroscopic abnormalities were detected on post mortem examination but a scrapie-like spongiform encephalomyelopathy was apparent on histopathological examination of brain and segments of spinal cord. negative stain electron microscopy of proteinase k-treated detergent ext ... | 1992 | 1604783 |
| demonstration of serum albumin (alb) polymorphism in wild rabbits, oryctolagus cuniculus, by means of isoelectric focusing. | genetic polymorphism of serum albumin was demonstrated by isoelectric focusing in wild rabbit populations from portugal and england. gene frequencies were estimated to be (1) alb*1 = 0.47, alb*2 = 0.49, alb*3 = 0.04, in portugal, and (2) alb*1 = 0.60 and alb*2 = 0.40, in england. one hundred portuguese domestic rabbits of mixed breeds were all of alb 1 type. | 1992 | 1503263 |
| records of anoplocephaline cestodes from wild rabbits and hares collected throughout great britain. | four species of anoplocephaline cestodes were found in wild rabbits collected throughout britain in 1962 and 1972, i.e; since the great reduction in rabbit numbers following the introduction of myxomatosis, in 1953. they were cittotaenia pectinata (goeze, 1782), c. denticulata (rudolphi, 1804), c. ctenoides (rhiehm, 1881) and andrya cuniculi (blanchard 1891). c. pectinata and c. denticulata were relatively common with a respective prevalence of 25% and 8% in two samples totalling 442 rabbits and ... | 1975 | 1127217 |
| constant region igg allotypes in hares: group e allelic polymorphism. | | 1976 | 939582 |
| factors affecting the outcome of corneal transplantation. | corneal grafting has been attempted for 200 years. greatly improved results in recent years have been attributed to developments in anaesthesia, asepsis, and immunological and anti-inflammatory therapy. the important factors affecting the outcome of corneal grafting today are the degree of vascularisation of the cornea before surgery, the inflammatory status at the time of surgery, and the number of antigenic determinants shared by donor and host. allograft rejection is the most common cause of ... | 1981 | 6166235 |
| alpha chain disease clinicopathological features and relationship to so-called mediterranean lymphoma. | | 1975 | 810151 |
| [recollections on the development of the neurovascular concept of hypothalamo-hypophysial control (author's transl)]. | | 1976 | 798045 |
| the species of eimeria in rabbits for meat production in britain. | eight species of coccidia were recognized in 596 faeces samples from 3 commercial rabbitries in south east england. the level of infection was related to management methods and at one site it was reduced by an outbreak of mucoid enteritis and/or its treatment with oxytetracycline. in samples from rabbits managed conventionally in the wire cages over droppings-pits, 96% contained oocysts and of these, 60% had 1000-10000 oocysts/g. mixed infections were common, 67% of the animals carrying 2-4 diff ... | 1979 | 537836 |
| the optimal therapeutic range in oral anticoagulation. history and proposal. | for patients on oral anticoagulation controlled with quick's prothrombin time test using rabbit brain thromboplastin american clinicians proposed in the early 1940s that the lower limit of prolongation be taken at 1.5 and the upper limit at 3, corresponding to 10-30% prothrombin activity on a saline dilution curve. thromboplastins derived from other tissues and species were later introduced, methods were modified, and adsorbed plasma was used instead of saline in the construction of the dilution ... | 1979 | 396691 |
| ultrastructural changes in the heart at high altitude. | | 1973 | 4578023 |
| innate resistance to myxomatosis in wild rabbits in england. | wild rabbits (oryctolagus cuniculus) from one study area in england have been used over a period of 11 years to investigate the possible appearance of innate resistance to myxomatosis. rabbits of 4-6 weeks old were captured alive, retained in the laboratory until at least 4 months old, and then infected with a type of myxoma virus which kills 90-95% of laboratory rabbits. observations were made of symptoms, mortality rate and survival times.in the first 4 years of the study (1966-9), mortality r ... | 1977 | 270526 |
| influenza a neuraminidase antibodies in children and young adults studied by serum absorption. | a study is described of influenza a anti-neuraminidase antibodies in the sera of young people of three different groups. each serum was individually absorbed with viruses containing the n2 neuraminidases of 1957, 1968 and 1972. rabbit antisera prepared against the viruses were similarly absorbed. results obtained with the animal sera suggested that these neuraminidases were antigenically distinct, but the human sera had a broader range of anti-neuraminidase activity and gave indication of asymme ... | 1977 | 265343 |
| european brown hare syndrome in england. | the livers from 50 brown hares (lepus europaeus) were examined by electron microscopy for calicivirus-like particles typical of the virus of european brown hare syndrome (ebhs). the virus was visible in 23 of the livers which included four taken from hares which died in 1982 and 1985 and which had been stored at -20 degrees c. the clinical histories, post mortem and other findings associated with these 23 hares were similar to those described in cases of european brown hare syndrome in other eur ... | 1994 | 7941275 |
| [pathobiology of carcinogenesis and the growth of neoplasms]. | the importance of carcinogenicity by chemical substances is reviewed with regard to the increasing number of human neoplasms (1955: 39703; 1972: 62556) in the german democratic republic. the organotropic action of some carcinogens, the transplacental tumour induction, the endogenous formation of oncogenic n-nitroso compounds from inactive precursors in the stomach of experimental animals, and the role of carcinogens derived from plants are analysed. up to now it remains uncertain, whether dna an ... | 1975 | 132065 |
| abstracts of papers presented at a meeting of the british microcirculation society. april 6 and 7, 1979, st. george's hospital medical school, london, england. | | 1979 | 40098 |
| royal society of tropical medicine and hygiene, brunel university school of biological sciences 20th april, 1978. abstracts. | | 1979 | 35867 |
| a two-year study of the distribution of 'thermophilic' campylobacters in human, environmental and food samples from the reading area with particular reference to toxin production and heat-stable serotype. | the incidence of 'thermophilic' campylobacters in foods and environmental samples has been studied over a two-year period. of 781 environmental samples, 529 (67%) were found to contain campylobacters, and campylobacters were isolated from 835 (39%) of 2116 food samples. sewage was almost always contaminated with campylobacters (96.6% of samples) and of the food samples both poultry (55.5%) and offal (47.0%) were commonly contaminated. determination of the heat-stable serotypes of all strains iso ... | 1989 | 2753842 |
| serotyping scheme for campylobacter jejuni and campylobacter coli based on direct agglutination of heat-stable antigens. | campylobacter is now the most frequently reported cause of gastrointestinal disease in england and wales, yet few isolates are characterized beyond the genus level. the majority of isolates are campylobacter jejuni (90%), with most of the remainder being campylobacter coli. we describe an adaptation of the penner serotyping scheme in which passive hemagglutination has been replaced by detection of heat-stable antigens by direct bacterial agglutination; absorbed antisera are used where appropriat ... | 1998 | 9466737 |
| correspondence: conducting research with laboratory animals. | | 1974 | 4446313 |
| the plague's last visit? | | 1970 | 4190364 |
| howard florey. | | 1998 | 9785528 |
| plasma immunoglobulin concentrations in a west african (gambian) community and in a group of healthy british adults. | | 1968 | 4171047 |
| radio-iodine in thyroid glands of swans, farm animals and humans, also in algae and river water from the thames valley, england. | a highly sensitive counting system has been used to measure radio-iodine in environmental samples from the thames valley. iodine-125 and occasionally iodine-131 have been found in the thyroid glands of most of the swans that have died on the river thames, the river wey and the grand union canal, and in algae and water samples from the thames and many of its tributaries. the presence of this activity is ascribed to the waste discarded into the drainage system by hospitals and research laboratorie ... | 1986 | 3945795 |
| staphylococcosis in a commercial rabbitry. | | 1986 | 3776074 |
| toxoplasmosis in england. i. the rabbit (oryctolagus cuniculus) as a host of toxoplasma gondii. | | 1955 | 13283508 |
| tuberculosis in east sussex. iv. a systematic examination of wild mammals other than badgers for tuberculosis. | a detailed investigation of the possible role of wild mammals, other than badgers, in the maintenance of mycobacterium bovis in an area on the south downs of east sussex was carried out over 3 years. estimates of population sizes were made where possible and minimum sample sizes were selected to be 95% certain of including at least one infected animal if the prevalence was at least 5%. samples of wild mammals were taken from populations which had the highest potential direct or indirect contact ... | 1986 | 3525673 |
| a historical perspective of renal transplantation. | | 1979 | 399512 |
| some observations on the use of the quchterlony gel diffusion technique in the study of myxomatosis. | | 1963 | 14066594 |
| serologic studies of some porcine enteroviruses by means of neutralization tests in tissue culture. | | 1964 | 14125909 |
| further observations on antibacterial immunity to staphylococcus pyogens in rabbits. | | 1964 | 14173168 |
| the incidence of the serological groups of candida albicans in southern england. | | 1964 | 14210787 |
| an outbreak of myxomatosis caused by a moderately attenuated strain of myxoma virus. | | 1964 | 14239923 |
| serological characterization of group-a streptococci associated with skin sepsis in meat handlers. | a series of outbreaks of skin sepsis among meat handlers in england during 1974 and 1975 afforded an opportunity to study the group-a streptococci commonly isolated from the lesions. few of these streptococci could be m typed with existing antisera. intensive study of strains from two outbreaks of sepsis in one abattoir in shropshire led to the recognition of three new provisional m types. the streptococci were first sorted according to t-typing pattern and ability to produce opacity factor. op ... | 1977 | 321678 |
| yamagiwa's tar cancer and its historical significance. from percival pott to katsusaburo yamagiwa. | | 1968 | 4889459 |
| relationship between aeroallergen and food allergen sensitization in childhood. | previous studies measuring the prevalence of allergen sensitization have been relatively small and used small numbers of allergens. to effectively evaluate children with atopic disease, we need an accurate knowledge of which allergens are important. | 2005 | 16008681 |
| rheumatoid factors in families. | | 1973 | 4584529 |
| the carotid bodies in animals at high altitude. | | 1973 | 4718568 |
| blowfly strike in rabbits. | | 2006 | 16766732 |
| helminth parasites of the wild rabbit oryctolagus cuniculus (l.) in north east england. | | 1972 | 5064541 |
| detection of human metapneumovirus in respiratory secretions by reverse-transcriptase polymerase chain reaction, indirect immunofluorescence, and virus isolation in human bronchial epithelial cells. | over two winters in newcastle upon tyne, respiratory secretions, negative by immunofluorescence staining for other respiratory viruses, were tested for the presence of human metapneumovirus (hmpv) by rt-pcr. in the second winter, specimens were also tested by immunofluorescence staining with an anti-hmpv polyclonal rabbit antiserum and immunofluorescence positive specimens were inoculated into a line of human bronchiolar cells, 16hbe140. overall, 55 of 549 (10%) specimens tested were positive fo ... | 2006 | 16847967 |
| proceedings of the first international conference for the standardisation of banded karyotypes of domestic animals. university of reading reading, england. 2nd-6th august 1976. | | 1980 | 6103884 |
| 99mtc-colloid kits from the view point of the accretion in the bone marrow--with special reference to comparison with 198au-colloid. | with 9 kinds of available 99mtc-colloid kits for res imaging, especially from the aspect of res imaging of the bone marrow, observations were conducted on ph, the presence of free 99mtco4(-), labelling efficiency, rabbit blood clearance, the uptake in res, urinary excretion, as well as the scintigraphy with rabbits and clinical cases. compared to 198au-colloid, marrow to liver ratio was found to be about the same, but its uptake to the spleen and liver was greater. in particular its urinary excr ... | 1980 | 6249599 |
| the incidence of anoplocephaline cestodes in a population of rabbits in surrey, england. | | 1973 | 4761774 |
| thromboplastin reference preparations. | the need for standardization of methods for the control of anticoagulant therapy was apparent 25 years ago. with the development of the ratio method for comparing the sensitivity of different thromboplastin preparations it became possible to equate the value obtained with one preparation in terms of the value which would be obtained with any other preparation, and the need for a reference to serve as a yardstick for comparison became obvious. the first trial reference preparation was developed i ... | 1980 | 6941441 |
| molecular epidemiology of campylobacter jejuni populations in dairy cattle, wildlife, and the environment in a farmland area. | we describe a cross-sectional study of the molecular epidemiology of campylobacter jejuni in a dairy farmland environment, with the aim of elucidating the dynamics of horizontal transmission of c. jejuni genotypes among sources in the area. a collection of 327 c. jejuni isolates from cattle, wildlife, and environmental sources in a 100-km(2) area of farmland in northwest england was characterized by multilocus sequence typing. a total of 91 sequence types and 18 clonal complexes were identified. ... | 2008 | 18586964 |
| an historical look at embryo transfer. | | 1981 | 7014855 |
| the development of genetic resistance to myxomatosis in wild rabbits in britain. | the presence of genetic resistance to myxomatosis in a sample of wild rabbits from one area in england was reported in 1977. rabbits from three other areas in great britain have been tested subsequently, and all cases showed similar resistance to a moderately virulent strain of myxoma virus. rabbits from one area also showed a significant degree of resistance to a fully virulent strain of virus. it is concluded that genetic resistance to myxomatosis is widespread in wild rabbit populations in br ... | 1984 | 6736637 |
| allergy to laboratory animals: a follow up study of its incidence and of the influence of atopy and pre-existing sensitisation on its development. | to investigate the incidence of allergy to laboratory animals (ala) during the first two years of employment, and to study the effect on ala of atopy and sensitisation. | 1995 | 7757166 |
| cryptosporidium sp. rabbit genotype, a newly identified human pathogen. | | 2009 | 19402985 |
| investigation of farms linked to human patients with cryptosporidiosis in england and wales. | the study investigates farms suspected of being sources of zoonotic human cryptosporidiosis. a variety of implicated farm animal species were sampled and tested to detect cryptosporidium oocysts and investigate genetic linkage with human patients. risk factor information was collected from each farm and analysed by multivariable logistic regression to detect significant associations between factors and cryptosporidium in animals. the results showed that average sample prevalence of cryptosporidi ... | 2010 | 20096944 |
| possible origin of rabbit haemorrhagic disease in the united kingdom. | rabbit haemorrhagic disease was reported for the first time in the united kingdom in 1992, and there followed four further small localised outbreaks, all in the south of england. investigation has revealed no definitive mechanism for the introduction of the disease but it is considered that it probably originated from the near continent. the possibility of the transmission of the virus across the channel by aerosol, birds and south coast ferry traffic is discussed, particularly with respect to t ... | 1994 | 7871688 |
| contractility of lungs and air-tubes: experiments performed in 1840 by charles j.b. williams. | in the 18th century, some medical practitioners considered the main pathological feature of asthma to be the production of mucus. later, during the 19th century, airway smooth muscle contraction was recognized to be a possible cause of airflow obstruction. however, not until 1840 was the contractility of airway smooth muscle clearly established by charles j.b. williams, a famous london physician. in a number of innovative experiments in dogs, rabbits, livestock and even donkeys, he showed: 1) th ... | 1994 | 8013615 |
| [the woman who gave birth to rabbits]. | | 1998 | 9715080 |
| a serological study of canine herpes virus-1 infection in the english dog population. | an epidemiological survey investigated the prevalence of canine herpes virus-1 antibodies in a population of 325 pet dogs in england. sera were analysed for the presence of canine herpes virus-1 neutralising antibody by means of a serum neutralisation test and for virus-specific igg and igm by means of enzyme-linked immunosorbent assays. in contrast with published results from other parts of the world, canine herpes virus-1 infection was shown to be common among the domestic dog population of en ... | 1998 | 9739327 |
| the carotid body in animals at high altitude. | | 1971 | 5135659 |
| characterization of paub, a novel broad-spectrum plasminogen activator from streptococcus uberis. | a bovine plasminogen activator of atypical molecular mass ( approximately 45 kda) from streptococcus uberis strain sk880 had been identified previously (l. b. johnsen, k. poulsen, m. kilian, and t. e. petersen. infect. immun. 67:1072-1078, 1999). the strain was isolated from a clinical case of bovine mastitis. the isolate was found not to secrete paua, a bovine plasminogen activator expressed by the majority of s. uberis strains. analysis of the locus normally occupied by paua revealed an absenc ... | 2002 | 11741851 |
| validation of serological correlate of protection for meningococcal c conjugate vaccine by using efficacy estimates from postlicensure surveillance in england. | meningococcal c conjugate (mcc) vaccines were licensed on the basis of serological correlates of protection without efficacy data. the original correlate of protection was established by using a serum bactericidal antibody assay (sba) with human complement (hsba), with titers > or =4 predicting protection. however, the antibody data supporting licensure were largely generated by sba with rabbit complement (rsba), which gives higher titers than hsba. while rsba titers > or =128 reliably predict p ... | 2003 | 12965904 |
| characteristics of clostridium perfringens strains associated with food and food-borne disease. | hall, herbert e. (robert a. taft sanitary engineering center, cincinnati, ohio), robert angelotti, keith h. lewis, and milton j. foter. characteristics of clostridium perfringens strains associated with food and food-borne disease. j. bacteriol. 85:1094-1103. 1963.-a total of 83 strains of clostridium perfringens-30 from england, europe, and asia, associated with food-poisoning outbreaks; 28 from the united states, associated with outbreaks or contaminated foods; and 25 from natural or pathologi ... | 1963 | 14044000 |
| diurnal variation of oral glucose tolerance in volunteers and laboratory animals. | | 1971 | 5560916 |
| genotypic and antibiotic susceptibility characteristics of a campylobacter coli population isolated from dairy farmland in the united kingdom. | campylobacter infections are the most common cause of bacterial enteritis in humans, and nearly 8% of such infections are caused by campylobacter coli. most studies have concentrated on campylobacter jejuni, frequently isolated from intensively farmed poultry and livestock production units, and few studies have examined the spread and relatedness of campylobacter across a range of geographical and host boundaries. systematic sampling of a 100-km2 area of mixed farmland in northwest england yield ... | 2004 | 14766560 |
| what limits herb biomass in grasslands: competition or herbivory? | competition and herbivory are two of the main forces shaping plant communities. although several studies have investigated their impact on plant populations separately, few investigations have examined how they might interact. with the purpose of clarifying the combined roles of competition and herbivory on herb biomass in a grassland, we assessed the effects of different herbivores with reduced grass competition. we conducted a field experiment in 2000-2001 in a british acid grassland (oak mead ... | 2005 | 15480802 |
| seroprevalence of antibodies to encephalitozoon cuniculi in domestic rabbits in the united kingdom. | serum samples from 97 clinically healthy domestic rabbits were tested for antibodies to encephalitozoon cuniculi by an indirect elisa technique. fifty (52 per cent) of them were seropositive. the samples were taken as part of a routine health screen or before general anaesthesia at 22 veterinary practices in england, scotland and wales, and the veterinary surgeons were asked to complete a questionnaire to provide information concerning the animal's husbandry, diet, vaccination, health status and ... | 2006 | 16632526 |
| vascular endothelial growth factor expression in canine intracranial meningiomas and association with patient survival. | vascular endothelial growth factor (vegf) is a regulator of angiogenesis and vascular permeability. in human patients with meningiomas, increased vegf expression is predictive of postsurgical recurrence. the objectives of this study were to evaluate vegf expression in canine intracranial meningiomas and to determine whether an association between vegf expression and patient survival existed. | 2006 | 16734105 |
| blowfly strike prevalence in domestic rabbits in southwest england and wales. | the prevalence of blowfly strike in rabbits in southwest england and wales was investigated using a retrospective postal survey of small animal and mixed veterinary practices. questionnaires were sent to 474 practices; 219 were returned completed, giving a response rate of 46.2%. the prevalence of blowfly strike was estimated as the percentage of veterinary practices that reporting having treated at least one rabbit for strike between may and september 2005. overall, 94.5% (+/-2.21) of practices ... | 2006 | 16822615 |
| wild rabbits (oryctolagus cuniculus) as potential carriers of verocytotoxin-producing escherichia coli. | in summer 2001, visitors to a wildlife park in norfolk, uk, became infected with verocytotoxin-producing escherichia coli (vtec) o157, which was associated with wild rabbit faeces. the rabbits lived in an adjacent field together with e coli o157-positive cattle. a pilot study was therefore performed to investigate the factors affecting the association between e coli o157-positive cattle and wild rabbits. samples of faeces were taken from 16 herds of cattle that lived close to populations of wild ... | 2006 | 16891425 |
| diagnosis of human metapneumovirus by immunofluorescence staining with monoclonal antibodies in the north-east of england. | since its discovery in 2001 human metapneumovirus (hmpv) has been shown to be a significant cause of human respiratory disease, responsible for 5-8% of respiratory infections in hospitalised children. diagnosis hitherto has been largely carried out by reverse tanscriptase polymerase chain reaction (rt-pcr) but immunofluorescence staining of cells from nasopharyngeal secretions (if) offers advantages for some laboratories and may produce a more rapid result in urgent cases. we have recently demon ... | 2007 | 17869169 |
| gastric dilation and intestinal obstruction in 76 rabbits. | eighty-four incidents of gastric dilation (bloat) were investigated in 76 pet rabbits, and an intestinal obstruction was confirmed in 64 of them. in 49 the obstruction was due to pellets of compressed hair, in four to locust bean seeds, in five to neoplasia, in two to postspay adhesions, and in one case each to carpet fibre, tapeworm cysts, a strangulated hernia and diverticulosis. in all but four cases, the obstruction was in the small intestine. the condition affected a variety of breeds fed o ... | 2007 | 17890769 |
| joseph swan (1791-1874): pioneer of research on peripheral nerves. | joseph swan was born in 1791 and appointed surgeon to lincoln county hospital in 1814. in addition to his clinical work, he carried out what were probably the first animal experiments on nerve injuries. these were mostly on rabbits, in which the sciatic nerves were partly or wholly divided, had a section excised, or were ligated. he found that regeneration could occur, even after neurectomy. he reported these results, together with his experience in human patients and the effects of neurectomy i ... | 2008 | 18562353 |
| neospora caninum: detection in wild rabbits and investigation of co-infection with toxoplasma gondii by pcr analysis. | neospora caninum is an important pathogen of cattle causing significant economic loss. there is much current interest in wild animal reservoirs for this parasite. the role of the rabbit in this is currently unknown. dna samples from the brains of wild rabbits (oryctolagus cuniculus) collected from the malham area of the yorkshire dales were investigated by species-specific pcr for the presence of n. caninum and toxoplasma gondii. we found prevalences of n. caninum of 10.5% (6/57) and t. gondii o ... | 2008 | 18703054 |
| tracing the source of campylobacteriosis. | campylobacter jejuni is the leading cause of bacterial gastro-enteritis in the developed world. it is thought to infect 2-3 million people a year in the us alone, at a cost to the economy in excess of us $4 billion. c. jejuni is a widespread zoonotic pathogen that is carried by animals farmed for meat and poultry. a connection with contaminated food is recognized, but c. jejuni is also commonly found in wild animals and water sources. phylogenetic studies have suggested that genotypes pathogenic ... | 2008 | 18818764 |
| myxomatosis in 1950s britain. | in 1953 myxomatosis, a viral disease of rabbits, broke out in britain for the first time. it rapidly killed tens of millions of the animals from kent to the shetlands. many farmers and foresters welcomed a disease that virtually eliminated a longstanding and serious agricultural pest. others were horrified by the sight of thousands of dead and dying animals. with meat still rationed, consumers rued the loss of a cheap and nutritious foodstuff. rough shooters deplored the loss of prey and hatters ... | 2008 | 19069081 |
| rabbit haemorrhagic disease in the united kingdom. | in april 1992, an investigation of sudden, increased mortality among adult rabbits on two premises in the south of england revealed clinical and pathological findings consistent with rabbit haemorrhagic disease. virus particles morphologically resembling caliciviruses were detected in the livers of affected rabbits, and further studies confirmed the first recorded cases of rabbit haemorrhagic disease in the united kingdom. | 1993 | 8128550 |
| moderate reduction of beta-globin gene transcript by a novel mutation in the 5' untranslated region: a study of its interaction with other genotypes in two families. | we have identified two individuals of greek cypriot origin with thalassemia intermedia. molecular analysis has shown that each individual is a compound heterozygote for a previously described beta zero thalassemia allele and a novel mutation, c-->g in position +33, in the 5' untranslated region of the beta globin gene. in both families the beta +33 allele is associated with the same beta haplotype (-++- ) suggesting that it is likely to be of a single origin, beta-cdnas from normal and mutant be ... | 1996 | 8562944 |
| helminth parasites of the wild rabbit oryctolagus cuniculus near malham tarn, yorkshire, uk. | between 1992 and 1996, 95 rabbits from the immediate locality of malham tarn, north yorkshire, uk were examined for the presence of helminth parasites. all the examinations took place in late september or october. three species of nematodes, graphidium strigosum, passalurus ambiguus and trichostrongylus retortaeformis and two species of cestodes, taenia pisiformis and cittotaenia pectinata were identified. there were no associations between helminth species richness and year of sampling, host we ... | 1999 | 10654397 |
| progeria research day at brunel university. | hutchinson-gilford progeria syndrome (hgps) is a severe premature ageing syndrome that affects children. these children display characteristics associated with normal ageing and die young usually from cardiovascular problems or stroke. classical hgps is caused by mutations in the gene encoding the nuclear structural protein lamin a. this mutation leads to a novel version of lamin a that retains a farnesyl group from its processing. this protein is called progerin and is toxic to cellular functio ... | 2011 | 22064469 |
| cholesterol. ii. diet and arterial diseases. | | 1963 | 14060412 |
| Contrasting effects of insect and molluscan herbivores on plant diversity in a long-term field experiment. | The importance of invertebrate herbivores in regulating plant communities remains unclear, due to the absence of long-term exclusion experiments. An experiment in an English grassland involving long-term exclusions of insect and mollusc herbivores, along with rabbit fencing, showed strong, but opposing, effects of the invertebrate herbivores. Plant species richness declined and biomass increased following insect exclusion, due to increased dominance by a grass species, whereas mollusc exclusion ... | 2011 | 22017580 |
| seroprevalence of serum bactericidal antibodies against group w135 and y meningococci in england in 2009. | serological surveillance has been used in the uk to inform vaccine policy for several infections, including group c meningococci. meningococcal conjugate vaccines, containing capsular groups a, w135 and y in addition to c are now available but their use in the uk is restricted to at risk groups and travellers to endemic areas. the aim of this study is to establish a baseline for natural immunity for groups w135 and y. serum samples collected in 2009 from individuals of all ages were obtained fro ... | 2011 | 22190393 |
| antibacterial prescribing patterns in small animal veterinary practice identified via savsnet: the small animal veterinary surveillance network. | in this study, data from veterinary clinical records were collected via the small animal veterinary surveillance network (savsnet). over a three-month period, data were obtained from 22,859 consultations at 16 small animal practices in england and wales: 69 per cent from dogs, 24 per cent from cats, 3 per cent from rabbits and 4 per cent from miscellaneous species. the proportion of consults where prescribing of antibacterials was identified was 35.1 per cent for dogs, 48.5 per cent for cats and ... | 2011 | 21911433 |
| a serological survey of encephalitozoon cuniculi infection in the wild rabbit in england and scotland. | sera from 175 wild rabbits trapped in england or scotland over the past two years were tested for antibodies to encephalitozoon cuniculi. no sera were positive, suggesting that this common laboratory rabbit pathogen is rare in wild rabbits in these areas. | 1980 | 7414097 |
| molecular species identification, host preference and detection of myxoma virus in the anopheles maculipennis complex (diptera: culicidae) in southern england, uk. | determining the host feeding patterns of mosquitoes by identifying the origin of their blood-meals is an important part of understanding the role of vector species in current and future disease transmission cycles. collecting large numbers of blood-fed mosquitoes from the field is difficult, therefore it is important to maximise the information obtained from each specimen. this study aimed to use mosquito genome sequence to identify the species within anopheles maculipennis sensu lato (an. macul ... | 2015 | 26271277 |
| personal reflections on 50 years of study of benzene toxicology. | the metabolism of benzene is reviewed, and the objectives of a quantitative balance study begun in 1945 are outlined; problems of toxicology and metabolism research of some 50 years ago are considered. the quantitative metabolism of 14c-benzene in the rabbit is annotated and compared with that of unlabeled benzene quantified by nonisotopic methods. the anomalies of phenylmercapturic acid and trans-trans-muconic acid as metabolites of benzene are examined in detail by isotopic and nonisotopic met ... | 1996 | 9118881 |
| molecular approaches for blood meal analysis and species identification of mosquitoes (insecta: diptera: culicidae) in rural locations in southern england, united kingdom. | thirty-four species of culicidae are present in the uk, of which 15 have been implicated as potential vectors of arthropod-borne viruses such as west nile virus. identification of mosquito feeding preferences is paramount to the understanding of vector-host-pathogen interactions which, in turn, would assist in the control of disease outbreaks. results are presented on the application of dna barcoding for vertebrate species identification in blood-fed female mosquitoes in rural locations. blood-f ... | 2017 | 28610033 |