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analysis of numbers of repeated units in r2 region among varicella-zoster virus strains.a variable region, r2, on the varicella-zoster virus (vzv) genome contains a repeated 42-bp unit.200312670723
experience with live attenuated varicella vaccine (oka strain) in healthy japanese subjects; 10-year survey at pediatric clinic.live attenuated varicella vaccine (oka strain, biken institute, osaka, japan) was administered to 973 healthy individuals over a 10-year period (1987-1997) at the pediatric clinic of showa hospital in japan. we evaluated the relevant serological and clinical data, which were collected by questionnaire. seroconversion by the immune adherence hemagglutination method was documented in 94% (805/860) of the initially seronegative subjects. of the initially seropositive subjects, 56% (63/113) showed e ...200010738094
varicella vaccine: the japanese experience.varicella vaccine developed by the biken institute (osaka, japan) was administered to 1.39 million subjects in japan and 1.93 million in korea between 1987 and 1993. six years after licensure, it was assessed for safety and efficacy under the regulatory requirements of the japanese government. clinical symptoms were reported in 6.9% (580/8429) of vaccines (mostly healthy children) and seroconversion in 91.5% (2347/2565), and the mean antibody titer 1 month after immunization was 12.2. despite 10 ...19968896537
increased incidence of herpes zoster in normal children infected with varicella zoster virus during infancy: community-based follow-up study.we surveyed outbreaks of varicella zoster virus (vzv) and herpes zoster virus, involving 31 outbreaks of chicken pox, in a semiclosed institution in osaka japan during the 34 years between 1949 and 1984. eight hundred forty-nine infants and children who had had clinical varicella during the first 4 years of life and those who had resided in the institution at least 12 to 144 months after the onset of varicella were included in the study. nine cases of zoster were observed among children who had ...19863005536
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