Publications

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malaria in brazil: what happens outside the amazonian endemic region.brazil, a country of continental proportions, presents three profiles of malaria transmission. the first and most important numerically, occurs inside the amazon. the amazon accounts for approximately 60% of the nation's territory and approximately 13% of the brazilian population. this region hosts 99.5% of the nation's malaria cases, which are predominantly caused by plasmodium vivax (i.e., 82% of cases in 2013). the second involves imported malaria, which corresponds to malaria cases acquired ...025185003
the genetic diversity of plasmodium malariae and plasmodium brasilianum from human, simian and mosquito hosts in brazil.plasmodium malariae is a protozoan parasite that causes malaria in humans and is genetically indistinguishable from plasmodium brasilianum, a parasite infecting new world monkeys in central and south america. p. malariae has a wide and patchy global distribution in tropical and subtropical regions, being found in south america, asia, and africa. however, little is known regarding the genetics of these parasites and the similarity between them could be because until now there are only a very few ...201222705349
natural plasmodium infection in monkeys in the state of rondônia (brazilian western amazon).simian malaria is still an open question concerning the species of plasmodium parasites and species of new world monkeys susceptible to the parasites. in addition, the lingering question as to whether these animals are reservoirs for human malaria might become important especially in a scenario of eradication of the disease. to aid in the answers to these questions, monkeys were surveyed for malaria parasite natural infection in the amazonian state of rondônia, brazil, a state with intense envir ...201323731624
malaria in brazil: an overview.malaria is still a major public health problem in brazil, with approximately 306,000 registered cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria occurred each year. as a result of the fight against the disease, the number of malaria cases decreased over the years and the smallest numbers of cases to-date were recorded in the 1960s. from the mid-1960s onwards, brazil underwent a rapid and disorganized settlement process in the amazon and this migrato ...201020433744
[molecular diagnosing of malaria in a tertiary care center in the brazilian amazon region].the routine test for diagnosing malaria is still the thick blood smear, despite its known decreased sensitivity and specificity in situations of low parasite density and mixed infections. the polymerase chain reaction is increasingly being used for molecular detection and identification of plasmodium species, due to its higher sensitivity and specificity. nested pcr was performed on whole-blood samples from 344 patients with acute febrile syndrome who came to a tertiary healthcare center in mana ...200818853011
prevalence and level of antibodies to the circumsporozoite protein of human malaria parasites in five states of the amazon region of brazil.the aim of this study was to determine the prevalence of malaria infection and antibodies against the repetitive epitopes of the circumsporozoite (cs) proteins of plasmodium falciparum, p. malariae, p. vivax vk210, p. vivax vk247, and p. vivax-like in individuals living in the states of rondônia, pará, mato grosso, amazonas, and acre. active malaria transmission was occurring in all studied sites, except in acre. p. falciparum was the predominant species in pará and rondônia and p. vivax in mato ...200717568943
malaria vectors in the municipality of serra do navio, state of amapá, amazon region, brazil.we conducted a survey to determine the vectors of malaria in six localities of serra do navio municipality, state of amapá, from 1990 to 1991. malaria infection rates of 29.3%, 6.2% and 20.4% were detected by human blood smears in colônia agua branca, porto terezinha and arrependido, respectively. there was no malaria infection detected in serra do navio. fifteen species were identified among 3,053 anopheline mosquitoes collected by human bait and 64.4% were identified as anopheles albitarsis s. ...200111285494
how prevalent is plasmodium malariae in rondônia, western brazilian amazon?we have compared results of plasmodium species identification obtained with conventional on-site microscopy of giemsa-stained thick smears (gts) and a semi-nested polymerase chain reaction (pcr) in 96 malaria patients from rondônia, western brazilian amazon. mixed-species infections were detected by pcr in 30% patients, but no such case had been found on gts. moreover, p. malariae infections were detected in 9 of 96 patients (10%) by pcr, but were not identified by local microscopists. the poten ...200011064586
[malaria in the municipality of humaitá, state of amazonas. xi - parasitological aspects]. 19817046016
malaria outside the amazon region: natural plasmodium infection in anophelines collected near an indigenous village in the vale do rio branco, itanhaém, sp, brazil.a few cases of plasmodium vivax malaria in which anophelines of subgenus kerteszia were incriminated as vectors have been reported outside the amazon region, in the atlantic forest. this study was carried out near an indigenous guarani village in the curucutu reserve, an environmental protection area in the municipality of itanhaém in the state of são paulo, brazil, on november 30, 2009, february 18, 2010, april 29, 2010 and may 26, 2010. mosquitoes were collected along the route to the guarani ...201322989665
identification of plasmodium spp. in neotropical primates of maranhense amazon in northeast brazil.in the brazilian amazon region, malaria caused by plasmodium malariae is considered to be a zoonosis because of cross-transfer of the parasite between humans and neotropical primates. to contribute information on this issue, we investigated occurrences of natural infection with plasmodium sp. among neotropical primates in the maranhense amazon (amazon region of the state of maranhão), in the northeastern region of brazil. blood samples were collected from 161 neotropical primates of six species ...201728796820
malaria in brazil, colombia, peru and venezuela: current challenges in malaria control and elimination.in spite of significant progress towards malaria control and elimination achieved in south america in the 2000s, this mosquito-transmitted tropical disease remains an important public health concern in the region. most malaria cases in south america come from amazon rain forest areas in northern countries, where more than half of malaria is caused by plasmodium vivax, while plasmodium falciparum malaria incidence has decreased in recent years. this review discusses current malaria data, policies ...201728676055
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