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assessment of alpha-fetoprotein in the diagnosis of hepatocellular carcinoma in middle eastern patients.alpha-fetoprotein (afp) levels for the diagnosis of hepatocellular carcinoma (hcc) may vary by geographical region and racial background. no data exists for this test in the middle eastern population. in addition, there is limited data on the impact of virological status on afp levels.201020397051
detection of hepatitis c virus and human immunodeficiency virus in expatriates in saudi arabia by antigen-antibody combination assays.the simultaneous detection of antigen and antibody was originally described for the early detection of the human immunodeficiency virus (hiv). the same approach was applied to detect the hepatitis c virus (hcv). the aim of this work was to use the antigen and antibody combination assay for the detection of hcv and hiv infections in expatriates in eastern saudi arabia.200919759481
incidence trends of viral hepatitis a, b, and c seropositivity over eight years of surveillance in saudi arabia.in saudi arabia, viral hepatitis ranked the second most common reportable viral disease in 2007, with almost 9000 new cases diagnosed in that year. the objective of this study was to determine the incidence trends of viral hepatitis seropositivity among the population served by the national guard health affairs (ngha) hospitals in the central, eastern, and western saudi arabia regions.201019540786
the prevalence of antibodies to hepatitis c virus in hail region, saudi arabia.the prevalence of subjects positive for anti-hcv antibodies was studied at hail region kingdom of saudi arabia (ksa). the study involved 8862 subjects tested for anti-hcv antibodies at king khalid general hospital during the years 1994-using elisa, a total prevalence of 5.09% positive subjects was found. the disease is shown to be mainly acquired at school age and adulthood. unlike hepatitis b virus, vertical transmission among preschool children does not seem to have an important role in transm ...199917216953
experience with endoscopy at bin jalawi hospital k.s.a.presentation of gastrointestinal disorders may vary in different communities. this study was carried out in town of hafoof in eastern zone of saudi arabia. purpose of the study was to observe pattern of presentation, age, sex, smoking status, haemoglobin levels, serological markers for hepatitis, endoscopic findings, histopathology, presence of h. pylori or otherwise in biopsy materials taken during the endoscopic procedures in patients undergoing endosopic examinations. findings of 230 endoscop ...200515929525
epidemiology of antibody to hepatitis b core antigen screening among blood donors in eastern saudi arabia. need to replace the test by hbv dna testing.prevention of the residual risk of transfusion transmitted hepatitis b virus (hbv) infection is mostly relied on serological screening of blood donors for antibody to hepatitis b core antigen (hbc), to detect donors in window period of hbv infection. this study was carried out to determine the prevalence of anti-hbc antibody among blood donors and its impact on rejection of collected blood units.200515770304
hepatitis b and hepatitis c virus prevalence among dialysis patients in bahrain and saudi arabia: a survey by serologic and molecular methods.hepatitis b virus (hbv) and hepatitis c virus (hcv) infections were assessed among 81 bahraini and 34 saudi hemodialysis patients and 7714 bahraini and 2330 saudi blood donors. higher prevalence of hcv (9.24% vs 0.30%), hepatitis b surface antigen (5.88% vs 0.62%) were seen in patients versus control patients, and in saudi patients compared with bahraini patients. hcv genotypes were hcv 1a/1b plus hcv 4 among bahraini patients and hcv 2/2a plus hcv 4 among saudi patients. this is the first repor ...200415573057
seroprevalence of hepatitis c virus and hepatitis b virus among dialysis patients in bahrain and saudi arabia.dialysis patients are at risk for contracting blood-borne infections, including hepatitis viruses (hbv and hcv). the aim of this study was to assess the prevalence of hbv and hcv infection among hamodialysis patients in bahrain and saudi arabia. study subjects comprised 81 bahraini and 34 saudi dialysis patients, and as control 7714 bahraini and 2330 saudi blood donors. serologic markers of hbv (hbsag, anti-hbc) and hcv (anti-hcv) were determined by eia and confirmed by pcr (hbv) and rt-pcr (hcv ...200415350487
prevalence of hepatitis c virus among bilharziasis patients.hepatitis c virus (hcv) infection with concurrent schistosoma mansoni infestation has emerged as a major cause of chronic liver disease and liver cirrhosis. the aim of this study was to investigate the prevalence of hcv among bilharzia patients.200414968219
the vulnerability of middle-aged and elderly patients to hepatitis c virus infection in a high-prevalence hospital-based hemodialysis setting.to determine the relationship between advancing age and the risk of acquiring hepatitis c virus (hcv) infection, through evaluation and statistical comparison of seroprevalence and seroconversion rates in different age groups of patients on long-term hemodialysis (hd).200414728634
hepatitis c genotypes/subtypes among chronic hepatitis patients in saudi arabia.the object of this study is to determine the molecular epidemiology of hepatitis c virus (hcv) in the kingdom of saudi arabia (ksa).200312897908
hepatis c virus genotype 4.hepatitis c virus genotype 4 chronic hepatitis predominates in the eastern mediterranean region of the world. in the kingdom of saudi arabia, as high as 62% of all cases are due to genotype 4. results of efficacy and safety clinical trials using pegylated-interferon plus ribavirin for chronic hepatitis c patients have shown great promise, but treatment of early responders should be maintained at 180 mg of pegylated-interferon alfa-2a plus 1000-1200 mg of ribavirin for 48 weeks unlike the 24 week ...200312897906
hepatitis c infection among egyptian blood donors in the eastern saudi arabia with / without past history of schistosomiasis.during 1991-1992, phlebotomists at blood bank facilities in eastern saudi arabia collected blood sera from 8934 adult male volunteer blood donors from saudi arabia and other countries (egyptians, other mid- easterners, southeast asians, and southern asians). laboratory personnel screened the sera for hepatitis c virus and the sera of egyptian donors for hepatitis b virus. they interviewed all the egyptian donors to determine their past history of exposure to and/or treatment for bilharziasis. ...199412287878
seroprevalence of hepatitis a virus markers in eastern saudi arabia.to record and update the sero-epidemiological status of hepatitis a virus in eastern saudi arabia. to investigate the main viral etiology of clinical hepatitis in children and discuss the possibility of introducing a hepatitis a virus vaccine in this province.200011369959
impact of dedicated space, dialysis equipment, and nursing staff on the transmission of hepatitis c virus in a hemodialysis unit of the middle east.infection with the hepatitis c virus (hcv) is endemic in hemodialysis (hd) units, especially in middle eastern countries. the meticulous isolation policy recommended for patients with the hepatitis b virus (hbv) in an hd unit resulted in a significant drop in hbv incidence globally. this study was developed to prospectively investigate the impact of an identical isolation policy on incidence of nosocomial hcv infection in this hd unit of the middle east.200312548254
tracing the epidemic history of hepatitis c virus genotypes in saudi arabia.hcv genotype 4 is highly prevalent in many middle eastern countries, yet little is known about the genotype's epidemic history at the subtype-level in this region. to address the dearth of data from saudi arabia (sa) we genotyped 230 hcv isolates in the core/e- and ns5b-region and analyzed using bayesian phylogenetic approaches. hcv genotype 4 (hcv/4) was positive in 61.7% (142/230) of isolates belonging to 7 different subtypes with the predominance of 4d (73/142; 51.4%) followed by 4a (51/142; ...201728458032
observations in a saudi-arabian dialysis population over a 13-year period.in contrast to europe and the usa, data concerning dialysis treatment in middle eastern countries like saudi arabia are lacking. we therefore studied 325 patients (150 females and 175 males) in one dialysis centre over a 13-year period. the number of primary renal diseases of uncertain aetiology and of pyelo/interstital nephritis caused by renal stone disease was high (46% and 4.9% resp.), that of diabetic nephropathy (14.8%) not much different from edta figures, while adult polycystic kidney di ...19947800203
pattern of blood procurement, ordering and utilization in a university hospital in eastern saudi arabia.the main objectives of this study were to review blood procurement, ordering, utilization, and causes of discarding blood in a university hospital and provide recommendations for improvement. the study was also aimed at sheding light on the frequency of seropositivity for certain disease markers in blood donors.200212070581
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