Publications

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familial aggregation of leishmania chagasi infection in northeastern brazil.a sample of 1,604 individuals belonging to 243 nuclear families from an endemic area of visceral leishmaniasis (jacobina, bahia state, brazil) was studied to disclose the intrafamilial pattern of infection. significant father to offspring, mother to offspring, and sibling to sibling associations, in contrast a with nonsignificant father to mother association, clearly indicate a familial aggregation of the infection, with a strong suggestion of at least partial genetic involvement.19957741179
a cross-sectional serodiagnostic survey of canine leishmaniasis due to leishmania chagasi.jequie, a community of about 144,500 inhabitants located in the state of bahia, brazil, is endemic for both visceral and cutaneous leishmaniases. in the present epidemiologic study, the urban and inhabited periurban areas of the town were divided into 140 clusters of 0.25 km2 each. the seroprevalence of canine leishmania antibodies was investigated using an enzyme-linked immunosorbent assay as a screening test since its sensitivity was significantly higher than that of an indirect immunofluoresc ...19968702020
ecological interactions of visceral leishmaniasis in the state of bahia, brazil.the laboratory and field observations summarized in this paper on visceral leishmaniasis ecology in the state of bahia, brazil are based on the author's observations over the past 35 years in a number of state's foci, public health records and literature citations. the disease is endemic with epidemic outbreaks occurring every ten years and its geographical distribution is expanding rapidly in the last years. leishmania chagasi is the main ethiologic agent of the visceral leishmaniasis but le. a ...19969283643
studies on control of visceral leishmaniasis: impact of dog control on canine and human visceral leishmaniasis in jacobina, bahia, brazil.to assess the effect of removing leishmania-infected dogs on the incidence of visceral leishmaniasis, a controlled intervention study was performed in northeast brazil. the attempted elimination of seropositive dogs resulted in an initial significant decrease in the annual incidence of seroconversion among dogs from 36% to 6% over the first two years. in the following two years, the incidence increased to 11% and 14%, respectively. in a control area in which dogs were surveyed but seropositive d ...19989684628
ecological niche modeling for visceral leishmaniasis in the state of bahia, brazil, using genetic algorithm for rule-set prediction and growing degree day-water budget analysis.two predictive models were developed within a geographic information system using genetic algorithm rule-set prediction (garp) and the growing degree day (gdd)-water budget (wb) concept to predict the distribution and potential risk of visceral leishmaniasis (vl) in the state of bahia, brazil. the objective was to define the environmental suitability of the disease as well as to obtain a deeper understanding of the eco-epidemiology of vl by associating environmental and climatic variables with d ...200618686237
leishmania (viannia) braziliensis in dogs in brazil: epidemiology, co-infection, and clinical aspects.leishmaniasis is an endemic disease present in 98 countries. in brazil, the northeast region accounts for approximately half of the cases in humans, and has experienced an increased number of positive cases in dogs. in this study, we investigated the epidemiology of canine leishmaniasis in the city of ilhéus, bahia, using serological and molecular techniques and evaluated the possible environmental risk factors and associated clinical signs. blood samples were collected from 560 dogs in urban an ...201526505353
serological survey of leishmania infection in blood donors in salvador, northeastern brazil.visceral leishmaniasis is endemic to brazil, where it is caused by leishmania infantum (syn. leishmania chagasi). following parasite inoculation, individuals may experience asymptomatic infection, raising the possibility of parasite transmission through the transfusion of contaminated blood products. in the present work, we evaluated the prevalence of asymptomatic leishmania infection among blood donors in salvador, northeastern brazil.201425073468
genetic variability of leishmania infantum in naturally infected dogs in the state of bahia, brazil.in brazil, leishmania infantum mainly affects humans and dogs. the state of bahia presents many dogs that are positive for this parasite. despite the importance of epidemiology in this region, there are still very few studies that have assessed the genetic characteristics of l. infantum. the aim of this study is to investigate the genetic variability of l. infantum isolated identified in naturally infected dogs, in order to verify occurrence of subpopulation of this parasite in the different bio ...201728700001
sandflies (diptera: psychodidae) in an urban area of northeastern brazil.the sandfly fauna is well studied globally. in brazil, sandfly fauna is very diverse in the northeast region, especially in states such as maranhão, ceará, and bahia. however, in the state of pernambuco, the distribution of these insects is still not well known. therefore, the objective of this study was to identify the different species that constitute the sandfly fauna in an urban area in the northeast region of brazil, where an outbreak of visceral leishmaniasis (vl) was recently reported.201728001216
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