| leishmania-human immunodeficiency virus coinfection in the mediterranean basin: isoenzymatic characterization of 100 isolates of the leishmania infantum complex. | isoenzymatic characterization was done on 100 isolates obtained from visceral leishmaniasis (vl) patients coinfected with human immunodeficiency virus (hiv); isolates had been received between 1986 and 1993 at the international leishmania cryobank and identification centre in montpellier, france. electrophoresis was done with 15 isoenzymes using the starch gel technique combined, where appropriate, with isoelectrofocusing. nine leishmania infantum zymodemes were identified; l. infantum zymodeme ... | 1995 | 7797943 |
| isoenzymatic analysis of 712 strains of leishmania infantum in the south of france and relationship of enzymatic polymorphism to clinical and epidemiological features. | in the south of france, leishmaniasis due to leishmania infantum occurs in the following five foci of endemicity (from west to east): pyrénées-orientales, cévennes, provence, côte d'azur, and corsica. between 1981 and 2002, 712 leishmania strains obtained from humans, dogs, cats, and sand flies were studied by isoenzyme analysis. in total, seven zymodemes were identified: mon-1, mon-11, mon-24, mon-29, mon-33, mon-34, and mon-108. the pyrénées-orientales focus is characterized by a predominance ... | 2004 | 15364993 |
| [leishmania infantum nicolle, 1908, the agent of the autochthonous oriental sore. apropos of the biochemical identification of 2 strains isolated in the eastern pyrenees]. | two strains of parasites isolated from cases of oriental sore in the pyrénées-orientales were identified by electrophoretic analysis of eight isoenzymes (pgm, pgi, g-6-pdh, 6-pgdh, idh, mdh, me and got). both strains were identical with leishmania infantum nicolle, 1908, which normally causes visceral leishmaniasis. it is probable that, in the mediterranean region, some cutaneous lesions observed within the area of visceral leishmaniasis are caused by this species rather than by leishmania tropi ... | 1980 | 6780226 |
| enzymatic polymorphism during leishmania/hiv co-infection: a study of 381 leishmania strains received between 1986 and 2000 at the international cryobank in montpellier, france. | between 1986 and 2000, 381 leishmania strains isolated from 288 hiv-positive patients were studied at the international cryobank in montpellier, france. most (95.1%) of the strains came from cases of visceral leishmaniasis but 4.9% were from hiv-positives with cutaneous leishmaniasis. the majority of the strains came from patients infected in the mediterranean region, with a few originating in sub-saharan africa and south america. isoenzymatic characterization revealed 28 zymodemes in four diffe ... | 2003 | 14678632 |
| genomic polymorphism of leishmania infantum: a relationship with clinical pleomorphism? | leishmania infantum is the etiological agent of visceral (vl) and a cutaneous form (cl) of leishmaniasis around the mediterranean basin. in order to document the parasite genetic background corresponding to this clinical diversity, chromosome size polymorphism was analysed in 32 french isolates (18 cl and 14 vl) originating from the cévennes and the pyrénées orientales (po), and corresponding to zymodemes mon-1 and mon-29. five chromosomes bearing tandemly repeated genes encoding for important a ... | 2001 | 12798050 |