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susceptibility of haemophilus influenzae to antimicrobial agents used in canada. canadian study group.we evaluated the incidence of haemophilus influenzae resistance to selected antimicrobials used in canada. from 1985 to 1987, 2503 h. influenzae isolates obtained in 14 hospitals across canada were sent to the centre hospitalier de l'université laval (chul) for identification, serotyping, biotyping and testing for beta-lactamase production. susceptibility tests were done with the use of 12 antibiotics. of the strains 424 (16.9%) produced beta-lactamase; the proportion varied from 12.8%, in newfo ...19902224717
mycobacterium xenopi infection in patients with human immunodeficiency virus infection.mycobacterium xenopi is one of the most frequently isolated nontuberculous mycobacteria in ontario, canada. we reviewed the records of 28 human immunodeficiency virus (hiv)-infected patients from whom m. xenopi was isolated between 1982 and 1995. m. xenopi was recovered from respiratory specimens from 24 patients, most of whom had clinical and radiographic evidence of pulmonary disease. however, coexistent pulmonary infection due to other pathogens was found in 17 patients: pneumocystis carinii ...19979332511
the pediatric economic database evaluation (pede) project: establishing a database to study trends in pediatric economic evaluation.while standard methods for conducting economic evaluations have evolved, little attention has been paid to the conduct of these studies in special populations such as children.200314515110
volume matters: physician practice characteristics and immunization coverage among young children insured through a universal health plan.we studied the association between immunization coverage for a cohort of 2-year-old children covered by a universal health insurance plan and pediatric provider and other health services characteristics.200616510636
invasive haemophilus influenzae serotype b surveillance in ontario--documenting the progression towards elimination. 199910624034
adult epiglottitis: the toronto hospital experience.this study was conducted to gain insight into the diagnosis, treatment, and outcome measures in adult patients presenting with acute epiglottitis.19989857318
antibiotic susceptibility of blood and cerebrospinal fluid isolates of haemophilus influenzae.one hundred and sixty-nine blood and cerebrospinal fluid isolates of haemophilus influenzae, collected in the province of ontario from children and adults from 1976 to 1983, were tested for susceptibility to six conventional and eight newer antibacterial drugs. most active were ceftriaxone, ceftizoxime and cefotaxime (mic90 less than or equal to 0.02 mg/l); latamoxef (moxalactam), acrosoxacin and ceftazidime were close behind with mic90s in the 0.05-0.09 mg/l range. twenty-five strains (14.8%) w ...19853872296
hib vaccine coverage in children attending day care/nursery school in east york.this survey assessed haemophilus influenzae b vaccine coverage and factors affecting compliance in children at increased risk. a telephone survey was conducted of a random sample of 75 children, aged 24-60 months, attending licensed day care/nursery schools in east york. 96% of the sample was surveyed; only 51% were vaccinated. older children were less likely to be immunized and there were more single-parent families among the non-vaccinated. the age, educational level and country of birth of th ...19902331655
neglected infectious diseases in aboriginal communities: haemophilus influenzae serotype a and helicobacter pylori.this report describes proceedings of a workshop entitled "neglected infectious diseases in aboriginal communities" which took place in thunder bay, ontario, canada, on october 12, 2011. this workshop was jointly organized by the national research council of canada (nrc), the national microbiology laboratory (public health agency of canada) and northern ontario school of medicine (nosm) with participants from the medical sciences division and clinical sciences division of nosm, nrc, national micr ...201223046541
validation of infant immunization billing codes in administrative data.ontario has a single payer provincial health insurance program. administrative data may provide a potentially robust source of information for post-marketing vaccine studies. vaccine-specific immunization billing codes were introduced in 2011. our objective was to validate ontario's universal health care administrative datasets to assess infant immunization status. electronic medical record data from the electronic medical record administrative data linked database (emrald) was used as the refer ...201526075651
the epidemiology of invasive haemophilus influenzae non-serotype b disease in ontario, canada from 2004 to 2013.since the widespread use of haemophilus influenzae (hi) type b (hib) vaccines among children aged <5 years, an increase in invasive non-hib disease incidence has been reported internationally. we sought to describe the epidemiology of invasive non-hib disease in ontario, canada (population ~13.5 million).201526569613
invasive disease caused by haemophilus influenzae type a in northern ontario first nations communities.seven epidemiologically unrelated cases of invasive haemophilus influenzae type a (hia) disease were identified in first nations communities of northwestern ontario, canada, in 2004-2008. in all cases, hia was isolated from blood. the clinical presentation in most of the cases was moderately severe and all patients responded to antibiotic therapy. laboratory analysis of hia isolates from northwestern ontario indicated striking similarities in their phenotypic and genotypic characteristics. the f ...201021148281
changing epidemiology of invasive haemophilus influenzae in ontario, canada: evidence for herd effects and strain replacement due to hib vaccination.the epidemiology of invasive haemophilus influenzae infections was evaluated in ontario between 1989 and 2007 to assess the impact of the introduction of the conjugate h. influenzae serotype b (hib) vaccine in the early 1990 s on hib and non-hib serotypes in both vaccinated and unvaccinated cohorts as well as the possibility of "strain replacement" with non-vaccine h. influenzae strains. data were collected by the provincial public health laboratories-toronto, ontario agency for health protectio ...201020398617
invasive haemophilus influenzae disease caused by non-type b strains in northwestern ontario, canada, 2002-2008.a high incidence of invasive non-type b haemophilus influenzae disease was found in northwestern ontario, canada; h. influenzae type a was the most prevalent serotype (42%). clinical and demographic analyses indicate that aboriginal children aged <5 years and adults with predisposing medical conditions are the most affected by invasive h. influenzae disease in the post-h. influenzae vaccine era.200919761408
seasonal variation in rates of emergency room visits and acute admissions following recommended infant vaccinations in ontario, canada: a self-controlled case series analysis.to determine if birth month has an effect on the incidence of adverse events following the 2- and 12-month recommended vaccinations.201425446834
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