Publications

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the effect on fetal growth of protozoan and helminthic infection during pregnancy.this is a prospective study of 14,914 pregnant women conducted in guatemala city, guatemala. stool samples were obtained from the studied patients before the first prenatal visit (mean gestational age 21.6 +/- 8.4 weeks) for the diagnosis of parasitic infections during pregnancy. forty-four percent had at least one parasite detected, and 24% were infected with helminths. ascaris lumbricoides was the most prevalent (14.5%). infected mothers were less educated, had less adequate water and sanitary ...19892586958
the distribution of intestinal helminth infections in a rural village in guatemala.fecal egg count scores were used to investigate the distribution and abundance of intestinal helminths in the population of a rural village. prevalences of the major helminths were 41% with ascaris lumbricoides, 60% with trichuris trichiura and 50% with necator americanus. all three parasites showed a highly aggregated distribution among hosts. age/prevalence and age/intensity profiles were typical for both a. lumbricoides and t. trichiura with the highest worm burdens in the 5-10 year old child ...19938246757
the effects of deworming on indicators of school performance in guatemala.intestinal helminths are among the most common infections in school-age children. of 246 children, aged 7-12 years, attending school in rural guatemala, 91% carried ascaris lumbricoides and 82% carried trichuris trichiura. these children were randomly assigned to receive either albendazole or placebo at 0 and 12 weeks in a 'double-blind' study of the effects of deworming on indicators of school performance. albendazole successfully rid the children of ascaris but it was less effective against tr ...19968761577
nutritional status indicators and their interactions in rural guatemalan elderly: a study in san pedro ayampuc.anthropometry and body-composition measures, hematologic and biochemical measures of nutritional status, and helminthic infection were studied in the population of elderly persons (> or = 60 y of age) in a rural village in guatemala that was 65% mayan (indigenous) and 35% ladino (european). the population had low levels of literacy and formal education. the elderly persons were much shorter and lighter than reference populations. anemia was present in 18% of the population, and riboflavin and vi ...19979322552
the aba-1 allergen of ascaris lumbricoides: sequence polymorphism, stage and tissue-specific expression, lipid binding function, and protein biophysical properties.the aba-1 protein of ascaris lumbricoides (of humans) and ascaris suum (of pigs) is abundant in the pseudocoelomic fluid of the parasites and also appears to be released by the tissue-parasitic larvae and the adult stages. the genes encoding the polyprotein precursor of aba-1 (aba-1) were found to be arranged similarly in the two taxa, comprising tandemly repeating units encoding a large polyprotein which is cleaved to yield polypeptides of approximately 15 kda which fall into 2 distinct classes ...200010726282
day-to-day variations in iron, zinc and copper in breast milk of guatemalan mothers.to assess the within-subject and between-subject coefficients of variation (cv) of iron, zinc and copper concentrations in the milk of guatemalan mothers.200515699684
effect of tourism and trade on intestinal parasitic infections in guatemala.a survey was performed to determine if infection with gastrointestinal parasites differs between the rural and urban poor inhabitants of guatemala. a total of 317 stool samples from children in two towns, one rural and one urban, were examined using the formalin-ether concentration method. the overall prevalence of parasites in infected children was 67%, 20%, 30%, and 22%, respectively for ascaris lumbricoides, trichuris trichiura, giardia duodenalis and entamoeba histolytica in the rural town o ...200918941875
a retrospective analysis of prevalence of gastrointestinal parasites among school children in the palajunoj valley of guatemala.this study retrospectively analyzed demographic factors that may affect the prevalence of intestinal parasites among guatemalan school children. the findings of the study showed that young age, wet season, female gender, and severe malnutrition all correlated positively with increased rates of infection. clinical visits were performed on 10,586 school children aged 5-15 years over a four-year period (2004-2007) in the palajunoj valley of guatemala, during which 5,705 viable stool samples were sc ...200919248646
prevalence of multi-gastrointestinal infections with helminth, protozoan and campylobacter spp. in guatemalan children.the prevalence of multi-infections with helminthes, protozoans and campylobacter spp. in guatemalan children is a reflection of differences in the risk factors related to pathogen transmission.200919759480
molecular insights for giardia, cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system in guatemala.abstract. we molecularly characterized samples with giardia, cryptosporidium, and soil-transmitted helminths from a facility-based surveillance system for diarrhea in santa rosa, guatemala. the dna sequence analysis determined the presence of giardia assemblages a (n = 7) and b (n = 12) and, cryptosporidium hominis (n = 2) and cryptosporidium parvum (n = 2), suggestive of different transmission cycles. all 41 samples with soil-transmitted helminths did not have the β-tubulin mutation described f ...201122144459
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