Publications

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persistence of humoral response against sporozoite and blood-stage malaria antigens 7 years after a brief exposure to plasmodium vivax.the persistence of malarial antibodies was evaluated in subjects living in a rural community (in minas gerais state, brazil) briefly exposed to a plasmodium vivax malaria outbreak outside of the area in which malaria was endemic. transmission was interrupted by treatment of all patients and their relatives and/or neighbors, although the latter had neither symptoms nor blood parasites. antibodies to p. vivax antigens (recombinant proteins from sporozoites [rpvcs] and from blood stages [rpv200]) w ...19989535000
the duffy binding protein as a key target for a plasmodium vivax vaccine: lessons from the brazilian amazon.plasmodium vivax infects human erythrocytes through a major pathway that requires interaction between an apical parasite protein, the duffy binding protein (pvdbp) and its receptor on reticulocytes, the duffy antigen/receptor for chemokines (darc). the importance of the interaction between pvdbp (region ii, dbpii) and darc to p. vivax infection has motivated our malaria research group at oswaldo cruz foundation (state of minas gerais, brazil) to conduct a number of immunoepidemiological studies ...201425185002
plasmodium vivax sporozoite antibodies in individuals exposed during a single malaria outbreak in a non-endemic area.we studied seroreactivity against plasmodium vivax antigens in 62 individuals living in a small community near mantena, minas gerais, brazil, an area outside the endemic malaria zone brazil. eight months earlier, there had been transmission of p. vivax for a period of 50 days, which was then totally controlled by chemotherapy and insecticides. an anti-sporozoite response, measured by elisa using a recombinant protein expressed in yeast, was detected in 45% (14 of 31) of individuals eight months ...19911996737
malaria outbreaks in a non-endemic area of brazil, 2005.in march 2005, a resident of the municipality of monte alegre de minas, state of minas gerais, without any history of traveling to endemic areas for malaria, was diagnosed with plasmodium vivax infection and local mosquito-borne transmission was suspected. the epidemiological investigation identified another 10 cases with local transmission and all of them were related to the imported malaria case that was detected in this region. the potential exposure site was the banks of the river tejuco, an ...200818719800
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