Publications

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a trial of ci-564 (dapolar), a repository antimalarial for prophylaxis in amapá, brazil. 19704911012
distribution of plasmodium vivax variants (vk210, vk247 and p. vivax-like) in three endemic areas of the amazon region of brazil and their correlation with chloroquine treatment.the present study evaluated the glass fibre membrane (gfm)-polymerase chain reaction (pcr)-enzyme-linked immunosorbent assay (elisa) technique for genotyping the plasmodium vivax variants, to verify the distribution of p. vivax variants (vk210, vk247 and p. vivax-like) in parts of brazil and their correlation with levels of parasitaemia, previous malaria experience and clearance of parasitaemia linked to different treatment schedules. the samples were taken from individuals living in macapá, por ...200011127238
concurrent dengue and malaria in the amazon region.the amazon region has extensive forested areas and natural ecosystems, providing favorable conditions for the existence of innumerous arboviruses. over 200 arboviruses have been isolated in brazil and about 40 are associated with human disease. four out of 40 are considered to be of public health importance in brazil: dengue viruses (1-4), oropouche, mayaro and yellow fever. along with these viruses, about 98% of the malaria cases are restricted to the legal amazon region.201021085859
habitat suitability of anopheles vector species and association with human malaria in the atlantic forest in south-eastern brazil.every year, autochthonous cases of plasmodium vivax malaria occur in low-endemicity areas of vale do ribeira in the south-eastern part of the atlantic forest, state of são paulo, where anopheles cruzii and anopheles bellator are considered the primary vectors. however, other species in the subgenus nyssorhynchus of anopheles (e.g., anopheles marajoara) are abundant and may participate in the dynamics of malarial transmission in that region. the objectives of the present study were to assess the ...201121881779
evaluation of the naturally acquired antibody immune response to the pv200l n-terminal fragment of plasmodium vivax merozoite surface protein-1 in four areas of the amazon region of brazil.frequency and levels of igg antibodies to an n-terminal fragment of the plasmodium vivax msp-1 (pv200l) protein, in individuals naturally exposed to malaria in four endemic areas of brazil, were evaluated by enzyme-linked immunosorbent assay. plasma samples of 261 p. vivax-infected individuals from communities of macapá, novo repartimento, porto velho, and plácido de castro in the amazonian region with different malaria transmission intensities. a high mean number of studied individuals (89.3%) ...201121292879
molecular screening of plasmodium sp. asymptomatic carriers among transfusion centers from brazilian amazon region.the transmission of malaria in brazil is heterogeneous throughout endemic areas and the presence of asymptomatic plasmodium sp. carriers (apcs) in the brazilian amazon has already been demonstrated. malaria screening in blood banks is based on the selection of donors in respect to possible risks associated with travel or residence, clinical evidence and/or inaccurate diagnostic methods thereby increasing the probability of transfusion-transmitted infection. we evaluated the frequency of apcs in ...200717384812
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