| efficacy of dihydroartemisinin-piperaquine for treatment of uncomplicated plasmodium falciparum and plasmodium vivax in cambodia, 2008 to 2010. | we describe here the results of antimalarial therapeutic efficacy studies conducted in cambodia from 2008 to 2010. a total of 15 studies in four sentinel sites were conducted using dihydroartemisinin-piperaquine (dp) for the treatment of plasmodium falciparum infection and chloroquine (cq) and dp for the treatment of p. vivax infection. all studies were performed according to the standard world health organization protocol for the assessment of antimalarial treatment efficacy. among the studies ... | 2013 | 23208711 |
| passive case detection of malaria in ratanakiri province (cambodia) to detect villages at higher risk for malaria. | cambodia reduced malaria incidence by more than 75% between 2000 and 2015, a target of the millennium development goal 6. the cambodian government aims to eliminate all forms of malaria by 2025. the country's malaria incidence is highly variable at provincial level, but less is known at village level. this study used passive case detection (pcd) data at village level in ratanakiri province from 2010 to 2014 to describe incidence trends and identify high-risk areas of malaria to be primarily targ ... | 2017 | 28264678 |
| geographical patterns of malaria transmission based on serological markers for falciparum and vivax malaria in ratanakiri, cambodia. | malaria transmission is highly heterogeneous, especially in low endemic countries, such as cambodia. this results in geographical clusters of residual transmission in the dry, low transmission season, which can fuel the transmission to wider areas or populations during the wet season. a better understanding of spatial clustering of malaria can lead to a more efficient, targeted strategy to reduce malaria transmission. this study aims to evaluate the potential of the use of serological markers to ... | 2016 | 27756395 |
| sub-microscopic malaria cases and mixed malaria infection in a remote area of high malaria endemicity in rattanakiri province, cambodia: implication for malaria elimination. | malaria microscopy and rapid diagnostic tests are insensitive for very low-density parasitaemia. this insensitivity may lead to missed asymptomatic sub-microscopic parasitaemia, a potential reservoir for infection. similarly, mixed infections and interactions between plasmodium species may be missed. the objectives were first to develop a rapid and sensitive pcr-based diagnostic method to detect low parasitaemia and mixed infections, and then to investigate the epidemiological importance of sub- ... | 2010 | 20409349 |