| genetic structure of plasmodium vivax isolates from two malaria endemic areas in afghanistan. | in this study, the nature and extent of genetic diversity of plasmodium vivax populations circulating in afghanistan have been investigated by analyzing three genetic markers: csp, msp-1, and msp-3 alpha. blood samples (n=202) were collected from patients presenting with vivax malaria from south-western (herat) and south-eastern (nangarhar) parts of afghanistan, and analysed using nested-pcr/rflp and sequencing methods. genotyping pvmsp-1 revealed type 1, type 2 and recombinant type 3 allelic va ... | 2010 | 19716798 |
| molecular surveillance of plasmodium vivax dhfr and dhps mutations in isolates from afghanistan. | analysis of dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutations in plasmodium vivax wild isolates has been considered to be a valuable molecular approach for mapping resistance to sulphadoxine-pyrimethamine (sp). the present study investigates the frequency of snps-haplotypes in the dhfr and dhps genes in p. vivax clinical isolates circulating in two malaria endemic areas in afghanistan. | 2010 | 20226087 |
| field trial of three different plasmodium vivax-detecting rapid diagnostic tests with and without evaporative cool box storage in afghanistan. | accurate parasitological diagnosis of malaria is essential for targeting treatment where more than one species coexist. in this study, three rapid diagnostic tests (rdts) (accessbio carestart (cspfpan), carestart pfpv (cspfpv) and standard diagnostics bioline (sdbpfpv)) were evaluated for their ability to detect natural plasmodium vivax infections in a basic clinic setting. the potential for locally made evaporative cooling boxes (ecb) to protect the tests from heat damage in high summer tempera ... | 2011 | 21696587 |