association of human leukocyte antigen dq1 and dengue fever in a white southern brazilian population. | dengue is an infectious disease of viral etiology transmitted by the mosquitoes aedes aegypti, a. albopictus, and a. scutellaris. it can develop either as a benign form or as a severe hemorrhagic form. previous work showed an association of the hemorrhagic form with human leukocyte antigens (hla), suggesting a role of genetic factors in disease susceptibility. nevertheless, data on hla association with the classical form of the disease is scarce in literature. sixty-four patients and 667 normal ... | 2004 | 15558162 |
dengue virus type 4 phylogenetics in brazil 2011: looking beyond the veil. | dengue fever and dengue hemorrhagic fever are diseases affecting approximately 100 million people/year and are a major concern in developing countries. in the present study, the phylogenetic relationship of six strains of the first autochthonous cases of denv-4 infection occurred in sao paulo state, parana state and rio grande do sul state, brazil, 2011 were studied. nucleotide sequences of the envelope gene were determined and compared with sequences representative of the genotypes i, ii, iii a ... | 2011 | 22216365 |