Publications

TitleAbstractYear
Filter
PMID
Filter
dengue haemorrhagic fever in malaysia: a review.the historical background, epidemiology and changing pattern of clinical disease as seen in malaysia is reviewed. the preliminary results of the longitudinal study of epidemiology of dengue in malaysia is also presented. studies led by rudnick et al. over some 18 years have established that the disease is endemically transmitted by both aedes aegypti and aedes albopictus causing illnesses ranging from mild febrile episodes through classical dengue fever, dengue haemorrhagic fever and the dengue ...19873324361
rainfall, abundance of aedes aegypti and dengue infection in selangor, malaysia.an epidemio-meteorotropic analytical study of selangor, in the southwest coast of peninsular malaysia, examines the monthly incidence of dengue for the period 1973-1982 to assess possible quantitative association with the monthly rainfall. the relationships between rainfall, abundance of a. aegypti and dengue infection during 1982 in jinjang, a dengue-prone area in selangor, were also examined. a quantitative association between rainfall and the number of dengue cases was found during the first ...19853835698
dengue vector surveillance in urban residential and settlement areas in selangor, malaysia.ovitrap surveillance was conducted in two urban residential areas (taman samudera timur and taman samudera selatan) and in a settlement area (kampung banjar), which is located 16 km from kuala lumpur city center, malaysia. in taman samudera, dengue cases were reported monthly in 2003/2004. thus, a study was initiated to determine the distribution and abundance of dengue vectors, aedes aegypti and ae. albopictus. the ovitrap surveillance indicated that ae. aegypti and ae. albopictus were present ...200516880752
chikungunya virus infection.chikungunya virus (chikv) is a mosquito-borne alphavirus which causes epidemic fever, rash and polyarthralgia in africa and asia. two outbreaks have been reported in malaysia, in klang, selangor (1998) and bagan panchor, perak (2006). it is not known if the outbreaks were caused by the recent introduction of chikv, or if the virus was already circulating in malaysia. seroprevalence studies from the 1960s suggested previous disease activity in certain parts of the country. in asia, chikv is thoug ...200616898330
isolation of monoclonal antibodies-escape variant of dengue virus serotype 1.during an outbreak from december 2004 to march 2005, 138 isolates of dengue virus were prospectively obtained from acute-phase serum samples of 1,067 patients with the provisional clinical diagnosis of acute dengue illness admitted to the adult wards of hospital tengku ampuan rahimah, klang, malaysia. of the 138 dengue virus isolates, 87, 11, 24 and 3 were typed as dengue serotypes 1, 2, 3 and 4, respectively, by a commercial dengue virus typing kit using monoclonal antibodies (mab). 13 dengue v ...200617075660
an epidemiological cluster pattern of dengue outbreak amongst close contacts in selangor, peninsular malaysia.dengue fever is major public health problem especially among the highly urbanized states of malaysia, such as, selangor and kuala lumpur federal territory. we report an epidemiological cluster pattern of dengue outbreak in the district of gombak, selangor that may mimic other acute febrile illnesses in which the transmission mode is via close contact. this dengue outbreak consisted of two waves; an initial cluster of three cases (including the first deceased, ji) which occurred between 20th and ...200617240578
mixed breeding of aedes aegypti (l.) and aedes albopictus skuse in four dengue endemic areas in kuala lumpur and selangor, malaysia.ovitrap surveillance was conducted in four dengue endemic areas in kuala lumpur and selangor, malaysia to determine the distribution and percentage of mixed breeding of both aedes aegypti and aedes albopictus. the percentage of mixed breeding in all study sites both indoors and outdoors accounted for 10 to 32 % from the total ovitraps collected. ae. aegypti was found at a higher frequency than ae. albopictus in these ovitraps. this study again indicates that ovitrap is a sensitive tool to attrac ...200617322826
impact of larviciding with a bacillus thuringiensis israelensis formulation, vectobac wg, on dengue mosquito vectors in a dengue endemic site in selangor state, malaysia.the field bioefficacy of a wettable granule (wg) formulation of bacillus thuringiensis israelensis (bti), vectobac wg (bti strain am65-52) against dengue vectors, aedes aegypti and ae albopictus; was evaluated in a suburban residential area (tst) and in a temporary settlement site (kb) in the state of selangor, malaysia. pre-control ovitrap surveillance of the trial sites indicated a high population of both types of aedes mosquitoes. the populations were monitored continuously by weekly ovitrapp ...200819058596
susceptibility of field-collected aedes aegypti (l.) (diptera: culicidae) to bacillus thuringiensis israelensis and temephos.the susceptibility status of field-collected aedes aegypti (l.) from a dengue endemic area to bacillus thuringiensis israelensis (bti) and temephos was determined. since august 2007, biweekly ovitrap surveillance (os) was conducted for 12 mo in 2 sites, a & b, in shah alam, selangor. site a was treated with a bti formulation, vectobac® wg at 500 g/ha, from december 2007 - june 2008 while site b was subjected to routine dengue vector control activities conducted by the local municipality. aedes a ...201021399591
assessing weather effects on dengue disease in malaysia.the number of dengue cases has been increasing on a global level in recent years, and particularly so in malaysia, yet little is known about the effects of weather for identifying the short-term risk of dengue for the population. the aim of this paper is to estimate the weather effects on dengue disease accounting for non-linear temporal effects in selangor, kuala lumpur and putrajaya, malaysia, from 2008 to 2010. we selected the weather parameters with a poisson generalized additive model, and ...201324287855
vertical distribution of aedes mosquitoes in multiple storey buildings in selangor and kuala lumpur, malaysia.the aim of the present study was to determine the vertical distribution and abundance of aedes mosquitoes in multiple storey buildings in selangor and kuala lumpur, malaysia. ovitrap surveillance was conducted for 4 continuous weeks in multiple storey buildings in 4 residential areas located in selangor [kg. baiduri (kb)] and kuala lumpur [student hostel of university of malaya (um), kg. kerinchi (kk) and hang tuah (ht)]. the results implied that aedes mosquitoes could be found from ground floor ...201323665706
surveillance of adult aedes mosquitoes in selangor, malaysia.to determine the effectiveness of using sticky traps and the ns1 dengue antigen kit for the surveillance of aedes mosquitoes for dengue control.201526094839
surveillance of aedes albopictus skuse breeding preference in selected dengue outbreak localities, peninsular malaysia.entomological surveillance was conducted in order to determine the abundance and to evaluate any changes of biological vectors or ecology, especially in the dengue outbreak areas. the abundance and breeding preference of aedes albopictus and aedes aegypti were conducted in selected dengue outbreak localities in three states of peninsular malaysia namely selangor, federal territory of kuala lumpur, and penang island using ovitraps and larval survey method. it was determined that ae. albopictus wa ...201525801254
relationship between rainfall and aedes larval population at two insular sites in pulau ketam, selangor, malaysia.two insular settlements (kampung pulau ketam and kampung sungai lima) were selected to study the population dynamics of aedes aegypti and aedes albopictus mosquitoes, vectors of dengue and chikungunya infections. ovitrap surveillance was conducted between october 2007 and october 2008. there was an inverse negative association between ovitrap index and rainfall at the time of collection, probably because rainfall increased the number of available oviposition sites. rainfall and ovitrap index wer ...201323691624
insecticide susceptibility status of field-collected aedes (stegomyia) aegypti (l.) at a dengue endemic site in shah alam, selangor, malaysia.biweekly ovitrap surveillance (os) was conducted for a year (august 2007 - september 2008) at two different dengue endemic sites in shah alam, selangor, malaysia, 50 km from kuala lumpur. aedes aegypti collected from these 2 locations were raised to the f3 stage and subjected to a who standard bioassay method to determine lethal time (lt) against pyrethroids (permethrin 0.75%, cyfluthrin 0.15%), organophosphates (malathion 5.0%, fenitrothion 1.0%), carbamates (propoxur 0.1%, bendiocarb 0.1%) and ...201223082552
dengue vector surveillance in insular settlements of pulau ketam, selangor, malaysia.a year-long ovitrap surveillance was conducted between november 2007 and october 2008 in two insular settlements (kampung pulau ketam and kampung sungai lima) within the malaysian island of pulau ketam. eighty standard ovitraps were placed indoors and outdoors of randomly selected houses/locations. results demonstrated an endemic baseline aedes population throughout the year without weekly large fluctuations. kampung pulau ketam has high aedes aegypti and aedes albopictus population, but only ae ...201020962714
feeding behavior of mimomyia (etorleptiomyia) luzonensis (ludlow, 1905) (diptera, culicidae) in peninsular malaysia.mosquitoes are vectors of various human diseases in the tropics including yellow fever, dengue, malaria and west nile virus. mosquitoes can act as vectors between wildlife and humans, which is particularly important for diseases where wild animals serve as reservoirs of parasites in the absence of human infections. research has mainly focused on the medical impacts of anopheles, aedes, mansonia and culex, however, very little attention has been directed towards other mosquito genera, especially ...201728359829
genetic polymorphism of aedes albopictus population inferred from nd5 gene variabilities in subang jaya, malaysia.this study was performed to establish the genetic variability of aedes albopictus within subang jaya, selangor, malaysia, by using the nicotinamide adenine dinucleotide dehydrogenase 5 subunit (nd5) mitochondrial dna (mtdna) marker. a total of 90 samples were collected from 9 localities within an area of the subang jaya municipality. genetic variability was determined through the amplification and sequencing of a fragment of the nd5 gene. eight distinct mtdna haplotypes were identified. the evol ...201628206858
antibody neutralization and viral virulence in recurring dengue virus type 2 outbreaks.outbreaks involving dengue viruses (denv) of the same genotype occur in a cyclical pattern in malaysia. two cycles of outbreaks involving dengue virus type 2 (denv-2) of the same genotype occurred in the 1990s in the klang valley, malaysia. sera of patients from the first outbreak and sera of mice inoculated with virus from the same outbreak had poorer neutralization activity against virus of the second outbreak. conversely, patient sera from the second outbreak showed higher neutralization tite ...200717931106
prevalence of dengue fever and dengue hemorrhagic fever in hospital tengku ampuan rahimah, klang, selangor, malaysia.dengue fever and dengue hemorrhagic fever have been known to be endemic and reportable diseases in malaysia since 1971. major outbreaks occurred in 1973, 1982 and in 1998. for the past few decades until now. many studies have been performed to investigate the importance of these two diseases in malaysia. a retrospective study was carried out in hospital tengku ampuan rahimah klang to find the prevalence of these diseases. the data was collected from the record department of this hospital startin ...200516438209
role of primary care providers in dengue prevention and control in the community.dengue fever is a major public health threat in malaysia, especially in the highly urbanized states of selangor and the federal territory of kuala lumpur. it is believed that many seek treatment at the primary care clinics and are not admitted. this study aims at establishing the fact that primary care practitioners, as the first point of patient contacts, play a crucial role in advising patients suspected of having dengue to take early preventive measures to break the chain of dengue transmissi ...201021265251
risk mapping of dengue in selangor and kuala lumpur, malaysia.dengue fever is a recurring public health problem afflicting thousands of malaysians annually. in this paper, the risk map for dengue fever in the peninsular malaysian states of selangor and kuala lumpur was modelled based on co-kriging and geographical information systems. using population density and rainfall as the model's only input factors, the area with the highest risk for dengue infection was given as gombak and petaling, two districts located on opposite sides of kuala lumpur city that ...201223242677
factors affecting dengue fever knowledge, attitudes and practices among selected urban, semi-urban and rural communities in malaysia.dengue fever is a major public health problem in malaysia. this study aimed to assess factors affecting knowledge, attitudes, and practices regarding dengue fever among a selected population in malaysia. a descriptive, community-based, cross sectional study was conducted with 300 participants from three different geographical settings in urban, semi-urban, and rural areas within the states of selangor and kuala lumpur. the questionnaire included questions on demographic data, knowledge, attitude ...201323682436
dengue serotype surveillance among patients admitted for dengue in two major hospitals in selangor, malaysia, 2010-2011.dengue serotype surveillance is important as any changes in serotype distribution may result in an outbreak or increase in severe dengue cases. this study aimed to determine circulating dengue serotypes in two hospitals in selangor. serum samples were collected from patients admitted for dengue at these two major public hospitals i.e. hospital sungai buloh (hsb) and hospital tunku ampuan rahimah (htar) between november 2010 and august 2011 and subjected to real-time rt-pcr using sybr® green. all ...201525801270
temephos resistance in field aedes (stegomyia) albopictus (skuse) from selangor, malaysia.larvae of aedes albopictus obtained from dengue endemic areas in selangor, malaysia were evaluated for their susceptibility to operational dosage of temephos (1 mg/l). larval bioassays were carried out in accordance to modified who standard methods. biochemical microassay of enzymes in ae. albopictus was conducted to detect the emergence of insecticide resistance and to define the mechanisms involved in temephos resistance. the 50% mortality lethal time (lt50) for ae. albopictus tested against t ...201323959487
testing the impact of virus importation rates and future climate change on dengue activity in malaysia using a mechanistic entomology and disease model.we aimed to reparameterize and validate an existing dengue model, comprising an entomological component (cimsim) and a disease component (densim) for application in malaysia. with the model we aimed to measure the effect of importation rate on dengue incidence, and to determine the potential impact of moderate climate change (a 1 °c temperature increase) on dengue activity. dengue models (comprising cimsim and densim) were reparameterized for a simulated malaysian village of 10 000 people, and v ...201525591942
spatio-temporal patterns of dengue in malaysia: combining address and sub-district level.spatio-temporal patterns of dengue risk in malaysia were studied both at the address and the sub-district level in the province of selangor and the federal territory of kuala lumpur. we geocoded laboratory-confirmed dengue cases from the years 2008 to 2010 at the address level and further aggregated the cases in proportion to the population at risk at the sub-district level. kulldorff's spatial scan statistic was applied for the investigation that identified changing spatial patterns of dengue c ...201425545931
assessment of land use factors associated with dengue cases in malaysia using boosted regression trees.the transmission of dengue disease is influenced by complex interactions among vector, host and virus. land use such as water bodies or certain agricultural practices have been identified as likely risk factors for dengue because of the provision of suitable habitats for the vector. many studies have focused on the land use factors of dengue vector abundance in small areas but have not yet studied the relationship between land use factors and dengue cases for large regions. this study aims to cl ...201425113593
Displaying items 1 - 28 of 28