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seroepidemiological survey of hepatitis e in hong kong by recombinant-based enzyme immunoassays.the agent that causes the enterally transmitted form of non-a, non-b hepatitis has been cloned and called hepatitis e virus (hev). we have carried out a seroepidemiological survey on the prevalence of hepatitis e in hong kong. in a retrospective study, serum from 394 patients with acute viral hepatitis and 355 healthy subjects was tested for antibodies to hev (anti-hev) with a recombinant-based enzyme immunoassay. 65 (16.5%) patients with hepatitis were positive for igm anti-hev and 23 (5.8%) we ...19921359270
current seroepidemiology of hepatitis a in hong kong.the current seroepidemiology of hepatitis a in hong kong was examined by testing stored sera from 702 healthy subjects, collected between 1987-1989, for antibody to hepatitis a virus (anti-hav). the overall prevalence of anti-hav antibody was 45.6%. there were significant increases in prevalence of anti-hav antibody with every 10-year increase in age up to age 40. the prevalence of anti-hav antibody was 24% for subjects below age 30 and 89.2% for those above age 30 (p less than 0.0001). socioeco ...19911655968
hepatitis a and b infections in transfusion-dependent thalassaemia from endemic areas.the aim of this study was to determine the prevalence of previous hepatitis a virus (hav) and b virus (hbv) infection which is in 64 transfusion-dependent (td) patients with thalassaemia including 26 patients who were transfused before blood donors were screened for hbv. serial blood samples taken from these 64 patients and 10 non-td beta-thalassaemia intermedia patients during a 3 year period, were tested for antibody to hav (anti-hav), hepatitis b surface antigen (hbsag), antibody to hbsag (an ...19911958422
changing hepatitis a epidemiology among hong kong chinese adolescents: what are the implications?to study the sero-epidemiology of hepatitis a virus (hav) among adolescents in hong kong and analyse the changing patterns of the infection rates.199910483081
epidemiology of hepatitis a in asia and experience with the hav vaccine in hong kong.hepatitis a and hepatitis b infections are prevalent throughout asia. patients infected with hepatitis b virus (hbv) have a higher morbidity and mortality if superinfected with hepatitis a virus (hav). in hong kong, adolescents and young adults are particularly prone to severe hepatitis infection. hepatitis a vaccination of patients with or without chronic hbv infection has been shown to be efficacious and associated with a good safety profile.200010866842
epidemiology of hepatitis a and hepatitis e infection and their determinants in adult chinese community in hong kong.current epidemiology of hepatitis a virus (hav) and hepatitis e virus (hev) in hong kong was evaluated in 936 adult chinese subjects recruited through a telephone interview in 2001. some 15% of the subjects had igg antibodies to both hav and hev while 665 (71.0%) and 176 (18.8%) had anti-hav and anti-hev, respectively. age was the most significant independent factor. six hundred thirty-eight (79.8%) and 165 (20.7%) subjects aged > or =30 had anti-hav and anti-hev, respectively, as compared with ...200414981755
epidemiology and clinical features of sporadic hepatitis e as compared with hepatitis a.to compare the epidemiology and clinical features of two enterically transmitted hepatitis, namely hepatitis e and hepatitis a.200616454833
major human hepatitis a virus genotype in hong kong marine waters and detection by real-time pcr.marine waters from seven sites around hong kong with varying levels of sewage pollution were analyzed for hepatitis a virus (hav) by pcr cloning and dna sequencing of the highly variable vp1/2a junction of the hav genome. phylogenetic analysis of 10 pcr clones from each of the hav-positive marine sites indicated that human hav genotype ib is the most widely distributed type in hong kong waters. a sensitive and quantitative taqman-based pcr method targeting the 5'-noncoding region (5'-ncr) of hav ...201122001296
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