| prevalence of human t-lymphotropic virus in civilian applicants for the united states armed forces. | the wide range in human t-lymphotropic virus (htlv) seroprevalences reported worldwide has made estimates of seroprevalence difficult in unique populations. in this study, the seropositivity of young adult civilian applicants for the us armed forces was determined. | 1992 | 1536338 |
| human t lymphotropic virus type ii (htlv-ii) infection in a cohort of new york intravenous drug users: an old infection? | to identify risk factors for human t lymphotropic virus type ii (htlv-ii) infection in intravenous drug users (ivdus), participants in a longitudinal study of human immunodeficiency virus (hiv) infection in a new york methadone maintenance program were studied. of 270 participants tested for htlv-i/ii, 21 (8%) were seropositive. of those, 15 (71%) had htlv-ii-specific sequences by polymerase chain reaction (pcr) and 1 (5%) had both htlv-i- and -ii-specific sequences; 3 persons with indeterminate ... | 1991 | 1988509 |
| htlv-i-associated myelopathy associated with blood transfusion in the united states: epidemiologic and molecular evidence linking donor and recipient. | six months after receiving 58 units of blood components, a 65-year-old white man from new york city, with no other risk factors for human t-lymphotropic virus type i (htlv-i) infection, developed htlv-i-associated myelopathy/tropical spastic paraparesis (ham/tsp). investigation of blood donors identified a 25-year-old white hispanic woman from florida whose platelets had been given to the patient and who was seropositive for the virus on a serum specimen obtained 2 years after the donation. she ... | 1991 | 1992361 |
| seroepidemiology and clinical aspects of human t-cell lymphotropic virus type i/ii infection in a cohort of intravenous drug users in new york city. | to define further the magnitude, epidemiology, and clinical features of human t-cell lymphotropic/leukemia virus type i/ii (htlv-i/ii) infection in 454 intravenous drug users in new york city, we evaluated previously frozen aliquots of sera for htlv-i/ii antibodies using enzyme-linked immunoassay, western blot, and radioimmunoprecipitation techniques. we found htlv-i/ii infection in 18.9% of the subjects. age (p = 0.001), race (p = 0.001), having a same gender sexual relationship (p = 0.01), and ... | 1991 | 2047026 |
| patterns of hiv-1 and htlv-i/ii in intravenous drug abusers from the middle atlantic and central regions of the usa. | seroprevalence of human immunodeficiency virus type 1 (hiv-1) and human t lymphotropic virus types i and ii (htlv-i/ii) was determined among 1160 intravenous (iv) drug abusers from five drug treatment or medical centers (manhattan, brooklyn, new jersey, detroit, and new orleans). hiv-1 infection ranged from 5% in new orleans to 48% in new york city. hispanics and blacks had a significantly higher rate of hiv-1 infection than whites (p less than .01), but within each group rates were similar betw ... | 1990 | 2373871 |
| prevalence of human t-cell leukemia/lymphoma virus (htlv) type ii infection among high-risk individuals: type-specific identification of htlvs by polymerase chain reaction. | the extent of human t-cell leukemia/lymphoma virus type ii (htlv-ii) infection and its rate of spread have been difficult to determine owing to the serological cross-reactivity between htlv-i and htlv-ii. the present study overcame this problem by directly detecting type-specific proviral sequences by means of the polymerase chain reaction (pcr) and liquid hybridization. screening was performed on a cohort of primarily white intravenous drug abusers (ivdas), and individuals of other behaviorally ... | 1989 | 2790192 |
| human t-cell leukemia virus (htlv-i) p24 antibody in new york city blood product recipients. | human t-cell leukemia virus (htlv-i) is known to be associated with certain hematologic malignancies, and a related virus, htlv-iii/lav, might be the cause of aids. some persons with aids have had evidence of htlv-i infection. unrelated to these findings, it has been suggested that htlv-i is transmitted via blood products. we therefore evaluated the serologic status to the htlv-i core antigen p24 of 48 persons with hemophilia (hem a) receiving factor concentrate therapy (a group at risk for aids ... | 1985 | 2994470 |
| prevalence of antibodies to htlv-i, -ii, and -iii in intravenous drug abusers from an aids endemic region. | antibody prevalences for human t-cell lymphotropic virus (htlv) types i, ii, and iii were determined for 56 intravenous drug abusers from queens, ny. while control serum samples lacked antibodies to all htlv subgroups, seropositivity among drug users was 41% for htlv-iii, 18% for htlv-ii, and 9% for htlv-i. infection by htlv-i and -ii occurred independently of htlv-iii infection. blacks had greater htlv-iii antibody prevalence than whites (54% vs 16%) and were more likely than whites to be serop ... | 1986 | 3009910 |
| evaluation of hiv type 1 western blot-indeterminate blood donors for the presence of human or bovine retroviruses. | from 1985 through 1990, 1100 of 500,000 human blood donations in syracuse, new york were repeatedly reactive by elisa for antibodies to the human immunodeficiency virus type 1 (hiv-1). nine hundred of the elisa-reactive samples were confirmed as negative by western blot (wb), 40 were confirmed as positive, and the remaining 160 sera were indeterminate, reacting mainly with hiv-1 gag gene products. twenty donors with the most reactive indeterminate wb were selected for follow-up studies. four of ... | 1995 | 7786586 |
| prevalence of human t cell lymphotropic virus (htlv) types i and ii and human immunodeficiency virus type 1 infections among persons with hansen's disease in new york city. | one-hundred seven consecutive patients attending a new york hansen's disease clinic from november 1990 through june 1991 were tested for retroviruses. this cohort included 58 patients diagnosed with hansen's disease after the onset of the aids epidemic, 54 of whom immigrated to the united states before diagnosis of hansen's disease (median, 7 years). the overall rate (1.9%) of human t cell lymphotropic virus (htlv) type i infection was low. two (3.6%) of 55 caribbean-born patients had polymerase ... | 1994 | 7930695 |
| detection of human t-lymphotropic virus (htlv) tax sequences in new york city blood donors seronegative for htlv types 1 and 2. | a potential public health concern is the reported detection of the human t-lymphotropic virus (htlv) tax gene in the lymphocytes of up to 11% of a low-risk group of new york city blood donors (nybd). this study aimed to independently confirm the prevalence of htlv tax sequences in 293 nybd. all nybd tested negative for antibodies to htlv types 1 and 2 and htlv tax. htlv tax sequences were not detected in the nybd lymphocytes. these data demonstrate the lack of htlv-1 tax in this group of nybd at ... | 2003 | 12853410 |
| seroprevalence of human t-lymphotropic virus in blacks from a selected central brooklyn population. | human t-cell leukemia virus type i (htlv-i) has been causally linked to adult t-cell leukemia/lymphoma and tropical spastic paraparesis/htlv-i-associated myelopathy. few seroprevalence studies have been carried out in the united states. because of the number of reports of adult t-cell leukemia/lymphoma and tropical spastic paraparesis/htlv-i-associated myelopathy in blacks from central brooklyn, new york, we decided to initiate a seroprevalence study in this community. intravenous drug users and ... | 1994 | 7910512 |
| detection and characterization of human t-cell lymphotropic virus type i (htlv-i) associated t-cell neoplasms in an htlv-i nonendemic region by polymerase chain reaction. | human t-cell lymphotropic virus type i (htlv-i) associated adult t-cell leukemia/lymphoma (atll) occurs endemically in southwestern japan, the caribbean, and west africa, but occurs sporadically in most of the rest of the world. however, because atll and non-htlv-i associated t-cell neoplasms share overlapping clinicopathologic features, the prevalence of atll in nonendemic regions is unknown. in this study, 75 t-cell neoplasms randomly procured from the metropolitan new york city area were exam ... | 1991 | 2039822 |
| possible hiv "super-strain" in new york city; new human t-lymphotropic viruses identified in africa. | | 2005 | 15844234 |
| retroviruses 2004: review of the 2004 cold spring harbor retroviruses conference. | for the past several decades, retrovirologists from around the world have gathered in late may at the cold spring harbor laboratories in new york to present their studies in formal talks and posters, and to discuss their ongoing research informally at the bar or on the beach. as organizers of the 2004 cold spring harbor retroviruses conference, we have been asked by the editors of retrovirology to prepare a review of the meeting for publication on-line. our goal in this review is not to provide ... | 2004 | 15357866 |
| a study of adult t-cell leukemia/lymphoma incidence in central brooklyn. | adult t-cell leukemia/lymphoma (atl), a rare outcome of infection with human t-lymphotropic virus (htlv-i), is endemic in central brooklyn, which has a large caribbean migrant population. previous studies have suggested that htlv-i prevalence in central brooklyn may be similar to that recorded in the caribbean islands. we established a pilot 1-year surveillance program to identify cases of atl in 7 of 10 hospitals serving the residents of 18 zip codes of central brooklyn with a combined populati ... | 1999 | 10048963 |
| t-cell receptor j beta 1/j beta 2 locus rearrangements in an htlv-1-positive t-cell lymphoma with complex chromosomal aberrations. | we report a case of human t-cell lymphotropic virus type 1 (htlv-1)-infected adult t-cell lymphoma that has multiple chromosomal abnormalities, including the presence of an additional 7q22-36, which contains the locus of the t-cell receptor (tcr) beta chain gene. specific tcr j beta 1/j beta 2 gene rearrangements were detected in both marrow and peripheral blood dna, with evidence of further evolution of the transformed clonal population within the peripheral lymphocytes. to our knowledge, this ... | 1996 | 8638612 |
| an enhanced surveillance program for adult t-cell leukemia in central brooklyn. | the brooklyn adult t-cell leukemia/lymphoma (atl) study was developed to estimate the incidence of the human t-cell lymphotropic virus type i (htlv-i)-associated atl in the crown heights/bedford stuyvesant community. this central brooklyn black community is an area which has already been shown in earlier reports to be endemic for htlv-i-associated atl. surveillance has been conducted at seven area hospitals that serve this community, with surveillance already completed at five hospitals. potenti ... | 1994 | 8152275 |
| a multi-institutional experience of autologous stem cell transplantation in north american patients with human t-cell lymphotropic virus type-1 adult t-cell leukemia/lymphoma suggests ineffective salvage of relapsed patients. | | 2009 | 19373596 |