| prevalence of human t cell leukemia virus-i (htlv-i) antibody among populations living in the amazon region of brazil (preliminary report). | forty-three (31.4%) out of 137 serum samples obtained from two indian communities living in the amazon region were found to be positive for htlv-i antibody, as tested by enzyme-linked immunosorbent assay (elisa). eighty-two sera were collected from mekranoiti indians, yielding 39% of positivity, whereas 11 (20.0%) of the 55 tiriyo serum samples had antibody to htlv-i. in addition, positive results occurred in 10 (23.2%) out of 43 sera obtained from patients living in the belem area, who were suf ... | 1990 | 2215230 |
| [infection and disease caused by the human t cell lymphotropic viruses type i and ii in brazil]. | htlv-i/ii infection is present in all regions of brazil, but its prevalence varies according to the geographical area, being higher in bahia, pernambuco and pará. it has been estimated that brazil has the highest absolute number of infected individuals in the world. blood donors screening and research conducted with special groups (indigenous population of brazil, iv drug users and pregnant women) are the major sources of information about these viruses in our country. htlv-i causes adult t cell ... | 2002 | 12621671 |
| identification of human t-cell lymphotropic virus infection in a semi-isolated afro-brazilian quilombo located in the marajó island (pará, brazil). | antibodies to human t-cell lymphotropic virus-1 and 2 (htlv-1 and 2) were tested in 259 inhabitants (98 males and 161 females) of four villages of the marajó island (pará, brazil) using enzyme immunoassays (elisa and western blot). types and subtypes of htlv were determined by nested polymerase chain reaction (pcr) targeting the px, env and 5 ltr regions. htlv-1 infection was detected in santana do arari (2.06%) and ponta de pedras (1%). htlv-2 was detected only in santana do arari (1.06%). sequ ... | 2006 | 16699718 |
| molecular epidemiology of human t-lymphotropic virus type ii infection in amerindian and urban populations of the amazon region of brazil. | molecular characterization of human t-cell lymphotropic virus ii (htlv-ii) isolates in north america and europe has shown the existence of two principal subtypes of the virus, htlv-iia and htlv-iib. subsequent studies on htlv-ii isolates from brazil have suggested the existence of a unique variant phylogenetically related to htlv-iia but phenotypically similar to htlv-iib with respect to the transactivatory protein, tax. this variant has been designated htlv-iic. to better clarify the variabilit ... | 2002 | 12495078 |
| htlv-i associated myelopathy in the northern region of brazil (belém-pará): serological and clinical features of three cases. | three patients (males, black, ages 37, 40 and 57) attended a university clinic with a progressive paraparesis of obscure origin. one patient who referred disease duration of more than 16 years, showed diminished deep reflexes, bilateral babinski's sign, diminished sensation of vibration, abnormal bladder function and back pain. the other two patients (with one and six years of disease duration) complained of weakness in one leg, increased deep reflexes and back pain. babinski's sign and bladder ... | 2002 | 12045818 |
| detection of htlv-iia blood donors in an urban area of the amazon region of brazil (belém, pa). | the human lymphotropic viruses type i (htlv-i) and type ii (htlv-ii) are members of a group of mammalian retroviruses with similar biological properties, and blood transfusion is an important route of transmission. htlv-i is endemic in a number of different geographical areas and is associated with several clinical disorders. htlv-ii is endemic in several indian groups of the americas and intravenous drug abusers in north and south america, europe and southeast asia. during the year of 1995, all ... | 1998 | 9608238 |
| selectivity of human t lymphotropic virus type-1 (htlv-1) and htlv-2 infection among different populations in brazil. | a seroprevalence study for human t lymphotropic virus type-1 (htlv-1) and htlv-2 was conducted in sao paulo, brazil among 2,312 individuals that included following groups: 1,148 volunteer blood donors, 37 patients with tropical spastic paraparesis (tsp), 53 with lymphoproliferative disorders, 171 with a history of multiple blood transfusions, 268 human immunodeficiency virus type-1 (hiv-1) seropositive subjects, and 635 amazonian indians. antibodies to htlv-1/2 were screened by enzyme-linked imm ... | 1993 | 8279633 |
| [molecular characterization of htlv-1/2 among blood donors in belém, state of pará: first description of htlv-2b subtype in the amazon region]. | this study aimed to perform molecular characterization on the human t-cell lymphotropic virus (htlv) infecting blood donors attended at the hematology and hemotherapy center-foundation of pará. dna samples from 79 htlv-seropositive individuals were analyzed by means of the polymerase chain reaction on the px, env and 5'ltr genomic regions; restriction fragment length polymorphism analysis; and sequencing of the 5'ltr region with subsequent phylogenetic analysis. from this, the htlv types and sub ... | 2009 | 19684974 |
| molecular characterization of human t-cell lymphotropic virus coinfecting human immunodeficiency virus 1 infected patients in the amazon region of brazil. | the present work evaluated the epidemiology of human immunodeficiency virus 1/human t-cell lymphotropic virus (hiv-1/htlv) coinfection in patients living in belém (state of pará) and macapá (state of amapá), two cities located in the amazon region of brazil. a total of 169 blood samples were collected. the sera were tested by enzyme-linked immunosorbent assay to determine the presence of antibodies anti-htlv-1/2. confirmation of infection and discrimination of htlv types and subtypes was perform ... | 2005 | 16113884 |
| serological and molecular evidence of htlv-i infection among japanese immigrants living in the amazon region of brazil. | human t-lymphotropic virus type i (htlv-i) infection was investigated in 168 japanese immigrants (64 males and 104 females) living in the tome-acu county located in the state of para, brazil. the serological screening was performed using an enzyme-linked immunosorbent assay, and showed the presence of anti-htlv in four women whose ages ranged from 50 to 88. confirmation of infection and discrimination htlv typing was performed using a nested pcr on the extracted dna targeting the px region. in t ... | 2004 | 15329447 |
| human t-cell lymphotropic virus types i and ii infections in a cohort of patients with neurological disorders in belém, pará, brazil. | serum- and/or- cerebrospinal fluid (csf) samples obtained from 190 patients suffering from chronic, progressive neurological disease were screened for the presence of human t-cell lymphotropic viruses type i (htlv-i) and type ii (htlv-ii) antibodies over a six-year period (1996 to 2001) in belém, pará, brazil. patients were of both sexes (male subjects, 52%) with ages ranging from 2 to 79 years (mean, 35.9). overall, 15 (7.9%) subjects - of whom 12 (80%) were female adults - reacted htlv-i/ii-se ... | 2004 | 15057327 |