| detection of htlv-i and not htlv-ii infection in guinea bissau (west africa) | | 1991 | 2016693 |
| Maternal proviral load and vertical transmission of Human T cell Lymphotropic Virus type 1 in Guinea-Bissau. | Background The relative importance of routes of transmission of Human T cell Lymphotropic Virus type 1 (HTLV-1) in Guinea-Bissau is largely unknown; vertical transmission is thought to be important, but there are very few existing data. We aimed to examine factors associated with transmission in mothers and children in Guinea-Bissau, where HTLV-1 is endemic (prevalence of 5% in the adult population). Methods A cross-sectional survey was performed among mothers and their children (aged <15 ye ... | 2011 | 22066980 |
| higher mortality in hiv-2/htlv-1 co-infected patients with pulmonary tuberculosis in guinea-bissau, west africa, compared to hiv-2-positive htlv-1-negative patients. | to investigate the effect of human t-lymphotropic virus type 1 (htlv-1) on cd4 counts and mortality in tuberculosis (tb) patients with or without human immunodeficiency virus (hiv). | 2010 | 20395161 |
| mortality associated with hiv-1, hiv-2, and htlv-i single and dual infections in a middle-aged and older population in guinea-bissau. | in guinea-bissau hiv-1, hiv-2, and htlv-i are prevalent in the general population. the natural history of hiv/htlv-i single and dual infections has not been fully elucidated in this population. previous studies have shown that combinations of these infections are more common in older women than in men. the present study compares mortality associated with hiv-1, hiv-2, and htlv-i single and dual infections in individuals over 35 years of age within an urban community-based cohort in guinea-bissau ... | 2007 | 18042276 |
| quantification of human t-lymphotropic virus type i (htlv-i) provirus load in a rural west african population: no enhancement of human immunodeficiency virus type 2 pathogenesis, but htlv-i provirus load relates to mortality. | human t-lymphotropic virus type i (htlv-i) provirus load was examined in a cohort of a population in guinea-bissau among whom human immunodeficiency virus (hiv) type 2 is endemic. geometric mean of hiv-2 rna load among htlv-i-coinfected subjects was significantly lower than that in subjects infected with hiv-2 alone (212 vs. 724 copies/ml; p=.02). adjusted for age, sex, and hiv status, the risk of death increased with htlv-i provirus load; mortality hazard ratio was 1.59 for each log10 increase ... | 2003 | 14639534 |
| a community-based study of human immunodeficiency virus type 2 provirus load in rural village in west africa. | a community-based study of provirus load in human immunodeficiency virus (hiv) type 2-infected subjects was done in a rural village in guinea-bissau. hiv-2 provirus load varied considerably, with a geometric mean of 124.3 (95% confidence interval, 86.0-179.6) copies/10(5) cd4 cells, which is a level similar to that found in hiv-1 infection. neither malaria parasitemia, active syphilis, or human t cell leukemia virus coinfection significantly influenced provirus load, nor did age. eleven of 104 h ... | 1996 | 8537668 |
| hiv-1, hiv-2, htlv-i/ii and treponema pallidum infections: incidence, prevalence, and hiv-2-associated mortality in an occupational cohort in guinea-bissau. | the prevalence and incidence of human immunodeficiency virus types 1 and 2 (hiv-1, hiv-2), human t-lymphotropic virus types i and ii (htlv-i/ii), and syphilitic infections and the association between these infections were determined in a cohort of police officers in guinea-bissau. between january 1990 and december 1992, 1,384 subjects (1,241 men and 143 women) were included in the study; and of the first 879 tested, 561 were tested at least for a second time. the overall seroprevalence of hiv-1 ... | 1995 | 7600111 |
| htlv-1 in rural guinea-bissau: prevalence, incidence and a continued association with hiv between 1990 and 2007. | htlv-1 is endemic in guinea-bissau, and the highest prevalence in the adult population (5.2%) was observed in a rural area, caió, in 1990. hiv-1 and hiv-2 are both prevalent in this area as well. cross-sectional associations have been reported for htlv-1 with hiv infection, but the trends in prevalence of htlv-1 and hiv associations are largely unknown, especially in sub saharan africa. in the current study, data from three cross-sectional community surveys performed in 1990, 1997 and 2007, were ... | 2010 | 20525366 |
| studies on toll-like receptor stimuli responsiveness in hiv-1 and hiv-2 infections. | hiv-1 and hiv-2 are two related viruses with distinct clinical outcomes, where hiv-1 is more pathogenic and transmissible than hiv-2. the pathogenesis of both infections is influenced by the dysregulation and deterioration of the adaptive immune system. however, their effects on the responsiveness of innate immunity are less well known. here, we report on toll-like receptor (tlr) stimuli responsiveness in hiv-1 or hiv-2 infections. | 2009 | 19375940 |
| decline in human t-cell lymphotropic virus-1 prevalence in urban areas of bissau, guinea-bissau: exploring the association with hiv infections. | in 2006, a cross-sectional survey of 384 randomly selected houses within a community-based follow-up study was conducted to assess the human t-cell lymphotropic virus (htlv) prevalence in bissau. changes in prevalence and incidence rates were assessed based on a similar survey carried out 10 years earlier. the prevalence of htlv-1 declined significantly from 3.5% in 1996 to 2.3% in 2006. the incidence between 1996 and 2006 was only 0.9/1000 person-years and tended to be higher for women than for ... | 2009 | 19242315 |
| description of a "trans-saharan" strain of human t-lymphotropic virus type 1 in west africa. | the aim of this study was to assess the prevalence and the molecular epidemiology of human t-lymphotropic virus type 1 (htlv-1) in a group of pregnant women living in guinea bissau. we studied 427 consecutive pregnant women attending 10 centers for hiv-1 infection monitoring in bissau. htlv-1 infection was found in 2.6% of the patients. phylogenetic analysis of the long terminal repeat region showed that 10 isolates were of the cosmopolitan subtype (htlv-1a) and that only 1 was of the widespread ... | 2008 | 18398969 |
| high prevalence of hiv-1, hiv-2 and other sexually transmitted infections among women attending two sexual health clinics in bissau, guinea-bissau, west africa. | the objective was to examine the prevalence of hiv-1, hiv-2 and 10 other sexually transmitted infections (stis), and to explore the relationship between hiv and those stis in women attending two sexual health clinics in bissau, guinea-bissau. in all, 711 women with urogenital problems were included. clinical examination was performed and hiv-1, hiv-2, human t-cell lymphotropic virus (htlv)-1, htlv-2 and syphilis were diagnosed by serology. trichomonas vaginalis was examined using wet mount micro ... | 2010 | 21097735 |
| htlv-1 infection in a population-based cohort of older persons in guinea-bissau, west africa: risk factors and impact on survival. | in 1989, a population-based cohort of persons aged > or = 50 years was established in an urban area of guinea-bissau, west africa. overall, 346 persons were interviewed in detail about risk behaviors and had capillary blood drawn. among women, 12.4% were htlv-1 seropositive, compared with 4.6% in men. no htlv-2 was found. seropositivity varied considerably according to place of birth and ethnic group. in women, but not in men, htlv-1 seropositivity was strongly associated with early sexual debut ... | 1998 | 9579561 |
| neurological morbidity among human t-lymphotropic-virus-type-1-infected individuals in a rural west african population. | community-based neurological data about human t lymphotropic virus type 1 (htlv-1) morbidity in sub-saharan africa are scarce. | 2009 | 18977823 |