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evidence of serological cross-reactivities with human immunodeficiency virus types 1 and 2 and human t-lymphotropic virus types i and ii in sera of pregnant women in ibadan, nigeria.our previous studies have indicated that the human immunodeficiency virus (hiv) and human t-lymphotropic virus (htlv) groups of retroviruses are endemic among various populations in nigeria. these viruses are antigenically distinct and antibodies to hiv and htlv do not cross-react, so we studied the prevalence of hiv-1, hiv-2, htlv-i and htlv-ii antibodies in sera of pregnant women attending an antenatal clinic in ibadan, nigeria.19957797344
human t-cell lymphotropic virus in a population of pregnant women and commercial sex workers in south western nigeria.over 20 million persons are infected with htlv-i/ii globally. the virus is endemic in africa and it is also transmitted sexually. continued identification of high risk groups is important for the control of the disease.200718052864
isolation and characterization of a new subtype a variant of human immunodeficiency virus type i from nigeria.we have isolated a new variant of hiv-1 from nigeria, africa. the virus was recovered from the peripheral blood mononuclear cells (pbmcs) of an apparently healthy 23-year-old male from ibadan, nigeria. the in vitro studies indicated that the virus was highly cytopathic and replicated well in normal pbmcs, established t-cell lines and the monocytic cell line u937. the highest replicative titre of the virus was obtained in freshly isolated primary macrophage/monocyte cells which also showed the le ...19968673828
human t-cell lymphotropic virus types i and ii infections in patients with leukaemia/lymphoma and in subjects with sexually transmitted diseases in nigeria.serological assays that distinguish antibodies to human t-cell lymphotropic virus types i (htlv-i) and type ii (htlv-ii), and polymerase chain reaction (pcr) tests were used to investigate association of these two human retroviruses with several well-defined clinical conditions in nigeria. we compared the frequency of htlv-i and htlv-ii infections among patients with lymphopholiferative disorders (n=65), individuals with various sexually transmitted diseases (n=40), patients with genitals candid ...19968634025
frequency of adult t-cell leukaemia/lymphoma and htlv-i in ibadan, nigeria.sera from a small sample of adult blood donors, healthy school children and patients with lymphoma, leukaemia, non-haematologic cancer, congenital and inflammatory disorders from ibadan, nigeria were screened for htlv-i antibody by an enzyme-linked immunoabsorbent assay and confirmed by investigational western blot. seventy-nine of 236 positively screened samples could not be tested for confirmation. seropositive reactivity was observed in nine of 123 blood donors, and 3 of 46 healthy school chi ...19938471436
type-specific immune response to human t cell lymphotropic virus (htlv) type i and type ii infections in nigeria.type-specific antibody responses to human t cell lymphotropic virus type i (htlv-i) and type ii (htlv-ii) were studied in blood samples collected from 25 different locations in nigeria between 1985 and 1991 and stored at the university college hospital in ibadan. a total of 4,153 sera were collected from participants in the national immunity survey of viral infections (n = 1,640), patients with tuberculosis (tb) (n = 140), patients with sexually transmitted diseases (stds) (n = 876), patients wi ...19948166356
some epidemiological features of the human t-cell lymphotropic virus type i (htlv-i) and atl in nigerians.with a seroprevalence rate (spr) of 6%-10% among healthy adult blood donors (abd), nigeria and other african locales represent an endemic zone for htlv-i. we studied spr in patients with leukaemia, lymphomas, solid tumours, and chronic disorders, as well as in groups of men and women with varying sexual lifestyles. serum specimens were screened with elisa and then confirmed with western blot (wb). sexual practices were investigated among volunteers of different sexual backgrounds by means of a q ...19948152310
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