| molecular epidemiology of htlv type i in japan: evidence for two distinct ancestral lineages with a particular geographical distribution. | japan is one of the highest endemic areas of the world for human t cell leukemia-lymphoma virus type i (htlv-i). to gain new insight as to the origin of this virus in japan and especially in the southern islands of the archipelago, we investigated the long terminal repeat (ltr) of 67 newly isolated htlv-i proviral dnas from peripheral blood mononuclear cells of htlv-i-infected individuals for their restriction fragment length polymorphism (rflp). the specimens were from japanese living in differ ... | 1994 | 7888210 |
| clinical features of human t lymphotropic virus type 1-associated uveitis in hokkaido, japan. | to clarify the clinical features of human lymphotropic virus type 1 (htlv-1)-associated uveitis (hau) in patients of hokkaido university hospital, hokkaido, northern japan. | 2013 | 23608951 |
| screening for antibodies to human t-cell leukemia virus type i in japanese breast milk. | japanese breast milk samples were tested for antibodies to human t-cell leukemia virus type i (htlv-1) by particle agglutination (pa) and a line immunoassay (lia). in the pa method, the agglutination reaction between the htlv-1 antibody and sensitized particles occurred at a 1 : 128 dilution of some breast milk samples. the average antibody titer was one order of magnitude lower than that in the serum positive control. a total of 243 human breast milk specimens were assayed by pa, of which 21 sa ... | 2012 | 22687415 |
| prevalence of a human retrovirus in native japanese: evidence for a possible ancient origin. | the origin of a human retrovirus (atlv or htlv-i) is, at present, unknown although carriers of the virus have been found in japan, the caribbean basin and africa. by means of a sero-epidemiological study, the ainu people of hokkaido, located in the northernmost island of japan, were shown to have antibody to the virus in high frequency. since the ainu are regarded as descendants of the pre-agriculture native population of northern japan, this finding appears to indicate that the retrovirus was a ... | 1985 | 2997332 |
| prevalence of human t-cell leukemia virus type 1 (htlv-i) in family members of adult t-cell leukemia (atl) patients in non-atl-endemic hokkaido of japan. | family members of patients with adult t-cell leukemia (atl) in non-atl-endemic hokkaido, the northernmost part of japan, were assessed for the prevalence of htlv-i infection. immunofluorescence assay showed that 53 out of 133 (39.8%) healthy family members of 23 atl patients were positive for antibodies to htlv-i. when general inhabitants in hokkaido were examined, 3 out of 18 (16.7%) family members of 5 seropositive healthy persons had htlv-i antibodies. the overall seropositivity in hokkaido w ... | 1995 | 7669948 |
| factors predisposing to htlv-1 infection in residents of the greater tokyo area. | human t-cell leukemia virus type 1 (htlv-1) is the etiological agent for adult t-cell leukemia. the geographic distribution of htlv-1 carriers is quite uneven in japan and the greatest prevalence is in southwestern japan. because many people move from endemic areas to the greater tokyo area, the geographic distribution might have changed. therefore, we investigated the factors predisposing to htlv-1 infection, including birthplace, for 88 htlv-1-infected individuals in greater tokyo who visited ... | 2008 | 19034610 |
| characteristics of endogenous uveitis in hokkaido, japan. | etiological characteristics of endogenous uveitis vary around the world. there are few epidemiological reports on the etiology of uveitis from areas within asia. we set out to examine the statistical data on uveitis in japan. | 1996 | 8897050 |
| characteristics of endogenous uveitis in hokkaido, japan. | etiological characteristics of endogenous uveitis vary among areas and races around the world. there are few epidemiological reports on the etiology of uveitis from areas within asia. we report statistical data on uveitis in japan. | 1997 | 9034835 |
| prevalence of human t-lymphotropic virus type 1 carriers among pregnant women in hokkaido, japan. | as there is a risk of mtct of htlv-1, the hsgp htlv-1 mtct was organized in 2011. to determine how many pregnant women are infected with htlv-1 in hokkaido, which is the northernmost and the second largest island in japan with a population of 5,467,000 and 39,392 newborns in 2011, the hsgp htlv-1 mtct asked all facilities that may care for pregnant women in hokkaido in july 2013 to provide information on the number of pregnant women who underwent screening for anti-htlv-1 antibody using particle ... | 2014 | 24909551 |
| prevalence of human t-cell leukemia virus type 1 (htlv-i) in general inhabitants in non-adult t-cell leukemia (atl)-endemic hokkaido, japan. | in contrast to adult t-cell leukemia (atl)-endemic southwestern japan, the northernmost island hokkaido has a small number of atl patients annually. in this study, we surveyed 32,587 healthy inhabitants throughout hokkaido for antibodies to human t-cell leukemia virus type 1 (htlv-i). only 244 individuals (0.8%) were seropositive as htlv-i carriers; 0.6% (123 of 19,512) in males and 0.9% (121 of 13,075) in females. in some areas, however, the inhabitants had relatively high seropositivity (> 2%) ... | 1994 | 7772728 |
| prevalence of human t-cell leukemia virus type 1 (htlv-i) in adult t-cell leukemia (atl) in non-atl-endemic hokkaido of japan. | sera and peripheral blood lymphocytes of 40 adult t-cell leukemia (atl) patients in non-atl-endemic hokkaido were examined for the prevalence of human t-cell leukemia virus type 1 (htlv-i). all patients had htlv-i-specific antibodies. when the peripheral lymphocytes were assessed after short-term cultivation, htlv-i antigens and virus particles were detected. the seroprevalence in 96 cases of non-t-cell leukemias and lymphomas and in 30,056 healthy individuals in hokkaido were 3.1% and 0.7%, res ... | 1994 | 7772727 |