| clinical diversity in adult t-cell leukemia-lymphoma. | adult t-cell leukemia-lymphoma (atl) is a unique t-cell cancer first described in japan. we estimate that more than 200 patients a year have been detected in kyushu. the surface phenotype of atl cells characterized by monoclonal antibodies is t3+, t4+, t8-, t11+, and tac+. in all cases the serum is positive for anti-human t-cell leukemia (lymphotropic) virus (htlv-i) antibodies and the atl cells contain the proviral dna of htlv-i. variations in the clinical features of atypical cases suggest a d ... | 1985 | 2861896 |
| accelerated declining tendency of human t-cell leukemia virus type i carrier rates among younger blood donors in kumamoto, japan. | the annual age- and sex-specific human t-cell leukemia virus type i carrier rate of blood donors in kumamoto, kyushu, japan from 1986 to 1990 revealed that the carrier rates of all the age groups below 50 years declined linearly in both sexes (p less than 0.005). furthermore, the annual declining rates relative to the carrier rates of 16-19-year-old and 20-29-year-old males were higher than those of all of the older males (p less than 0.02), and all female age groups below 50 years had higher re ... | 1992 | 1568229 |
| risk of bronchioloalveolar carcinoma in patients with human t-cell lymphotropic virus type 1 (htlv-i): case-control study results. | background: human t-cell lymphotropic virus type 1 (htlv-i) causes not only adult t-cell leukemia (atl) but also htlv-i associated t-cell bronchioloalveolitis, which is often chronic and subclinical. we have experienced eight htvl-i carriers with bronchioloalveolar carcinoma, which is known to arise from bronchioloalveolar pneumocytes. this case-control study clarified the risk of bronchioloalveolar carcinoma in htlv-i carriers. materials and methods: during the past four years, 212 lung cancer ... | 2011 | 21587123 |
| stable human t-lymphotropic virus type i carrier rates for 7 years among a teenaged blood donor cohort of 1986 in kumamoto, japan. | the human t-lymphotropic virus type i (htlv-i) carrier rates for blood donors in kumamoto, kyushu, japan for 8 years, 1986-1993, are currently available. the data show that 16-19-year-olds in 1986 and 20-29-year-olds in 1993 represent nearly the same cohort, because the median age in both groups is 24.5 years in 1993. therefore, comparison of the htlv-i positive rate for the two groups gives an estimate of the change in the rate over 7 years within the cohort. in males, 265 of 22,143 donors (1.2 ... | 1995 | 7658703 |
| seroepidemiology of hepatitis c virus infection in japan and hcv infection in haemodialysis patients. | since january 1990, japanese red cross blood centres have introduced hepatitis c virus screening with a first-generation elisa. from april to december 1992, approximately 0.98% among 10,905,489 blood donations screened by a second-generation assay were anti-hcv-positive in all japan. seropositivity of anti-hcv increased with the age and serum transaminase value in both sexes. in blood donors having a history of transfusion, the anti-hcv reactive rate was 7.4%. the results of the study made by th ... | 1994 | 7522023 |
| the seroprevalence of anti-htlv-1 antibodies in patients with various liver diseases. | the prevalence of antibodies to human t-cell leukemia virus type 1 (htlv-1), which is linked to the etiology of adult t-cell leukemia (atl), was examined in 380 patients with various liver diseases in kumamoto prefecture, southwestern japan, which is one of the most endemic area for htlv-1. eighteen patients with acute hepatitis (ah), 201 chronic hepatitis (ch), 93 liver cirrhosis (lc) 40 hepatocellular carcinoma (hcc) and 28 with other liver diseases were examined. among these patients, 110 pat ... | 1988 | 3229734 |