| The discovery of ATL: an odyssey in restrospect. | Forty years have passed since our initial description of peculiar cases of adult-onset leukemia with abnormal cells having multi-convoluted nuclei and T cell properties, frequent in the southern regions of Japan in the early 1970s. Retrospectively, the study of adult T cell leukemia (ATL) and the related virus HTLV-I was a forerunner for all of human retrovirology, in which AIDS and the related retrovirus HIV were identified a few years later in the 1980s. Using the anti-TAC monoclonal antibody ... | 2011 | 22068231 |
| hla-dp antigens and htlv-1 antibody status among japanese with multiple sclerosis: evidence for an increased frequency of hla-dpw4. | previously, an association between multiple sclerosis (ms) and hla-dpw4 has been reported in scandinavians. in the present study, the distribution of hla-dp antigens was studied in 34 japanese ms patients, all of whom fulfilled the criteria for definite ms. hla-dp typings for dpw1 through w6 and the local specificity, cdp-hei, were performed using the primed lymphocyte typing (plt) technique. in addition, the patients were typed for a dr2+, dw2+/dw12- related, plt defined specificity. the distri ... | 1989 | 2641759 |