| screening of anti-htlv antibody in sera of normal individuals and patients with malignancies in taiwan. | in the present study an immunofluorescence using kh-2 cells as target cells, has been developed for the screening of 1200 serum samples from normal individuals and 450 of cases from patients with various malignancies. the positive anti-htlv-i antibody rate in the former group is 0.083% (1/1200) and while in the latter it is found to be 1.8% (8/450) (including 3 adult t-cell leukemia/lymphoma cases of the 92 hematopoietic and 5 of 358 non-hematopoietic malignancies). the differences between the t ... | 1986 | 2870219 |
| surveys of hiv-1, htlv-i, and other sexually transmitted diseases in female sex workers in taipei city, taiwan, from 1993 to 1996. | between 1993 and 1996 in taipei, taiwan, we studied the prevalences of hiv-1, htlv-i, hsv-2, chlamydia trachomatis, and syphilis infection in female commercial sex workers (csw) and the pathogens' associated risk factors. female csw from nine massage parlors, two karaoke bars (kb), and 22 brothels in taipei city participated in this study. two of 557 (0.4%) kb csws from those who participated during the period from 1993 to 1994 had hiv-1 infection, whereas no kb csws in the periods 1994 to 1995 ... | 1998 | 9665510 |
| adult t-cell leukemia/lymphoma comprising non-floral leukemic cells in taiwan, a country non-endemic for human t-cell leukemia virus type i. | | 2009 | 19603347 |
| seroepidemiology of human t-lymphotropic virus type i infection among intravenous drug abusers in taiwan. | in order to assess seroprevalence of human t-lymphotropic virus type i (htlv-i) infection among intravenous drug abusers in taiwan, serum samples were collected from 858 male study subjects. antibodies against htlv-i (anti-htlv-i) in sera were tested by enzyme-linked immunosorbent assay and confirmed by western blotting. the overall prevalence of anti-htlv-i (2.3%) in drug abusers was significantly higher than that in the general population in taiwan with a relative risk of 4.9, but it was only ... | 1994 | 7911826 |
| seroepidemiology of human t-cell leukemia virus type-i in the republic of korea. | we investigated the prevalence of antibodies to human t-cell leukemia virus type i (htlv-i) associated antigens in various patients and healthy individuals in the republic of korea. seventeen out of 6,255 individuals (0.27%) were seropositive. the positive rate in males was 0.21% and that in females was 0.36%, the sex difference being similar to that in endemic areas in japan. htlv-i carriers were found in seoul and neighboring areas, but not in busan city or jeju island, which are adjacent to k ... | 1986 | 2871003 |
| htlv-1-associated myelopathy: first case reported in taiwan. | taiwan is geographically, culturally, and socially close to southern japan, which is an endemic area of human t-lymphotropic virus type 1-associated myelopathy (ham). taiwan, however, is not an endemic area of ham. we report the first case of ham in a native taiwanese, a 61-year-old woman, without known htlv-1 risk factors. | 1991 | 1950470 |
| htlv-i-positive and htlv-i-negative peripheral t-cell lymphomas in taiwan chinese. | the clinico-pathologic features of 107 adult chinese patients with peripheral t-cell lymphoma (excluding primary cutaneous lymphoma) are described and a comparison between htlvi+ and htlv-i- patients is made. there were 27 htlv-i+ and 80 htlv-i- patients. the virus-positive and -negative groups both had a male predominance and an identical median age of 48. most patients in both groups presented with stage-iv disease, b symptoms, lymphadenopathy and hepatosplenomegaly. the htlv-i+ group had a si ... | 1992 | 1730511 |
| transfusion-transmitted human t-cell lymphotropic virus type i infection in taiwan: a true risk and occasional coinfection with hepatitis c virus shown in a prospective study. | to study the incidence of human t-cell lymphotropic virus (htlv) after blood transfusion in taiwan, serum samples from 699 patients in a prospective study were examined for seroreactivity of anti-htlv. by an enzyme immunoassay, 9 of the 699 recipients were repeatedly positive. serial serum samples of these 9 patients were then confirmed with a western blot analysis and with a polymerase chain reaction (pcr) assay for htlv-i genome. four were already positive for anti-htlv before transfusion, 1 c ... | 1994 | 7913844 |
| evaluation of anti-htlv-1 in physical-checkup individuals and blood donors in taiwan. | the gelatin particle agglutination (gpa) test specific for antibody detection of human t-cell lymphotropic virus type 1 (htlv-1) was used to screen 500 blood donors and 5000 physical-checkup individuals at veterans general hospital-taipei. the positive rate of physical-checkup individuals and the blood donors was 0.18% (9/5000) and 0% (0/5000) respectively. among the 9 gpa positive specimens, eight were confirmed to be positive by western blot analysis and a prevalence rate of 0.16% (8/5000). se ... | 1992 | 1342641 |
| serological survey of antibodies to the adult t-cell leukemia virus-associated antigen (htlv-a) in taiwan. | a serological survey of antibodies to the adult t-cell leukemia virus-associated antigen (htlv-a) conducted in taiwan revealed ii seropositive individuals among 2,565 serum donors tested, which included 1,187 hospital or free clinic patients, 1,065 blood donors and 313 aborigines. the overall prevalence rate was 0.43% and was 0.90% (9/995) for adults aged 40 years or over, which was similar to the rates observed in the non-endemic areas in japan. no highly prevalent area was demonstrated. the ii ... | 1985 | 2993172 |
| distribution and prognosis of who lymphoma subtypes in taiwan reveals a low incidence of germinal-center derived tumors. | to assess the distribution of lymphomas in taiwan according to the who (world health organization) classification, 175 recently diagnosed cases of malignant lymphomas were studied and the clinicopathologic data were analyzed. b-cell lymphomas accounted for 57.1% of cases, t-cell lymphomas 38.9%, and hodgkin's lymphoma 4%. extranodal lymphomas predominated (55.4%). the most common subtype of b-cell lymphoma was diffuse large b-cell lymphoma (33.1%). all tumor types believed to be derived from ger ... | 2004 | 15359636 |
| a pathologic study of childhood lymphoma in taiwan with special reference to peripheral t-cell lymphoma and the association with epstein-barr viral infection. | the authors retrospectively reviewed the clinicopathologic and immunologic features of 65 consecutive cases of childhood lymphoma reported between 1980 and 1989. southern blot hybridization was also performed in 23 cases to study their association with epstein-barr virus (ebv) and human t-cell leukemia virus type 1 (htlv-1). the 65 cases included 56 non-hodgkin's lymphoma (nhl) (86%) and 9 hodgkin's disease (hd) (14%). the nhl could be classified into the following groups: group i, small nonclea ... | 1991 | 1655230 |
| feasibility of human t-lymphotropic virus type i screening using pooled sera. | the human t-cell lymphotropic virus type i (htlv-i) seroprevalence rate among volunteer blood donors in taiwan is low. to study the feasibility of htlv-i enzyme immunoassay (eia) screening using pooled sera, we prospectively compared its sensitivity to that of the routine test for each donor. | 2002 | 12517057 |
| seroprevalence and demographic characteristics of htlv-i among blood donors in taiwan: 1996-1999. | screening for the human t-cell lymphotropic virus type i (htlv-i) and-ii in blood donors was implemented in taiwan beginning in february 1996. the purpose of the present study was to investigate the changes in htlv-i seroprevalence in all unpaid blood donors in taiwan during the period from february 1996 to december 1999 and to determine the influence of age and sex on the htlv-i seropositivity of donors. htlv-i and htlv-ii screening was performed using combined htlv-i/ii immunoassay. repeated r ... | 2001 | 11721972 |
| human t-cell lymphotropic virus type i associated adult t-cell leukaemia/lymphoma in taiwan chinese. | twenty-five chinese patients with human t-cell lymphotropic virus type i (htlv-i) associated adult t-cell leukaemia/lymphoma (atll) were identified in taiwan. no patients had been outside taiwan and none were descendants of japanese heritage. their ages ranged from 28 to 71 years. there were 17 men and eight women. main clinical and laboratory features at presentation were lymphadenopathy (16), skin lesions (11), hepatosplenomegaly (11), pulmonary lesions (11), hypercalcaemia (10) and bone marro ... | 1991 | 1958472 |
| experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a taiwan hospital. | to describe the immunological responses and clinical outcome of coronavirus (sars) infected healthcare workers (hcw) who had been administered with convalescent plasma as a treatment. | 2005 | 16183666 |
| community-based molecular epidemiology of htlv type i in taiwan and kinmen: implication of the origin of the cosmopolitan subtype in northeast asia. | to understand the possible origin and dissemination of htlv-i infection in northeast asia, community-based molecular epidemiological studies were conducted on the kinmen islands (off the coast of fukien province, china) and in taiwan. a total of 3831 taiwanese from 3 townships (pu-li, chu-dung, and pu-tze) and 993 aborigines from 4 tribes in taiwan participated in this study. the prevalence rates of htlv-i infection in adult residents from pu-li, chu-dung, and pu-tze were 0.82, 1.72, and 1.63%, ... | 1999 | 10052753 |
| low prevalence of human t-cell lymphotropic virus type i infection among volunteer blood donors in taiwan. | | 1998 | 9838946 |
| seroindeterminate htlv-1 prevalence and characteristics in blood donors in taiwan. | human t-cell leukemia virus type 1 (htlv-1) is commonly accepted as the cause of adult t-cell leukemia and tropical spastic paraparesis/htlv-1-associated myelopathy. screening of blood donors for htlv-1 and htlv-2 was implemented in taiwan in february 1996. from february 1996 to december 1998, we investigated the seroprevalence of htlv-1 in all unpaid blood donors in taiwan. of 2,578,238 donors in all 6 blood centers, 1793 (0.06%) were seropositive for htlv-1, and 605 (0.023%) were indeterminate ... | 2003 | 12774934 |
| virus infection in patients with histiocytic necrotizing lymphadenitis in taiwan. detection of epstein-barr virus, type i human t-cell lymphotropic virus, and parvovirus b19. | the relationship of epstein-barr virus (ebv), type i human t-cell lymphotropic virus (htlv-i), and parvovirus b19 to histiocytic necrotizing lymphadenitis was studied prospectively in 10 taiwanese patients using materials obtained by fine-needle aspiration and lymph node biopsy. the presence of ebv was detected by in situ hybridization for ebv-encoded rna expression. immunocytochemistry was used to detect virus-encoded protein for ebv and parvovirus b19. dna in situ hybridization and polymerase ... | 2000 | 10874877 |
| seroprevalence of cmv antibodies in a blood donor population and premature neonates in the south-central taiwan. | infection of cytomegalovirus (cmv) via contaminated blood may endanger immunocompromised patients that require transfusion therapy. the aim of this study is to determine the prevalence of cmv antibodies in the blood donor population in southern-central taiwan. a total of 1800 consecutive sera, obtained from tainan blood center of chinese blood services foundation (cbsf), were tested for cmv antibodies by two commercial enzyme immunoassays (eias). of the sera tested, 150 (8.3%) were found to be c ... | 1999 | 10603708 |
| a population-based epidemiological study of human t-cell leukemia virus type i infection in kin-hu, kinmen. | kinmen is a group of small islands located between taiwan and fu-kien province of mainland china. the general population in kinmen are descendants of immigrants from mainland china who began arriving around 317 a.d. since it has been reported that 0.48% of adults in taiwan have htlv-i infection, the decision was made to conduct a community-based epidemiological study in kinmen to understand the origin and dissemination of htlv-i in north-east asia. over 68% of residents of kin-hu township in kin ... | 1996 | 8598305 |
| detection of epstein-barr virus and htlv-i in t-cell lymphomas of skin in taiwan. | viral etiology has been associated with the pathogenesis of t-cell lymphomas of skin (tcls). therefore, we studied the presence of epstein-barr virus (ebv) and type i human t-cell lymphotropic virus (htlv-i) in tumor cells of tcls to determine the significance of these viruses with the disease. a retrospective study was conducted on the skin tissues from 28 chinese patients with tcls. we used in situ hybridization, immunohistochemistry, and polymerase chain reaction to determine the presence of ... | 1998 | 9650697 |
| envelope gene sequences of human t-lymphotropic virus type 1 in taiwan. | three major types of htlv-1 had been proposed, the melanesian type, the zairian type, and the cosmopolitan type, which was further divided into subtypes a, b and c, according to the phylogenetic tree constructed from ltr sequences of current htlv-isolates. in this study, the envelope gene sequences of htlv-1 from 9 taiwanese were analyzed. based on the phylogenetic tree constructed by unweighted pair group method and the sequence homology analysis by gcg computer programs, the envelope gene sequ ... | 1996 | 8634016 |
| molecular subtyping of human t-lymphotropic virus type i (htlv-i) by a nested polymerase chain reaction-restriction fragment length polymorphism analysis of the envelope gene: two distinct lineages of htlv-i in taiwan. | the major type of human t-lymphotropic virus type i (htlv-i), generally referred to as the cosmopolitan type, has been grouped into three subtypes (a, b, and c) by phylogenetic analysis of the long terminal repeat sequences of the viral genome. twelve subtype-specific nucleotide variations have been deduced by comparison between the envelope (env) sequences of 16 htlv-i strains with defined subtypes and 9 taiwanese htlv-i strains. to gain further insights into the molecular epidemiology of htlv- ... | 1997 | 8986945 |
| peripheral t-cell lymphoma in childhood: a report of five cases in taiwan. | we encountered five children with peripheral t-cell lymphoma (ptl) at national taiwan university hospital (ntuh) from 1985-1989. the patients were four boys and one girl, aged between 5 and 13 years. the duration of prediagnostic symptoms varied from 1 month to 5 years. all had pyrexia and lymphadenopathy; one had a prolonged history of granulomatosis with repeated infection. four had hepatosplenomegaly. one patient presented with diffuse pulmonary infiltration and impending respiratory failure. ... | 1994 | 8177142 |
| seroepidemiology of human t-cell lymphotropic virus type i infection in taiwan. | the epidemiological characteristics of human t-cell lymphotropic virus type i infection in taiwan have been explored by an island-wide community-based survey, which was carried out among residents in 19 townships and metropolitan precincts randomly selected through stratified sampling. serum specimens of 7278 healthy subjects were screened by enzyme-linked immunosorbent assay and confirmed by western blot method. a total of 103 subjects showed positive or weak reactions by enzyme-linked immunoso ... | 1988 | 2900678 |
| presence of htlv-i proviral dna in patients with adult t-cell leukemia/lymphoma in taiwan. | human t-lymphotropic virus-i (htlv-i) proviral dna was demonstrated in the leukemic cells of two newly identified cases of adult t-cell leukemia/lymphoma (atl) in taiwan by the southern blot hybridization method. therefore, the atl cases diagnosed clinicopathologically in taiwan were, for the first time, documented to be definitely related to htlv-i. | 1988 | 2899453 |
| characterization of the spectrum of postthymic t-cell malignancies in taiwan. a clinicopathologic study of htlv-1-positive and htlv-1-negative cases. | postthymic t-cell malignancy shows marked geographic, clinicopathologic, and prognostic diversity. the frequency and spectrum of t-cell malignancies in taiwan were investigated. fifty-two patients (35 male and 17 female) with a median age of 49 years, were consecutively encountered between october 1983 and april 1987; these accounted for 39% of non-hodgkin's lymphoma cases seen in our institutions. ten patients (19.3%) had adult t-cell leukemia/lymphoma (atl) associated with human t-cell leukemi ... | 1988 | 2896068 |