| [importance of nosocomial transmission on severe acute respiratory syndrome and its prevention]. | | 2004 | 14756992 |
| the virus that changed my world. | | 2003 | 14691538 |
| severe acute respiratory syndrome (sars): over 100 days into the outbreak. | | 2003 | 15571170 |
| [public health and severe acute respiratory syndrome]. | | 2003 | 14576858 |
| lung pathology of severe acute respiratory syndrome (sars): a study of 8 autopsy cases from singapore. | severe acute respiratory syndrome (sars) is an infectious condition caused by the sars-associated coronavirus (sars-cov), a new member in the family coronaviridae. to evaluate the lung pathology in this life-threatening respiratory illness, we studied postmortem lung sections from 8 patients who died from sars during the spring 2003 singapore outbreak. the predominant pattern of lung injury in all 8 cases was diffuse alveolar damage. the histology varied according to the duration of illness. cas ... | 2003 | 14506633 |
| questions about comparative genomics of sars coronavirus isolates. | | 2003 | 12932399 |
| from the centers for disease control and prevention. severe acute respiratory syndrome--singapore, 2003. | | 2003 | 12824198 |
| severe acute respiratory syndrome in a naval diver. | severe acute respiratory syndrome (sars) is a highly infectious, rapidly progressive, emerging disease. early diagnosis and preventive measures are key for treatment and minimization of secondary spread. in the context of the armed forces, aggressive containment measures are essential to prevent an outbreak. in this study, we present the first reported case, to our knowledge, of sars in a naval diver. the special physical requirements for divers and the potential complications associated with de ... | 2006 | 16808126 |
| [severe acute respiratory syndrome (sars)]. | severe acute respiratory syndrome (sars) is a viral disease, observed primarily in southern china in november 2002, with variable flu-like symptoms and pneumonia, in approx. 5% leading to death from respiratory distress syndrome (rds). the disease was spread over more than 30 states all over the globe by sars-virus-infected travelers. who and cdc received first information about a new syndrome by the end of february 2003, after the first cases outside the republic of china had been observed. a c ... | 2003 | 12811416 |
| severe acute respiratory syndrome--singapore, 2003. | the singapore ministry of health (moh), with assistance from the world health organization (who), has been investigating an outbreak of severe acute respiratory syndrome (sars). this is a novel condition caused by the sars-associated coronavirus (sars-cov) and is characterized by both an atypical pneumonia and efficient nosocomial transmission. this report summarizes epidemiologic features of this outbreak in singapore, including the influence of super spreaders and the national prevention and c ... | 2003 | 12807088 |
| comparative full-length genome sequence analysis of 14 sars coronavirus isolates and common mutations associated with putative origins of infection. | the cause of severe acute respiratory syndrome (sars) has been identified as a new coronavirus. whole genome sequence analysis of various isolates might provide an indication of potential strain differences of this new virus. moreover, mutation analysis will help to develop effective vaccines. | 2003 | 12781537 |
| severe acute respiratory syndrome (sars) in singapore: clinical features of index patient and initial contacts. | severe acute respiratory syndrome (sars) is an emerging viral infectious disease. one of the largest outbreaks of sars to date began in singapore in march 2003. we describe the clinical, laboratory, and radiologic features of the index patient and the patient's initial contacts affected with probable sars. | 2003 | 12781012 |
| preventing local transmission of sars: lessons from singapore. | | 2003 | 12765503 |
| from the centers for disease control and prevention. severe acute respiratory syndrome (sars) and coronavirus testing--united states, 2003. | | 2003 | 12734120 |
| [severe acute respiratory syndrome. a new emergent infectious disease]. | | 2003 | 12732127 |
| severe acute respiratory syndrome (sars) and coronavirus testing--united states, 2003. | cdc and the world health organization (who) are continuing to investigate the multicountry outbreak of severe acute respiratory syndrome (sars). infection with a novel coronavirus has been implicated as a possible cause of sars. this report updates information on u.s. residents with sars and summarizes the clinical histories of the five u.s. residents identified as of april 9, 2003, who have both suspected sars and laboratory evidence of infection with a novel coronavirus. | 2003 | 12731699 |
| strategies adopted and lessons learnt during the severe acute respiratory syndrome crisis in singapore. | in singapore, the military was actively involved in the containment of the outbreak of severe acute respiratory syndrome (sars) last year. the outbreak started in february 2003 with three singapore travellers to hong kong. at that time, nothing was known about the aetiological agent of the atypical pneumonia that was termed sars. unfortunately one of the travellers was a super-spreader, defined as a person with high efficiency for virus transmission, and was responsible for the expansion of the ... | 2005 | 15565739 |
| a study on sars awareness and health-seeking behaviour - findings from a sampled population attending national healthcare group polyclinics. | the study aimed to assess the effectiveness of massive sars public education effort on sars awareness and the conduct of those suspected of having sars. | 2004 | 15531959 |
| management of inpatients exposed to an outbreak of severe acute respiratory syndrome (sars). | this is a prospective observational study of a cohort of inpatients exposed to a severe acute respiratory syndrome (sars) outbreak. strict infection control policies were instituted. the 70 patients exposed to the sars outbreak were isolated from the rest of the hospital. they were triaged, quarantined and cohorted in three open plan wards. selective isolation was carried out immediately when symptoms and signs suspicious of sars manifested clinically. the patients' ages ranged from 21 to 90 yea ... | 2004 | 15501336 |
| mutational dynamics of the sars coronavirus in cell culture and human populations isolated in 2003. | the sars coronavirus is the etiologic agent for the epidemic of the severe acute respiratory syndrome. the recent emergence of this new pathogen, the careful tracing of its transmission patterns, and the ability to propagate in culture allows the exploration of the mutational dynamics of the sars-cov in human populations. | 2004 | 15347429 |
| sars: responding to an unknown virus. | the severe acute respiratory syndrome (sars) is an emerging infection caused by a novel coronavirus which first appeared in southern china at the end of 2002. in early 2003, through a single incident, it spread to hong kong, singapore, canada and vietnam. for busy clinicians in large public hospitals, the response to the virus was initially based on ensuring a high level of protection for staff. however, as the epidemic progressed and more information became available about the virus, procedures ... | 2004 | 15252720 |
| childhood severe acute respiratory syndrome, coronavirus infections and asthma. | severe acute respiratory syndrome (sars) is a new infectious disease caused by a novel coronavirus. children appear to be less susceptible to the sars coronavirus, although the other non-sars coronaviruses can cause respiratory infections in adults and in children of all ages. the exact reasons as to why sars preferentially affects adults, and not children, are still unknown. many hypotheses exist and need to be explored. during the outbreak of sars, there did not appear to be an increase in ast ... | 2004 | 15209951 |
| laboratory-acquired severe acute respiratory syndrome. | | 2004 | 15103000 |
| atypical sars and escherichia coli bacteremia. | we describe a patient with severe acute respiratory syndrome (sars) whose clinical symptoms were masked by escherichia coli bacteremia. sars developed in a cluster of healthcare workers who had contact with this patient. sars was diagnosed when a chest infiltrate developed and when the patient's brother was hospitalized with acute respiratory failure. we highlight problems in atypical cases and offer infection control suggestions. | 2004 | 15030711 |
| healthcare worker seroconversion in sars outbreak. | serum samples were obtained from healthcare workers 5 weeks after exposure to an outbreak of severe acute respiratory syndrome (sars). a sensitive dot blot enzyme-linked immunosorbent assay, complemented by a specific neutralization test, shows that only persons in whom probable sars was diagnosed had specific antibodies and suggests that subclinical sars is not an important feature of the disease. | 2004 | 15030691 |
| mild illness associated with severe acute respiratory syndrome coronavirus infection: lessons from a prospective seroepidemiologic study of health-care workers in a teaching hospital in singapore. | severe acute respiratory syndrome (sars) is a newly recognized infectious disease that has recently emerged in east asia and north america. although the clinical features of acute infection have been well described, mildly symptomatic or asymptomatic infections have not been well characterized. | 2004 | 14767817 |
| analysis of deaths during the severe acute respiratory syndrome (sars) epidemic in singapore: challenges in determining a sars diagnosis. | an outbreak of severe acute respiratory syndrome (sars), an infectious disease attributed to a novel coronavirus, occurred in singapore during the first quarter of 2003 and led to 204 patients with diagnosed illnesses and 26 deaths by may 2, 2003. twenty-one percent of these patients required admission to the medical intensive care unit. during this period, the center for forensic medicine, health sciences authority, singapore, performed a total of 14 postmortem examinations for probable and sus ... | 2004 | 14736283 |
| molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. | severe acute respiratory syndrome (sars) is a newly emerged disease caused by a novel coronavirus (sars-cov), which spread globally in early 2003, affecting over 30 countries. we have used molecular epidemiology to define the patterns of spread of the virus in hong kong and beyond. | 2004 | 14726162 |
| appropriate use of personal protective equipment among healthcare workers in public sector hospitals and primary healthcare polyclinics during the sars outbreak in singapore. | singapore was affected by an outbreak of severe acute respiratory syndrome (sars) from 25 february to 31 may 2003, with 238 probable cases and 33 deaths. | 2005 | 15961624 |
| the estimation of sars incubation distribution from serial interval data using a convolution likelihood. | the incubation period of sars is the time between infection of disease and onset of symptoms. knowledge about the distribution of incubation times is crucial in determining the length of quarantine period and is an important parameter in modelling the spread and control of sars. as the exact time of infection is unknown for most patients, the incubation time cannot be determined. what is observable is the serial interval which is the time from the onset of symptoms in an index case to the onset ... | 2005 | 16013037 |
| asymptomatic sars coronavirus infection among healthcare workers, singapore. | we conducted a study among healthcare workers (hcws) exposed to patients with severe acute respiratory syndrome (sars) before infection control measures were instituted. of all exposed hcws, 7.5% had asymptomatic sars-positive cases. asymptomatic sars was associated with lower sars antibody titers and higher use of masks when compared to pneumonic sars. | 2005 | 16022801 |
| modelling sars data using threshold geometric process. | during the outbreak of an epidemic disease, for example, the severe acute respiratory syndrome (sars), the number of daily infected cases often exhibit multiple trends: monotone increasing during the growing stage, stationary during the stabilized stage and then decreasing during the declining stage. lam first proposed modelling a monotone trend by a geometric process (gp) [x(i), i=1,2,...] directly such that [a(i-1)x(i), i=1,2,...] forms a renewal process for some ratio a>0 which measures the d ... | 2006 | 16345017 |
| sars in singapore--predictors of disease severity. | severe acute respiratory syndrome (sars) affected 8096 individuals in 29 countries, with 774 deaths. in singapore, there were 238 cases of sars with 33 deaths. a retrospective analysis was performed to identify predictors of poor outcome in patients with sars locally. | 2006 | 16829999 |
| clinical and laboratory findings of sars in singapore. | singapore was one of 29 countries worldwide affected by severe acute respiratory syndrome (sars) in 2003. | 2006 | 16830000 |
| laboratory containment of sars virus. | following the severe acute respiratory syndrome (sars) outbreak in 2003, a large number of clinical and environmental samples containing/potentially containing sars coronavirus (sarscov) as well as sars-cov stocks were retained in clinical and research laboratories. the importance of laboratory biosafety was demonstrated by the occurrence of laboratory incidents in singapore, taiwan and beijing. it is imperative that safe practice and techniques, safety equipment and appropriate facility design ... | 2006 | 16830004 |
| tracking sars. | | 2003 | 17896716 |
| sars - my personal battle. | it isn't every day that a doctor becomes a patient. it is more peculiar when it occurs with an unknown mysterious epidemic respiratory illness that kills. severe acute respiratory syndrome (sars) gripped the world in 2003, spreading via air-links and throwing the global economy into disarray. as a practicing physician in singapore, one of the first countries affected, i describe my first-hand account of my battle with this illness, how i acquired this illness in singapore, and eventually quarant ... | 2010 | 21094092 |