| [vergina-like strains of tick-borne encephalitis in russia]. | the greek strain vergina representing an individual third serotype of tick-borne encephalitis (tbe) virus has been compared with 13 tbe strains isolated on the territory of russia and central asia (in kirghizia). a kit of deoxyoligonucleotide probes complementary to genome sites of neudorfle strain of the tbe central european subtype (protein c and prm genes) and of strain sofyin of the eastern subtype (protein e, c, m, prm, ns 1, ns 2b, ns 4b genes) was used in molecular hybridization of nuclei ... | 1995 | 8686262 |
| [the siberian and far-eastern subtypes of tick-borne encephalitis virus registered in russia's asian regions: genetic and antigen characteristics of the strains]. | agar gel precipitation test with cross-adsorbed immune sera was used for the antigenic differentiation of strains of tick-borne encephalitis virus (tbev). fifty strains of the far east tbev serotype and 46 strains of the siberian (aina) tbev serotype were isolated from ixodes persulcatus, which is the main vector of the above tbev subtypes in the asian and european parts of russia. the fragment of the envelope protein gene was sequenced for tbev strains. sequences of new-group strains of the sib ... | 2004 | 15293507 |
| [comparative analysis of virulence of the siberian and far-east subtypes of the tick-born encephalitis virus]. | the siberian subtype of the tick-borne encephalitis virus (tev) is different from the far-east subtype by a moderate virulence observed in siberian hamsters and by a low infection development rate (100 strains were compared). no differences were found in neuro-invasiveness. clinical findings and experiments with monkeys denote the ability of the siberian subtype to provoke severe forms of tick-borne encephalitis (tbe). the inflammation-and-degenerative changes were localized in the brain cortex, ... | 2004 | 15597957 |
| [evolution of tick-borne encephalitis and a problem of evolution of its causative agent]. | the evolution of tick-borne encephalitis (tbe) is marked by the expanded nosological area, the transformation of landscapes, the formation of anthropurgic foci, the change of environmental systems, the increase of mortality rate mainly among urban dwellers, as well as pathomorphism. the evolution of natural tbe virus (tbev) populations was studied in eastern and western siberia, middle urals, and the european part of the nosological area. the paper first describes the types of evolutionary trans ... | 2007 | 18041219 |
| [polytypic strains in the genofund of tick-borne encephalitis virus]. | eighteen polytypic tick-borne encephalitis virus (tbev) strains containing the fragments of e and ns1 protein genes of siberian and far eastern, occasionally siberian and european subtypes were isolated in the european and asian parts of the tick-borne encephalitis (tbe) area. they were identified using real-time polymerase chain reaction, hybridization-fluorescence detection with genotype-specific probes, restriction fragment length polymorphism analysis, and e protein sequencing. the polytypic ... | 2016 | 22905425 |