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clustering of brugia malayi infection in a community in south-sulawesi, indonesia.the present study was undertaken in village karondang in south-sulawesi, indonesia, to investigate the influences of genetic, household and environmental factors on brugia malayi infection. infection status was determined by measuring both microfilariae in night blood and anti-filarial igg4, as a marker for detection of active filarial infection. a total of 171 residents participated in the study; familial relationships between subjects were registered to construct pedigrees and distances betwee ...200010726262
clustering of filarial infection in an age-graded study: genetic, household and environmental influences.a statistical method that analyses correlation structures in families to delineate the contribution of genetic, household and environmental factors on clustering of infection, has been applied to data collected in an area endemic for brugian filariasis in south sulawesi, indonesia. infection was assessed both by microfilaraemia and by anti-filarial igg4. the results confirmed earlier findings that genetic factors play an important role in clustering of infection. when clustering of infection was ...200415074880
comparison of an enzyme linked immunosorbent assay (elisa) and a radioallergosorbent test (rast) for detection of ige antibodies to brugia malayi.the enzyme linked immunosorbent assay (elisa) for specific ige antibodies to brugia malayi was compared with the radioallergosorbent test (rast) for use in immunoepidemiological studies of lymphatic filariasis. sera used were from individuals (aged 5-82 years) living in an area endemic for lymphatic filariasis in south sulawesi, indonesia. the percentage of positive ige elisa reactions (52.6%) among the population was lower than the percentage of positive rast (94.5%). although an overall signif ...200315053782
the development of specific igg4 and ige in a paediatric population is influenced by filarial endemicity and gender.we set out to study how anti-filarial igg4 and ige, which have been studied extensively in adult populations, are influenced by gender and by the degree of filarial endemicity during childhood. development of specific igg4 and ige was examined in 502 children aged 3 months to 12 years, who were resident in 3 villages in south-sulawesi with microfilaria prevalences of 6, 23 and 42 %. specific igg4 and ige could be detected as early as 18 months after birth, in low amounts, and increased to levels ...200011128805
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