| melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis. | low past sun exposure, fair skin type, and polymorphisms of the mc1r gene have been associated with multiple sclerosis (ms) risk. we aimed to investigate the interplay between melanocortin 1 receptor gene variants, red hair/fair skin phenotype, and past environmental sun exposure in ms. | 2008 | 18711112 |
| exposure to infant siblings during early life and risk of multiple sclerosis. | the "hygiene hypothesis" has implicated sibship as a marker of infection load during early life and suggests that exposure or reexposure to infections can influence the developing immune system. viral infection has also been implicated in the pathogenesis of multiple sclerosis (ms). | 2005 | 15671431 |
| seroepidemiological study of infectious mononucleosis in older patients. | in southern tasmania, australia, primary epstein-barr virus infection occurs in adults greater than 30 years of age at a higher frequency (approximately 13% of all cases) than is generally reported for other parts of the world, and approximately 7% of the general population of the region have no antibodies to the virus. epstein-barr virus should not be overlooked as a possible cause of disease in older patients in similar populations elsewhere. | 1989 | 2536757 |
| Anti-HHV-6 IgG titer significantly predicts subsequent relapse risk in multiple sclerosis. | Background: Some of the strongest associations with MS onset are for human herpesviruses, particularly Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6). Their role in MS clinical course is less clear, however. Methods: Prospective cohort of 198 persons with clinically definite MS, followed 2002-5, and serum samples obtained from all subjects at study entry to measure anti-HHV-6 and anti-EBV (Epstein-Barr nuclear antigen [EBNA] and viral capsid antigen [VCA]) IgG titers. Ass ... | 2011 | 22084489 |
| migration and multiple sclerosis in immigrants from united kingdom and ireland to australia: a reassessment. iii: risk of multiple sclerosis in uki immigrants and australian-born in hobart, tasmania. | our previous work suggested that migrants from the united kingdom and ireland (uki) to australia who left their home country at a young age had a longer interval between immigration and onset and likely acquired ms in australia. in the present study, we reassessed australian-born cases of ms identified in hobart, tasmania, a relatively high-risk zone, in our 1981 survey and compared these with cases of ms in uki immigrants incident in australia. the incidence of ms in australian-born residents r ... | 2016 | 26914927 |