| combination of imp-4 metallo-beta-lactamase production and porin deficiency causes carbapenem resistance in a klebsiella oxytoca clinical isolate. | this study shows for the first time the mechanism of carbapenem resistance of a klebsiella oxytoca clinical isolate zc101 recovered from a zhejiang university hospital in hangzhou, china. mic values of imipenem, meropenem, and ertapenem for k. oxytoca zc101 were 16, 16, and 128 microg/ml, respectively. conjugation experiments demonstrated the transferability of a resistance determinant from k. oxytoca zc101 to escherichia coli ec600. results from isoelectric focusing, polymerase chain reactions, ... | 2009 | 19748427 |