association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in african americans and caucasians.identification of biomarkers is needed for development of screening programs to prevent gastric cancer. because racial differences exist in cancer rates, we aimed to evaluate the association between polymorphisms in inflammation-related genes and gastric preneoplastic lesions in african americans and caucasians from louisiana, usa. gastric biopsies from 569 adults (361 african americans and 208 caucasians) undergoing diagnostic endoscopy were used for histological diagnosis and genomic dna extra ...201120473875
screening for helicobacter pylori and nonsteroidal anti-inflammatory drug use in medicare patients hospitalized with peptic ulcer disease.peptic ulcer disease has well-defined causes, with most cases related to helicobacter pylori infection and nonsteroidal anti-inflammatory drug use.19999927097
phenotypic differences between esophageal and gastric intestinal metaplasia.intestinal metaplasia is a cancer precursor in the esophagus and the stomach. marked differences exist between the carcinogenic processes in the two locations in terms of natural history and clinical significance. we investigated biopsies from 52 patients with barrett's esophagus and from 50 patients with gastric intestinal metaplasia in an attempt to throw light on their pathogenic processes. morphologic characteristics, presence of helicobacter pylori (h. pylori), and markers of differentiatio ...200414631367
ascorbic acid, helicobacter pylori and lewis phenotype among blacks and whites in new orleans.gastric juice ascorbic acid concentrations were examined in black and white patients. significantly lower concentrations were found in blacks, in the absence of a significant difference in the plasma concentration of vitamin c between races. blacks had higher prevalence of helicobacter pylori infection, higher gastric ph, more severe acute and chronic inflammation of the gastric mucosa and higher frequency of lewis (a-b-) phenotype. although most of these factors have been related to low ascorbi ...19948080590
helicobacter pylori and gastric carcinoma. serum antibody prevalence in populations with contrasting cancer risks.this investigation examined the correlation between helicobacter pylori (hp) infection, as reflected in immunoglobulin g serum antibodies, and the risk of gastric cancer. serum samples were obtained from populations with contrasting gastric cancer risks. the highest prevalence of hp infection, 93%, was observed in the adult population at highest gastric cancer risk, the residents of pasto, colombia. in the lower risk colombian city of cali, a 63% overall prevalence rate was found. both children ...19902249197
histopathology of gastritis in helicobacter pylori-infected children from populations at high and low gastric cancer risk.infection with helicobacter pylori has been recognized as a cause of gastric carcinoma. although the neoplasia is always detected in adults, the infection starts in childhood. it has been reported that early age at first infection is a determinant of gastric cancer risk. in this study, we examined the histopathology of the gastric mucosa in infected children from a population at high risk for gastric cancer (pasto, colombia) and compared it with that of a lower-risk population (new orleans, la). ...200312673553
early gastric cancer and helicobacter pylori: 34 years of experience at charity hospital in new orleans.good survival rates have been reported for resected early gastric adenocarcinoma (egc) in patients found via screening procedures. however, the prevalence of helicobacter pylori in egc in unscreened populations is unclear. the major purpose of this investigation was to analyze the clinical experience and incidence of h. pylori in unscreened patients presenting with egc at charity hospital over a 34-year period. from 1963 through 1997, the tumor registry at charity hospital compiled data on 2497 ...19989619176
the prevalence of helicobacter pylori: are emergency medicine residents at risk?.helicobacter pylori is strongly associated with peptic ulcer disease and gastric cancer. it is a cause of chronic active gastritis. our hypothesis was that emergency physicians might be at increased risk for infection due to their exposure to gastric contents from procedures performed in the emergency department. our goal was to test a group of emergency physicians for h. pylori infection. in this cross sectional study, we tested a group of volunteers from an emergency medicine residency program ...200011033264
age at acquisition of helicobacter pylori infection: a follow-up study from infancy to adulthood.helicobacter pylori infection is common worldwide, but the time of acquisition is unclear. we investigated this issue in a cohort of children selected retrospectively from a population followed up for 21 years.200211918912
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