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relationship between helicobacter pylori icea, caga, and vaca status and clinical outcome: studies in four different countries.there is continuing interest in identifying helicobacter pylori virulence factors that might predict the risk for symptomatic clinical outcomes. it has been proposed that icea and caga genes are such markers and can identify patients with peptic ulcers. we compared h. pylori isolates from four countries, looking at the caga and vaca genotypes, icea alleles, and presentation of the infection. we used pcr to examine icea, vaca, and caga status of 424 h. pylori isolates obtained from patients with ...199910364597
helicobacter pylori from gastric cancer and duodenal ulcer show same phylogeographic origin in the andean region in colombia.a recent report has shown that the phylogenetic origin of helicobacter pylori based on multi-locus sequence typing (mlst) was significantly associated with the severity of gastritis in colombia. however, the potential relationship between phylogenetic origin and clinical outcomes was not examined in that study. if the phylogenetic origin rather than virulence factors were truly associated with clinical outcomes, identifying a population at high risk for gastric cancer in colombia would be relati ...201425121764
microflora of gastric biopsies from patients with duodenal ulcer and gastric cancer: a comparative study of patients from korea, colombia, and the united states.it remains unclear why the spectrum of h. pylori-related diseases differs among different geographic regions. we examined the non-h. pylori contamination rates of the stomach in patients with duodenal ulcer or gastric adenocarcinoma from three different regions with different spectra of h. pylori-related diseases. gastric biopsies were cultured from patients with duodenal ulcer or histologically proven gastric cancer from seoul, korea; bogota, colombia; and houston, texas. the frequency of non-h ...19989790468
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