chemoprevention of precancerous gastric lesions with antioxidant vitamin supplementation: a randomized trial in a high-risk population.gastric cancer is one of the most common malignancies worldwide. histopathologic studies have identified a sequence of changes in the gastric mucosa that mark the slow progression from normal tissue to carcinoma. epidemiologic evidence suggests that a diet rich in fresh fruit and vegetables could be a protective factor against this disease. this effect may be mediated through antioxidant vitamins.200717227997
antioxidants, helicobacter pylori and stomach cancer in venezuela.a randomized chemoprevention trial on precancerous lesions of the stomach is being conducted in tachira state, venezuela. the aims of the study are to evaluate the efficacy of vitamin supplementation in preventing the progression rate of precancerous lesions. here we report on the pilot phase of the study in which two antioxidant preparations were evaluated on their ability to raise antioxidant levels in plasma and in gastric juice. the study aimed also to determine the antibiotic sensitivity pr ...19968664811
difficulty in eradicating helicobacter pylori in a population at high risk for stomach cancer in venezuela.the bacterium helicobacter pylori (hp) has been implicated in the etiology of precancerous lesions of the stomach and there is evidence suggesting that it may influence the efficacy of chemoprevention of gastric cancer with vitamin c. eradication seldom has been attempted in populations from developing countries, with a high prevalence of hp frequently resistant to metronidazole. a randomized, double-blind, controlled trial to evaluate the efficacy of colloidal bismuth subcitrate (120 mg q.i.d.) ...19948061173
possible association between gastric cancer and bracken fern in venezuela: an epidemiologic explore a possible connection between specific environmental factors that might explain the high rates of stomach cancer in people living in the highlands of western venezuela, an epidemiologic study was conducted in 2 regions of contrasting topography. the regions embrace 3 andean states, mérida, táchira and trujillo, and the vicinal lowland surrounding the maracaibo lake basin of zulia state. statistical sanitary records from 1986 to 1996 comprising 5.5 million people in the study area indi ...200111146454
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