Publications

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distribution of helicobacter pylori in north china.to compare the distribution of virulence-associated genotypes of helicobacter pylori (h pylori) in two areas of north china with different gastric cancer risk and furthermore probe into the pathogenicity of the bacterium.200515962367
[dynamic monitoring of serum pepsinogen among high risk populations of gastric cancer in zhuanghe county].to investigate the dynamic changes of serum pepsinogen (pg) among the high risk populations of gastric cancer.200617200016
[campylobacter pyloridis (cp) infection of gastric mucosa in the high and low risk areas of gastric cancer in liaoning province].gastric biopsies in 690 subjects from the high and low risk areas of gastric cancer were examined for identification of cp in the gastric mucosa by warthin-starry, gimenez and gram's stains. the result showed that the positive rate was 60-62% in the high risk area whereas it was only 12.6% in the low risk area in liaoning province. 81-85% of the positive subjects had active chronic gastritis including chronic superficial and atrophic gastritis. the result indicates a close correlation between th ...19892620634
interaction between gstp1 val allele and h. pylori infection, smoking and alcohol consumption and risk of gastric cancer among the chinese population.glutathione s-transferase p1 (gstp1) is a critical enzyme in the phase ii detoxification pathway. one of the common functional polymorphisms of gstp1 is a→g at nucleotide 313, which results in an amino acid substitution (ile105val) at the substrate binding site and reduced catalytic activity. we evaluated the interaction between gstp1 val allele and helicobacter pylori infection, smoking and alcohol consumption, increasing the risk of gastric cancer among the chinese population. information on p ...201223077566
interaction among caveolin-1 genotypes (rs3807987/rs7804372), h. pylori infection, and risk of gastric cancer in a chinese population.caveolin-1, a candidate tumor suppressor, interacts with a number of transducing molecules and plays a regulatory role in several signaling pathways. recently, a study revealed that cav-1 g14713a (rs3807987)/t29107a (rs7804372) polymorphisms might be associated with the susceptibility to certain cancers. in this study, we evaluated the interaction among caveolin-1 genotypes (rs3807987/rs7804372) and helicobacter pylori infection and increased risk of gastric cancer among the chinese population. ...201424065198
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