| domestic animals as reservoirs for sleeping sickness in three endemic foci in south-eastern uganda. | the persistence of sleeping sickness (human african trypanosomiasis) in some areas of south-eastern uganda has necessitated further investigations, focusing mainly on domestic animals as reservoirs of this disease in three agro-ecological zones. the inter-zone differences in the prevalences of trypanosome infection among cattle (p < 0.001) and pigs (p < 0.001) were significant. overall, 5.0% of the cattle, 13.9% of the pigs and 0.4% of the small ruminants investigated were found to be infected w ... | 2003 | 12803870 |
| trypanosoma brucei: comparison of circulating strains in an endemic and an epidemic area of a sleeping sickness focus. | human sleeping sickness in east africa is characterized by periods of long-term endemicity interspersed with short-term epidemics. the factors generating these huge changes are largely uncharacterized but probably reflect complex interactions among socioeconomic factors, ecological factors, and the movement and diversity of trypanosome strains. to investigate the role of trypanosome strains in the generation of these epidemics, we addressed two important questions. (1) are the trypanosome strain ... | 1998 | 9603485 |
| genetic processes within an epidemic of sleeping sickness in uganda. | reproductive processes within the current ugandan epidemic of sleeping sickness are investigated. genotype frequencies derived from isoenzyme patterns in 44 stocks of trypanosoma brucei s.l. collected in 1988 from tororo, south-east uganda are analysed by single and multiple loci methods. in the single locus method, the hypothesis of random mating is tested by agreement with hardy-weinberg equilibrium. the multiple loci method uses a contingency table approach to detect non-random associations b ... | 1993 | 8415549 |
| control of tsetse and trypanosomiasis transmission in uganda by applications of lambda-cyhalothrin. | the pyrethroid insecticide lambda-cyhalothrin was evaluated in field trials against glossina f.fuscipes and sleeping sickness transmission in iyolwa sub-county, tororo district, uganda. the insecticide was applied selectively to the resting-sites of tsetse, by bush-spraying, using 10% wettable powder (10wp) formulation at an application rate of 11.6 g a.i./ha over an area of 28 km2, or by a 2% electrodyn formulation (2ed) applied at 0.9 g a.i./ha over 30 km2. in a third trial area of 32 km2, 215 ... | 1991 | 1768891 |