Publications

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the efficiency of different diagnostic methods in animal trypanosomiasis; based on surveys carried out in nyanza province, kenya. 19724125897
the role of game animals in the maintenance of endemic and enzootic trypanosomiases in the lambwe valley, south nyanza district, kenya.rhodesian sleeping sickness and bovine trypanosomiasis were endemic in the lambwe valley of western kenya, where the vector of both diseases was a tsetse fly glossina pallidipes. since a large resident population of game animals also inhabited the valley, a programme was designed to assess the relationships between game animals, tsetse, and trypanosome populations and the results were collated with some aspects of local human ecology and the general epidemiological situation in the valley. of 13 ...19724544824
the application of the indirect fluorescent antibody test to samples of sera and dried blood from cattle in the lambwe valley, south nyanza, kenya.the indirect fluorescent antibody test (ift) has been used on a number of occasions to determine the level of trypanosomal antibodies in herds of cattle. in the study reported here, comparisons were made between ifts applied to diluted cattle sera and to dried whole blood on filter paper, and between these studies and the results of a parasitological survey. the results showed that sera diluted 1: 160 gave ift responses similar to those obtained from dried blood spots. however, neither test coul ...19724594592
the investigation of trypanosoma brucei isolates obtained from glossina pallidipes in south nyanza, kenya.during studies to determine the main trypanosoma brucei rhodesiense transmission sites in lambwe valley, western kenya, glossina pallidipes were collected from two areas in the valley and examined for trypanosome infection. t. brucei isolated from infected flies were tested for their response to the lethal effects of human blood (blood incubation infectivity test, biit) and also characterized using isoenzyme electrophoresis. six of the 26 t. brucei tested were biit positive, two of which had enz ...19873669129
a history of sleeping sickness in kenya.gambian sleeping sickness entered what is now kenya from uganda in about 1901 and quickly spread along the kenyan shores and islands of lake victoria, reaching tanzania in 1902. by 1910 the disease had spread 25 miles inland along the kuja and migori rivers and their tributaries. sleeping sickness waxed and waned in these areas despite attempts to control tsetse fly populations by various methods. it was not until 1950, when the use of insecticides (ddt) applied by backpack sprayer proved succes ...19892694984
cerebral trypanosomiasis in naturally-infected cattle in the lambwe valley, south nyanza, kenya.surveys in zebu cattle in the lambwe valley in 1980 indicated that many (up to 70%) were infected with trypanosomes. the predominant parasite was trypanosoma brucei sspl followed by t. congolense. cerebrospinal fluid (csf) analysis showed a high proportion of animals with pleocytosis and elevated total csf protein. trypanosomes were detected in csf and signs of a central nervous system (cns) disease were observed. histopathological lesions in the cns were identical to those found in experimental ...19892619389
blood incubation infectivity test results for trypanosoma brucei sub-group isolates tested in the lambwe valley, south nyanza, kenya. 19734802411
the epidemiology of human sleeping sickness in the lambwe valley, south nyanza, kenya.human infection with trypanosoma rhodesiense in the lambwe valley area of south nyanza, kenya, was first reported in 1959 although t. gambiense sleeping sickness had been the present there since the turn of the century. the two forms of the disease are associated with the presence of the tsetse glossina fuscipes, which is plentiful and widespread throughout the hinterland, including part of the study area, and g. fuscipes in the thickets near the shores of lake victoria and along some of the riv ...19724544822
characterization of trypanozoon stocks from the south nyanza sleeping sickness focus in western kenya.220 trypanosoma (trypanozoon) brucei sp. stocks isolated between 1969 and 1983 from the lambwe valley sleeping sickness focus in south nyanza, western kenya, were characterized by isoenzyme electrophoresis using 12 enzymes. 12 different zymodemes of t. (t.) b. rhodesiense were isolated from patients during the 13-year period and identical stocks were also found in cattle, reedbuck (redunca redunca) and tsetse (glossina pallidipes). cattle may have played an important role in maintaining and incr ...19854095748
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