[the use of the cluster selection method for assessing the status of immunity to controlled infections (measles, diphtheria and tetanus)].the use of the method of cluster selection in mass serological examination makes it possible to obtain statistically significant results with very low expenditures. the coincidence of the results on the number of seronegative children, obtained by the method of cluster selection, with the results of mass serological examination of all children aged 6-7 years in the district (children found to be seronegative to measles constituted 5.5% and 5.0% respectively) is indicative of the statistical sign ...19911759518
[the use of computers and mathematical methods for optimizing epidemic control measures with respect to measles infection].the potentialities of computers for the study of the effectiveness of immunization have been demonstrated and the mathematical model for the prediction of the proportion of children, seronegative to measles, derived on the basis of the data on the average measles morbidity in different groups for a given period. a multifactor analysis of a large scope of data obtained in seroepidemiological survey and a retrospective analysis of measles morbidity on the basis of data collected in two districts o ...19911759519
[the validation of the expediency of a review of the times for revaccinating children against measles].basing on the results of seroepidemiological study, carried out in two districts of moscow by different methods, cluster selection method including, the authors have developed the following recommendations aimed at improving the strategy of revaccination against measles: (1) selective revaccination of only seronegative children or those with poor antimeasles immunity should be carried out, thus making it possible to reduce the number of susceptible children and diminish the risk of postimmunizat ...19911950287
[the use of the results of a statistical analysis for the goal-directed correction of epidemic-control measures with respect to measles].measles morbidity and the state of the immune stratum among children during pre-epidemic, epidemic and post epidemic periods, taken separately, has been analyzed by a specially developed method of statistical analysis. with the immune stratum remaining the same, differences in morbidity rates in different years of the cycle have been revealed. the study has demonstrated that in the presence of a high level of the immune stratum measles morbidity retains its cyclic character, which may be attribu ...19948017126
[the epidemiological efficacy of mass vaccination against measles among the troops].the measles epidemiological situation in russia has deteriorated in the last years. this problem is also actual for military units, where infection has a form of epidemic outbreaks which inflict up to 12% of personnel. the specialists of the moscow military region sanitary-epidemiological detachment have studied the immune status in 20 military units. the results of these studies have shown that 17 units were practically unprotected against measles. on the basis of these results a mass immunizat ...19948165796
[immunizing and immunomodulating activity of wild measles virus at the focus of measles infection].the effect of a wild measles virus circulating in a childhood collective body on the immune status of 80 children has been studied over time. only using enzyme immunoassay was it possible to fully record and assess the degree of booster effect of the virus on children in case of infection transmission. in 25% cases the increment of antibodies was at the expense of specific igm antibodies appearing in the sera of children. by the end of the first month 60% of children developed a relative measles ...19968928511
[genetic characterisation of wild measles strains circulating in european part of russia in 1998-2002].the primary structure of the n-gene cooh terminus of measles virus isolated, 1998-2000, in russia's european part was investigated. the general analysis as well as an analysis of the primary gene structure showed the two group's isolates as belonging to the d4 genotype. a subsequent analysis of the primary structure of the n-gene cooh-terminus of moscow/2002/61 isolated during the 2002 measles outbreak in moscow also showed it as belonging to the d4 genotype. the obtained data are indicative of ...200415293505
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