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nosocomial infection by gentamicin-resistant streptococcus faecalis. an epidemiologic study.enterococci with high-level resistance to gentamicin account for 55% of clinical isolates of enterococci found in patients at the ann arbor veterans administration medical center. we prospectively studied cultures obtained from all 100 patients hospitalized from 1 december 1985 through 23 january 1986 on the surgical and thoracic intensive care units and a general medical floor. ten patients' cultures grew colonies of gentamicin-resistant enterococci--six after admission to the intensive care un ...19873105375
bacteriological comparison between combined and separate sewer discharges in southeastern michigan. 19664956118
bacterial endocarditis in the community hospital.the clinical records of 66 patients with bacterial endocarditis hospitalized in three community hospitals in saginaw, michigan, from 1964 through 1979 were reviewed. data from these nonreferral hospitals demonstrate that infective endocarditis often does not present to the primary care physician with classical physical findings. the etiological organisms were noted to change from being primarily alpha-hemolytic streptococci during the early part of the study to staphylococci and streptococcus fa ...19816796642
molecular analysis of vancomycin-resistant enterococcus faecalis from michigan hospitals during a 10 year period.we evaluated the molecular relatedness of 47 clinical isolates of vancomycin-resistant enterococcus faecalis collected from 15 michigan hospitals from 1991 to 2000. there were 17 pfge strain types for the 47 isolates. ten of 15 hospitals demonstrated interhospital, and three of 15 intrahospital, dissemination of some isolates. forty-two isolates (89.4%) demonstrated vanb resistance. all vana isolates comprised unique pfge groups, suggesting transposon dissemination or the presence of a similar p ...200212003981
'superbug' hurdles key drug barrier. 200212152043
molecular characterization of gentamicin-resistant enterococci in the united states: evidence of spread from animals to humans through food.we evaluated the molecular mechanism for resistance of 360 enterococci for which the gentamicin mics were >/=128 micro g/ml. the aac(6')-ie-aph(2")-ia, aph(2")-ic, and aph(2")-id genes were identified by pcr in isolates from animals, food, and humans. the aph(2")-ib gene was not identified in any of the isolates. two enterococcus faecalis isolates (mics > 1,024 micro g/ml) from animals failed to generate a pcr product for any of the genes tested and likely contain a new unidentified aminoglycosi ...200312624037
vancomycin-resistant staphylococcus aureus isolates associated with inc18-like vana plasmids in michigan.five of the seven cases of vancomycin-resistant staphylococcus aureus (vrsa) infection identified to date have occurred in southeastern michigan. vrsa isolates from the four most recent cases (all from michigan) were characterized. the vana gene was localized to a single plasmid in each vrsa isolate. the pulsed-field gel electrophoresis patterns of chromosomal dna and the restriction profile of the plasmid demonstrated that the four isolates were unique and differed from the first three vrsa iso ...200818056272
environmental occurrence of the enterococcal surface protein (esp) gene is an unreliable indicator of human fecal contamination.the enterococcal surface protein (esp) gene found in enterococcus faecalis and e. faecium has recently been explored as a marker of sewage pollution in recreational waters but its occurrence and distribution in environmental enterococci has not been well-documented. if the esp gene is found in environmental samples, there are potential implications for microbial source tracking applications. in the current study, a total of 452 samples (lake water, 100; stream water, 129; nearshore sand, 96; and ...200819031895
evaluation of public health risks at recreational beaches in lake michigan via detection of enteric viruses and a human-specific bacteriological marker.each year the national resource defense council addresses the quality of us beaches by routine bacterial indicators. in the great lakes region the indicator used is escherichia coli and for 2007 more beaches were closed and impacted than ever before. in this study, water quality was addressed at two lake michigan beaches over the 2004 swimming season by monitoring infectious enteric viruses by cell culture and integrated pcr and for a human sewage marker based on the enterococcal surface protein ...200919118856
outcomes of therapy: vancomycin-resistant enterococcal bacteremia in hematology and bone marrow transplant patients.purpose: the purpose of this study was to evaluate the risk factors associated with the treatment failure and 30-day mortality in hematology and bone marrow transplant patients treated with daptomycin or linezolid for vancomycin-resistant enterococci (vre) bacteremia. the safety and tolerability of therapy was also assessed. methods: this single-center, retrospective study included adult patients admitted to the hematology or bone marrow transplant service with documented vancomycin-resistant en ...201021110047
growing prevalence of vancomycin-resistant enterococcus faecalis in the region with the highest prevalence of vancomycin-resistant staphylococcus aureus. 201121828976
risk factors for and epidemiology of community-onset vancomycin-resistant enterococcus faecalis in southeast michigan.given the known link between vancomycin-resistant enterococcus faecalis (vref) and vancomycin-resistant staphylococcus aureus (vrsa), the recent increase in prevalence of vref in southeast michigan has raised concerns about the presence of a large "community" reservoir of vref. efforts to control its spread face some important challenges.201324011554
epidemiology of vancomycin-resistant enterococcus faecalis: a case-case-control study.although much is known about vancomycin-resistant (vr) enterococcus faecium, little is known about the epidemiology of vr enterococcus faecalis. the predilection of vr e. faecalis to transfer the vancomycin resistance determinant to staphylococcus aureus is much greater than that of vr e. faecium. the epidemiology of vr e. faecalis has important implications regarding the emergence of vancomycin-resistant s. aureus (vrsa); 8 of 13 reported vrsa cases have been from michigan. a retrospective case ...201323070173
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