Publications

TitleAbstractYear
Filter
PMID
Filter
in vitro activity of meropenem against common pathogenic bacteria isolated in taiwan.the in vitro antimicrobial activity of meropenem, in comparison with nine other antimicrobial agents, against 12 different common pathogenic bacteria were evaluated to know the susceptibility of common bacteria to meropenem in taiwan. meropenem was active against most gram-positive, gram-negative, and anaerobic bacteria, including methicillin-sensitive staphylococcus aureus, streptococcus pyogenes, enterococcus faecalis, escherichia coli, klebsiella pneumoniae, enterobacter cloacae, pseudomonas ...19989934544
antimicrobial susceptibilities of clinical isolates of vancomycin-resistant enterococci in taiwan.to understand the antimicrobial resistance patterns of vancomycin-resistant enterococci in taiwan, we tested the in vitro activities of 10 antimicrobial agents against 71 clinical isolates (39 of enterococcus faecalis and 32 of enterococcus faecium) by means of the agar dilution method. resistance was determined on the basis of the minimum inhibitory concentration (mic) of each antimicrobial agent--mic50 and mic90 (minimum concentrations required to inhibit growth of 50% and 90% of isolates, res ...199910063273
in vitro activity of quinupristin/dalfopristin against clinical isolates of common gram-positive bacteria in taiwan.the mics of quinupristin/dalfopristin against common gram-positive bacteria isolated from various clinical specimens at a university hospital in taiwan were determined by the agar dilution method. the tested bacteria included methicillin-resistant staphylococcus aureus (mrsa), methicillin-susceptible s. aureus (mssa), methicillin-resistant staphylococcus epidermidis (mrse), methicillin-susceptible s. epidermidis (msse), streptococcus pyogenes, streptococcus pneumoniae, and enterococcus faecalis. ...199910212757
emergence of vancomycin-resistant enterococci at a university hospital in taiwan: persistence of multiple species and multiple clones.to describe the epidemiology of vancomycin-resistant enterococci (vre) in a university hospital in taipei, taiwan.199910614607
quinupristin-dalfopristin resistance among gram-positive bacteria in taiwan.to understand quinupristin-dalfopristin resistance among clinical isolates of gram-positive bacteria in taiwan, where this agent is not yet available for clinical use, we evaluated 1,287 nonduplicate isolates recovered from january 1996 to december 1999 for in vitro susceptibility to quinupristin-dalfopristin and other newer antimicrobial agents. all methicillin-susceptible staphylococcus aureus (mssa) isolates were susceptible to quinupristin-dalfopristin. high rates of nonsusceptibility to qui ...200011083643
the status of antimicrobial resistance in taiwan among gram-positive pathogens: the taiwan surveillance of antimicrobial resistance (tsar) programme, 2000.in the taiwan surveillance of antimicrobial resistance programme, isolates were collected from 21 hospitals over a 3-month period in 2000 (tsar ii) and rates of resistance in gram-positive pathogens were determined. resistance rates were high including oxacillin resistance in staphylococcus aureus (60%) and coagulase-negative staphylococci (80%), high-level gentamicin resistance (hlgr) in enterococcus faecalis (60%) and penicillin non-susceptibility in streptococcus pneumoniae (69%). oxacillin r ...200415081085
infective endocarditis in patients with liver cirrhosis.infective endocarditis complicating liver cirrhosis is infrequently reported. this study evaluated the clinical features of infective endocarditis in taiwanese patients with liver cirrhosis.200415216401
proficiency of determination of vancomycin susceptibility in enterococci by clinical laboratories in taiwan.eighty clinical microbiology laboratories in taiwan were evaluated for proficiency in the determination of vancomycin susceptibility of enterococci. each laboratory was given 1 vancomycin-sensitive isolate and 3 vancomycin-resistant enterococci (vre) isolates to determine the levels of vancomycin resistance. among a total of 240 tests performed, 153 (63.8%) correctly determined the levels of vancomycin resistance of the survey isolates. seventy eight (98%) of the 80 laboratories accurately ident ...200415340653
nosocomial infections due to methicillin-resistant staphylococcus aureus and vancomycin-resistant enterococci at a university hospital in taiwan from 1991 to 2003: resistance trends, antibiotic usage and in vitro activities of newer antimicrobial agents.a rapid increase of nosocomial methicillin-resistant staphylococcus aureus (mrsa) infection (from 39% in 1991 to 75% in 2003) and vancomycin-resistant enterococci (vre) (from 1.2% in 1996 to 6.1% in 2003) at a university hospital in taiwan was found. the noticeable rise of mrsa and vre was significantly correlated with the increased consumption of glycopeptides, beta-lactam-beta-lactamase inhibitor combinations, extended-spectrum cephalosporins, carbapenems and fluoroquinolones (pearson's correl ...200515975769
predominance of gram-negative bacilli and increasing antimicrobial resistance in nosocomial bloodstream infections at a university hospital in southern taiwan, 1996-2003.while nosocomial infections cause substantial morbidity and mortality, the availability of timely and accurate epidemiological information on nosocomial pathogens is essential to the appropriate selection of empirical therapy. this study analyzed nosocomial bloodstream infections (nbsis) surveillance data to determine trends in the distribution of pathogens and antimicrobial susceptibilities of these pathogens.200616604246
effect of banning vancomycin analogue avoparcin on vancomycin-resistant enterococci in chicken farms in taiwan.avoparcin, a vancomycin analogue, was banned as a feed additive in taiwan in 2000. a nationwide surveillance was conducted to study the prevalence of vancomycin-resistant enterococci (vre) on chicken farms between 2000 and 2003. among the 1021 e. faecalis and 967 e. faecium isolates studied, resistance to tetracycline, erythromycin, high-level aminoglycosides, ciprofloxacin and chloramphenicol either increased or remained high except vancomycin. the proportion of vre decreased, between 2000 and ...200717298380
comparative bactericidal activities of daptomycin, glycopeptides, linezolid and tigecycline against blood isolates of gram-positive bacteria in taiwan.in-vitro mics and minimum bactericidal concentrations (mbcs) of daptomycin, linezolid, tigecycline, vancomycin and teicoplanin against gram-positive bacteria were determined using the broth microdilution method for ten blood isolates each of methicillin-susceptible staphylococcus aureus (mssa), methicillin-resistant s. aureus (mrsa), including two vancomycin-intermediate s. aureus (visa), vancomycin-resistant enterococcus faecium and enterococcus faecalis. one strain of visa was tested in a time ...200818076671
unusual increase of vancomycin-resistant enterococcus faecium but not enterococcus faecalis at a university hospital in taiwan.enterococcal infections at the chang gung memorial hospital, taiwan, have increased significantly in recent years, accompanied by a significant growth of vancomycin resistance from < 1% to 3.8%. however, the significant increase in vancomycin resistance was only found in enterococcus faecium (from 0.5% to 17.4%).200718350732
vancomycin-resistant enterococcal bacteremia: comparison of clinical features and outcome between enterococcus faecium and enterococcus faecalis.vancomycin-resistant enterococci (vre) have emerged as important nosocomial pathogens. this study was conducted to clarify the clinical features and outcome of patients with vancomycin-resistant enterococcal bacteremia.200818473099
vancomycin-resistant enterococci in a tertiary teaching hospital in taiwan.in 2007, an outbreak of vancomycin-resistant enterococci (vre) occurred at taipei medical university, wan fang hospital, taipei, taiwan. the aim of this study was to characterize the mechanism of glycopeptide resistance and to investigate the genetic relatedness among isolates of vre.200919424560
in vitro activity of nemonoxacin (tg-873870), a novel non-fluorinated quinolone, against clinical isolates of staphylococcus aureus, enterococci and streptococcus pneumoniae with various resistance phenotypes in taiwan.the aim of this study was to assess the in vitro activities of nemonoxacin against gram-positive cocci with various resistance phenotypes.200919833635
characterisation of vancomycin-resistant enterococci from hospitalised patients at a tertiary centre over a seven-year period.vancomycin-resistant enterococci (vre) were isolated from 41 patients at a medical centre in southern taiwan from 1999 to 2005. this accounted for 0.55% of 7449 patients with clinical colonisation or infection due to enterococcus species. nine (22%) patients had clinical infections caused by vre. twenty-five (61%) vre isolates were enterococcus faecalis with vana phenotype and vana gene cluster, the remaining 16 (39%) isolates were enterococcus faecium with vanb phenotype and vanb (15 isolates) ...201020170984
the impact of inappropriate antibiotics on bacteremia patients in a community hospital in taiwan: an emphasis on the impact of referral information for cases from a hospital affiliated nursing home.evidence for the impact of inappropriate antimicrobial therapy on bacteremia is mainly from studies in medical centers. we investigated the impact of inappropriate antimicrobial therapy on bacteremia in a community hospital. in particular, patients from the hospital's affiliated nursing home were sent to the hospital with adequate referral information.201324156241
antibiotic susceptibility of commensal bacteria from human milk.recent studies have focused on foodborne or commensal bacteria as vehicles of antibiotic resistance. however, the antibiotic resistance of milk bacteria from healthy donors is still vague in taiwan. for this purpose, human milk samples were obtained from randomly recruited 19 healthy women between 3 and 360 days post-partum. antibiotic susceptibility profile of bacteria from milk samples was determined. about 20 bacterial species were isolated from milk samples including staphylococcus (6 specie ...201626494365
diversity of lactic acid bacteria associated with fresh coffee cherries in taiwan.a total of 102 lactic acid bacteria (lab) were isolated from three different coffee farms in taiwan. these isolates were classified and identified by the restriction fragment length polymorphism analysis and sequencing of 16s ribosomal dna. heterofermentative leuconostoc, and weissella species were the most common lab found in two farms located at an approximate altitude of 800 m. lactococcus lactis subsp. lactis was the most common lab found in the remaining farm was located at an approximate a ...201424292770
can surgical need in patients with naja atra (taiwan or chinese cobra) envenomation be predicted in the emergency department?to investigate the clinical predictors and the aetiologies for surgery in patients with naja atra (taiwan or chinese cobra) envenomation.201627516567
identification of vancomycin-resistant enterococci clones and inter-hospital spread during an outbreak in taiwan.in 2003, nosocomial infections caused by vancomycin-resistant enterococci (vre) occurred rarely in taiwan. between 2003 and 2010, however, the average prevalence of vancomycin resistance among enterococci spp. increased from 2% to 16% in community hospitals and from 3% to 21% in medical centers of taiwan. we used molecular methods to investigate the epidemiology of vre in a tertiary teaching hospital in taiwan.201323556473
in vitro activities of tedizolid and linezolid against gram-positive cocci associated with acute bacterial skin and skin structure infections and pneumonia.tedizolid is a novel, expanded-spectrum oxazolidinone with potent activity against a wide range of gram-positive pathogens. a total of 425 isolates of gram-positive bacteria were obtained consecutively from patients with acute bacterial skin and skin structure infections (absssis) or pneumonia. these isolates included methicillin-susceptible staphylococcus aureus (mssa) (n = 100), methicillin-resistant staphylococcus aureus (mrsa) (n = 100), streptococcus pyogenes (n = 50), streptococcus agalact ...201526248355
high rates of multidrug resistance in enterococcus faecalis and e. faecium isolated from inpatients and outpatients in taiwan.longitudinal national data on resistance in enterococcus faecalis and e. faecium from different sources in taiwan are rare. the present study analyzed data from the taiwan surveillance of antimicrobial resistance program to address this issue. between 2002 and 2010, a total of 1696 e. faecalis and 452 e. faecium isolates were studied. although these 2 species together comprised similar percentages of all enterococci in each study year (94.1-97.2%, p = 0.19), the proportion of e. faecium increase ...201323414747
comparative genomics of community-acquired st59 methicillin-resistant staphylococcus aureus in taiwan: novel mobile resistance structures with is1216v.methicillin-resistant staphylococcus aureus (mrsa) with st59/sccmecv and panton-valentine leukocidin gene is a major community-acquired mrsa (ca-mrsa) lineage in taiwan and has been multidrug-resistant since its initial isolation. in this study, we studied the acquisition mechanism of multidrug resistance in an st59 ca-mrsa strain (pm1) by comparative genomics. pm1's non-β-lactam resistance was encoded by two unique genetic traits. one was a 21,832-bp composite mobile element structure (mes(pm1) ...201223071689
Displaying items 1 - 25 of 25