| human papillomavirus testing for primary screening of cervical cancer precursors. | our objective was to determine whether the addition of human papillomavirus (hpv) testing to screening cytology improves the detection of cervical cancer precursors. women of ages 18-69 years underwent conventional pap cytology and hpv dna testing in a multicenter study in newfoundland, canada. those with positive cytology and/or hpv and a random sample of those with dual negative results were referred for colposcopy. the study enrolled 2098 women. the relative sensitivity of hpv testing was sig ... | 2000 | 11008913 |
| human papillomavirus testing with pap triage for cervical cancer prevention in canada: a cost-effectiveness analysis. | recently published results from a large randomized trial (canadian cervical cancer screening trial study group) suggest that human papillomavirus testing followed by pap smear-based triage for human papillomavirus positive women may be an effective way to screen women for cervical cancer. we determined the potential cost-effectiveness of including human papillomavirus tests for cervical cancer screening for canada and three provinces: alberta, newfoundland and ontario. | 2009 | 19900264 |
| effect of vaginal self-sampling on cervical cancer screening rates: a community-based study in newfoundland. | cervical cancer is highly preventable and treatable if detected early through regular screening. women in the canadian province of newfoundland & labrador have relatively low rates of cervical cancer screening, with rates of around 40 % between 2007 and 2009. persistent infection with oncogenic human papillomavirus (hpv) is a necessary cause for the development of cervical cancer, and hpv testing, including self-sampling, has been suggested as an alternative method of cervical cancer screening t ... | 2015 | 26060041 |
| randomized controlled trial of human papillomavirus testing versus pap cytology in the primary screening for cervical cancer precursors: design, methods and preliminary accrual results of the canadian cervical cancer screening trial (cccast). | since infection with oncogenic human papillomavirus (hpv) has been considered a necessary cause of cervical cancer, tests for oncogenic hpv types have been proposed as adjuncts or replacements to pap cytology. we designed the canadian cervical cancer screening trial (cccast) to compare the relative efficacy of hpv dna testing and pap cytology in primary screening for cervical cancer and its high-grade precursors. cccast randomized women aged 30-69 years in montreal (quebec) and in st. john's (ne ... | 2006 | 16572425 |