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human papillomavirus infection of the cervix in victoria, 1982-1985.cytological evidence of human papillomavirus infection was present in 4.1% of the smear-tests that were received by the victorian cytology (gynaecological) service during 1982-1985. the prevalence rate among women was estimated to be 2.6% in 1984; for one-third of the women this was a change from their previous cytological status. the prevalence of papillomavirus infection was noted to vary with age and referral source; higher proportions were seen in the age group, 20-24 years, and in the cytol ...19873037286
pap smear results of victorian teenagers, 1980-1987.pap smears reported by the victorian cytology (gynaecological) service between 1980 and 1987 for teenagers show a profile of abnormality which is similar to that for women for all ages. more than 90% of the cytology report have consistently been reported as normal or showing minor benign abnormalities only. no evidence of an increasing rate of infection with human papillomavirus is apparent, with the infection rate as determined cytologically being constant at around 4% to 5% during 1981 to 1987 ...19883233083
polymerase chain reaction. a sensitive indicator of the prevalence of human papillomavirus dna in a population with sexually transmitted disease.a total of 311 cervical samples from first attenders at a sexually transmitted disease clinic assayed for human papillomavirus (hpv) dna with viratype (vt) were analyzed with the polymerase chain reaction (pcr) for hpv using hpv l1 consensus primers and typed using l1 type-specific probes for 6/11, 16, 18 and 33. the prevalence of hpv by pcr was almost double that by vt (23.5% as compared to 12.6%, respectively). the increase was due largely to hpv types other than 6/11, 16, 18 and 33 (61.8%), w ...19957631538
vulvar cancer: the cinderella of gynaecological oncology.cancer of the vulva is a rare malignancy that increases progressively with age. the age-standardized incidence averages between 1 and 2 per 100,000 women in western countries. the majority (80-90%) are squamous cell carcinomas, melanoma and adenocarcinoma each accounting for about 5% of cases. internationally, the incidence of vulvar cancer varies more than 30-fold, the highest rates being seen in populations of portuguese south america. in many populations the incidence appears to be stable but ...19957772006
improving consistency in cervical cytology reporting.during the 1970s, the papanicolaou method of classifying cervical cytology specimens and reporting diagnoses was replaced by more descriptive reporting systems. the plethora of reporting terms caused much confusion and a lack of standardization. to improve this situation, "the bethesda system for reporting cervical/vaginal cytologic diagnoses" was approved at a national cancer institute workshop in 1988. in australia, the victorian cervical cytology registry (vccr) was established in 1989. becau ...19938411232
epidemiological characteristics of women with high grade cin who do and do not have human papillomavirus.human papillomavirus infection is an important aetiological agent associated with the development of cervical neoplasia. however, even with the most sensitive methods of detection, human papillomavirus dna has been detected in only 90% of cases of cervical cancer and between 80%-90% of cases of dysplasia. this study aimed to determine if there are epidemiological differences between women who are positive or negative for human papillomavirus, with high grade cervical intraepithelial neoplasia (c ...199910426645
management of women with minor abnormalities of the cervix detected on screening: a qualitative study.to examine the consistency of decisions by pathology staff and general practitioners in managing women in whom minor cervical abnormalities are detected by screening, with current national health and medical research (nhmrc) council guidelines, and to look at reasons for inconsistencies.200111247615
knowledge and acceptance of human papillomavirus vaccination: perspectives of young australians living in melbourne, australia.this paper explores knowledge of and attitudes toward sexually transmissible infections, human papillomavirus (hpv) vaccination and vaccine acceptability among young people in australia. it also explores factors influencing acceptance and attempts to identify gender differences in knowledge and acceptance.200616800395
human papillomavirus genotype prevalence in cervical biopsies from women diagnosed with cervical intraepithelial neoplasia or cervical cancer in melbourne, australia.multicenter international phase iii clinical trials using multivalent human papillomavirus (hpv) vaccines for cervical cancer (cc) prevention are underway. as hpv immunity is type specific, defining hpv genotype prevalence in different regions to ascertain whether predominant types differ geographically is considerably important prior to vaccine implementation. this study aimed to define hpv genotypes present in cc and high-grade dysplasia among women in melbourne, australia. hpv genotype analys ...200616803479
what do gay men know about human papillomavirus? australian gay men's knowledge and experience of anal cancer screening and human papillomavirus.the objective of this study was to determine levels of experience and knowledge concerning anal dysplasia, anal pap smear tests, and human papillomavirus (hpv) among gay and other homosexually active men.200716837830
a study of women's knowledge regarding human papillomavirus infection, cervical cancer and human papillomavirus vaccines.human papillomavirus (hpv) infection is a common sexually transmitted viral infection and is associated with the development of cervical cancer. hpv vaccines are now undergoing phase 3 clinical trials in australia. it is likely that an hpv vaccine will become licensed for use in the near future.200616866792
prevalence of chlamydia trachomatis in a public colposcopy clinic population.chlamydia trachomatis is a major public health issue, with notifications of this sexually transmitted disease continuing to rise in australia. women attending colposcopy clinics are referred for treatment of cervical abnormalities often associated with human papilloma virus (hpv) infection. there is evidence that women who have acquired one sexually transmitted infection, such as hpv, are at higher risk of acquiring another. women attending colposcopy clinics may therefore be at risk of undiagno ...200717524292
abnormal anal cytology in high-risk human papilloma virus infection in hiv-infected australians.to assess the prevalence of abnormal anal cytology and high-risk human papilloma virus (hpv)-type infection in hiv-infected people with a cd4 cell count >300 cells/microl.200817881414
knowledge and awareness of human papillomavirus (hpv): attitudes towards hpv vaccination among a representative sample of women in victoria, australia.a vaccine program is underway to protect women against human papillomavirus (hpv) and thus cervical cancer. previous studies have reported very low levels of hpv knowledge and there has been concern that preventative vaccines might not be readily accepted, given that hpv is transmitted sexually and the optimal time for vaccination is before sexual debut.200717931530
challenges to accepting a human papilloma virus (hpv) vaccine: a qualitative study of australian women.a vaccine that protects women against the two most frequent high-risk genotypes of human papilloma virus (hpv) and the two types that cause 90 percent of genital warts was licensed in june 2006 in the usa and australia. it is important to understand whether a vaccine delivered to young women before the onset of sexual activity would be acceptable. the goal of this project was to investigate the knowledge and awareness of victorian women about cervical cancer and hpv infections, and their beliefs ...200718019286
estimates for cervical abnormalities in vanuatu.to use the pap smear to establish a recent prevalence of cervical abnormalities within a select population in vanuatu, a developing country.200718081580
hypersensitivity reactions to human papillomavirus vaccine in australian schoolgirls: retrospective cohort study.to describe the outcomes of clinical evaluation, skin testing, and vaccine challenge in adolescent schoolgirls with suspected hypersensitivity to the quadrivalent human papillomavirus vaccine introduced in australian schools in 2007.200819050332
what men who have sex with men think about the human papillomavirus vaccine.this study aimed to ascertain the attitudes of men who have sex with men (msm) to the human papillomavirus (hpv) vaccine and to determine the age at which msm would be willing to ask for the hpv vaccine in relation to their age of sexual debut. of 205 msm attending the melbourne sexual health centre between december 2007 and january 2008, 200 (98%; median age 27 years) completed the study questionnaire. only 30% were aware that there was a vaccine available for protection against infection with ...200919153110
interim estimates of human papillomavirus vaccination coverage in the school-based program in australia.in november 2006, the australian government announced the national hpv vaccination program, consisting of a course of prophylactic human papillomavirus (hpv) vaccine for all australian females aged 12-26 years. females aged 12-18 years are vaccinated through school-based programs. the school-based component commenced in april 2007, with the school years targeted varying across jurisdictions. each jurisdiction maintains comprehensive records of hpv doses delivered in the school-based programs alt ...200819374275
hpv genotype prevalence in women with abnormal pap smears in melbourne, australia.carcinoma of the cervix and its precursor, high-grade cervical intraepithelial neoplasia (cin2/3), are associated with persistent oncogenic human papillomavirus (hpv) infection, particularly hpv 16 and 18. hpv genotype distribution varies with severity of cervical disease, patient demographics such as age, as well as geographical location. in this study, hpv genotype prevalence was determined, using the roche linear array genotyping test, among a cohort of 1,676 women being managed with ablative ...200919475612
rapid decline in presentations of genital warts after the implementation of a national quadrivalent human papillomavirus vaccination programme for young women.this study aimed to determine if the australian human papillomavirus (hpv) vaccination programme has had a population impact on presentations of genital warts.200919837728
providing high quality information about human papillomavirus for women after treatment for high-grade cervical dysplasia.the present study aimed to inform the production of a resource for women who have had a high-grade cervical abnormality and are scheduled to undergo testing for human papillomavirus (hpv) at their 12-month follow-up.201020152096
role of the nurse immuniser in implementing and maintaining the national human papillomavirus 'cervical cancer' vaccine rollout through a school-based program in victoria.in an effort to understand the strengths and limitations of current approaches to human papillomavirus vaccine (hpv) delivery in schools, we conducted an audit of nurse immunisers (ni). in this survey of 159 victorian ni, the ni perceived that knowledge, safety and side effects were among the most important issues raised by parents, schoolgirls, and teachers in the school setting. the most common concern identified by nis was the physical layout of the vaccination setting (41%), followed by safe ...201020719232
early effect of the hpv vaccination programme on cervical abnormalities in victoria, australia: an ecological study.australia introduced a human papillomavirus (hpv) vaccination programme with the quadrivalent hpv vaccine for all women aged 12-26 years between 2007 and 2009. we analysed trends in cervical abnormalities in women in victoria, australia, before and after introduction of the vaccination programme.201121684381
The near disappearance of genital warts in young women 4 years after commencing a national human papillomavirus (HPV) vaccination programme.Background Australia provided free quadrivalent human papillomavirus vaccines to 12-18-year-old girls and women aged =26 years from mid-2007 until the end of 2009. After this time, only girls aged 12-13 years had access to free vaccines. Methods Before and after the study, of the proportion of new patients attending Melbourne Sexual Health Centre from mid-2004 to mid-2011, diagnosed with genital warts (GW) by risk group. Results From July 2004 to June 2011, 52?454 new patients were seen at Mel ...201121970896
will vaccinated women attend cervical screening? a population based survey of human papillomavirus vaccination and cervical screening among young women in victoria, australia.objectives: to assess human papillomavirus (hpv) vaccination coverage and attitudes to vaccination and pap screening in young women. design: population-based telephone survey. setting: victoria, australia. participants: 234 women resident in victoria aged 18-28 years in may 2009. main outcome measures: self-reported hpv vaccination uptake, reasons for non-receipt or failure to complete vaccination, knowledge and attitudes about hpv vaccination and pap screening, and cervical screening intentions ...201122204834
NSW annual immunisation coverage report, 2010.This annual report, the second in the series, documents trends in immunisation coverage in NSW for children, adolescents and the elderly, to the end of 2010. Methods: Data from the Australian Childhood Immunisation Register, the NSW School Immunisation Program and the NSW Population Health Survey were used to calculate various measures of population coverage, coverage for Aboriginal children and vaccination timeliness for all children. Results: Over 90% coverage has been reached for children at ...201122060056
attitudes, knowledge and factors associated with human papillomavirus (hpv) vaccine uptake in adolescent girls and young women in victoria, australia.human papillomavirus (hpv) vaccination targets high-risk hpv16/18 that cause 70% of all cancers of the cervix. in australia there is a fully-funded, school-based national hpv vaccination program which has achieved vaccine initiation rate of 82% among age-eligible females. improving hpv vaccination rates is important in the prevention of morbidity and mortality associated with hpv-related disease. this study aimed to identify factors and barriers associated with uptake of the hpv vaccine in the a ...201627564213
how best to interpret mixed human papillomavirus genotypes in high-grade cervical intraepithelial neoplasia lesions.this study aimed to determine human papillomavirus (hpv) genotypes present in biopsy sections from young women of vaccine eligible age living in victoria, australia, with confirmed cervical intraepithelial neoplasia grade 3 (cin3) or adenocarcinoma in situ (ais) using laser capture microdissection (lcm).201424857693
impact of a population-based hpv vaccination program on cervical abnormalities: a data linkage study.australia was one of the first countries to introduce a publicly funded national human papillomavirus (hpv) vaccination program that commenced in april 2007, using the quadrivalent hpv vaccine targeting 12- to 13-year-old girls on an ongoing basis. two-year catch-up programs were offered to 14- to 17- year-old girls in schools and 18- to 26-year-old women in community-based settings. we present data from the school-based program on population-level vaccine effectiveness against cervical abnormal ...201324148310
anal cancers attributed to human papillomavirus are more common in areas in victoria, australia, with higher hiv notifications.anal cancer is more common in men who have sex with men with hiv. we aimed to determine if there was an association between anal squamous cell carcinoma (scc) and hiv notifications in men in victoria, australia, at a population level.201323611469
promoting cervical screening after introduction of the human papillomavirus vaccine: the effect of repeated mass media campaigns.in 2007, australia implemented an ongoing, school-based human papillomavirus (hpv) vaccination programme for school-aged girls, and a catch-up programme for 18-26-year-old women that ran until the end of 2009. the availability of what is widely known as the 'cervical cancer vaccine' means there is the potential for women to believe, incorrectly, that they no longer require regular cervical screening, and this risk needs to be addressed. the current study aimed to assess the effect of three mass ...201323514877
immunisation coverage annual report, 2011.this, the 5th annual immunisation coverage report, documents trends during 2011 for a range of standard measures derived from australian childhood immunisation register data, and national human papillomavirus (hpv) vaccination program register data. the proportion of children 'fully vaccinated' at 12, 24 and 60 months of age was 91.4%, 92.2% and 89.5% respectively. although pneumococcal vaccine had similar coverage at 12 months to other vaccines, coverage was lower for rotavirus at 12 months (83 ...201324882234
human papillomavirus vaccination and cervical cancer screening by socioeconomic status, victoria. 201222509873
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